Source: RGD

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
CUI: C0038358
Disease: Gastric ulcer
Gastric ulcer
0.600 Biomarker RGD These results confirmed the importance of COX-2/PGE2 in the healing mechanism of gastric ulcers and further suggested that the healing-promoting action of PGE2 is mediated by the activation of EP4 receptors and is associated with VEGF expression. 17673547

2007

Entrez Id: 4846
Gene Symbol: NOS3
NOS3
CUI: C0038358
Disease: Gastric ulcer
Gastric ulcer
0.500 Therapeutic RGD Exendin-4, a glucagon-like peptide-1 analogue accelerates healing of chronic gastric ulcer in diabetic rats. 29095895

2017

Entrez Id: 4318
Gene Symbol: MMP9
MMP9
CUI: C0038358
Disease: Gastric ulcer
Gastric ulcer
0.500 Biomarker RGD We investigated the activity and expression of MMP-9 and -2 in ethanol-induced acute gastric ulceration in rats. 17603938

2007

Entrez Id: 847
Gene Symbol: CAT
CAT
CUI: C0038358
Disease: Gastric ulcer
Gastric ulcer
0.500 Biomarker RGD Gastroprotective and antioxidant effects of montelukast on indomethacin-induced gastric ulcer in rats. 17895592

2007

Entrez Id: 7031
Gene Symbol: TFF1
TFF1
CUI: C0038358
Disease: Gastric ulcer
Gastric ulcer
0.230 Biomarker RGD The role of TFF1 in gastric mucosal repair was examined by analysis of the spatio-temporal expression of TFF1 following gastric ulceration in the rat. 11350545

2001

Entrez Id: 4586
Gene Symbol: MUC5AC
MUC5AC
CUI: C0038358
Disease: Gastric ulcer
Gastric ulcer
0.220 Therapeutic RGD Gastric mucosal protection via enhancement of MUC5AC and MUC6 by geranylgeranylacetone. 16240224

2005

Entrez Id: 4586
Gene Symbol: MUC5AC
MUC5AC
CUI: C0038358
Disease: Gastric ulcer
Gastric ulcer
0.220 Biomarker RGD Restraint-induced gastric ulceration was preceded by an up-regulation of iHSP70 and a down-regulation of SP and MUC5AC gene expressions. 11956390

2002

Entrez Id: 183
Gene Symbol: AGT
AGT
CUI: C0038358
Disease: Gastric ulcer
Gastric ulcer
0.210 Therapeutic RGD Angiotensin (1-7) protects against stress-induced gastric lesions in rats. 24231511

2014

Entrez Id: 6750
Gene Symbol: SST
SST
CUI: C0038358
Disease: Gastric ulcer
Gastric ulcer
0.210 Biomarker RGD [Effect of Bnxia Xexin Decoction and its disassembled recipes on somatostatin in rats with stress gastric ulcer]. 17990461

2007

Entrez Id: 4588
Gene Symbol: MUC6
MUC6
CUI: C0038358
Disease: Gastric ulcer
Gastric ulcer
0.210 Therapeutic RGD Gastric mucosal protection via enhancement of MUC5AC and MUC6 by geranylgeranylacetone. 16240224

2005

Entrez Id: 7010
Gene Symbol: TEK
TEK
CUI: C0038358
Disease: Gastric ulcer
Gastric ulcer
0.210 Biomarker RGD The purpose of this study was to evaluate the expression of Tie-2 and Ang-1 and -2 in an acetic acid-induced gastric ulcer healing process in rats. 12768384

2003

Entrez Id: 284
Gene Symbol: ANGPT1
ANGPT1
CUI: C0038358
Disease: Gastric ulcer
Gastric ulcer
0.210 Biomarker RGD The purpose of this study was to evaluate the expression of Tie-2 and Ang-1 and -2 in an acetic acid-induced gastric ulcer healing process in rats. 12768384

2003

Entrez Id: 836
Gene Symbol: CASP3
CASP3
CUI: C0038358
Disease: Gastric ulcer
Gastric ulcer
0.200 Therapeutic RGD Prophylactic efficacy of patchoulene epoxide against ethanol-induced gastric ulcer in rats: Influence on oxidative stress, inflammation and apoptosis. 29339218

2018

Entrez Id: 355
Gene Symbol: FAS
FAS
CUI: C0038358
Disease: Gastric ulcer
Gastric ulcer
0.200 Therapeutic RGD Prophylactic efficacy of patchoulene epoxide against ethanol-induced gastric ulcer in rats: Influence on oxidative stress, inflammation and apoptosis. 29339218

2018

Entrez Id: 356
Gene Symbol: FASLG
FASLG
CUI: C0038358
Disease: Gastric ulcer
Gastric ulcer
0.200 Therapeutic RGD Prophylactic efficacy of patchoulene epoxide against ethanol-induced gastric ulcer in rats: Influence on oxidative stress, inflammation and apoptosis. 29339218

2018

Entrez Id: 5595
Gene Symbol: MAPK3
MAPK3
CUI: C0038358
Disease: Gastric ulcer
Gastric ulcer
0.200 Biomarker RGD [Effect of moxibustion intervention on expression of gastric epidermal growth factor receptor and extracellular signal regulated kinase 1/2 expression in rats with gastric ulcer]. 25518106

2014

Entrez Id: 5594
Gene Symbol: MAPK1
MAPK1
CUI: C0038358
Disease: Gastric ulcer
Gastric ulcer
0.200 Biomarker RGD [Effect of moxibustion intervention on expression of gastric epidermal growth factor receptor and extracellular signal regulated kinase 1/2 expression in rats with gastric ulcer]. 25518106

2014

Entrez Id: 1080
Gene Symbol: CFTR
CFTR
CUI: C0038358
Disease: Gastric ulcer
Gastric ulcer
0.200 Therapeutic RGD [Effects of weile powder on bicarbonate transporters CFTR SLC26A3 and SLC26A6 in gastric ulcers of rats]. 23596793

2013

Entrez Id: 598
Gene Symbol: BCL2L1
BCL2L1
CUI: C0038358
Disease: Gastric ulcer
Gastric ulcer
0.200 Therapeutic RGD Cytoprotective effect of American ginseng in a rat ethanol gastric ulcer model. 24378970

2013

Entrez Id: 596
Gene Symbol: BCL2
BCL2
CUI: C0038358
Disease: Gastric ulcer
Gastric ulcer
0.200 Therapeutic RGD Cytoprotective effect of American ginseng in a rat ethanol gastric ulcer model. 24378970

2013

Entrez Id: 572
Gene Symbol: BAD
BAD
CUI: C0038358
Disease: Gastric ulcer
Gastric ulcer
0.200 Therapeutic RGD Cytoprotective effect of American ginseng in a rat ethanol gastric ulcer model. 24378970

2013

Entrez Id: 4303
Gene Symbol: FOXO4
FOXO4
CUI: C0038358
Disease: Gastric ulcer
Gastric ulcer
0.200 Biomarker RGD Moreover, in the rat gastric ulcers, the mRNA transcript levels of IGF-1, PTEN, Akt-1, Akt-2, FoxO3 and FoxO4 were upregulated in the gastric ulcer margin, with a peak between Days 4 and 8 following 7 h of WRS. 22735908

2012

Entrez Id: 11255
Gene Symbol: HRH3
HRH3
CUI: C0038358
Disease: Gastric ulcer
Gastric ulcer
0.200 Biomarker RGD Role of capsaicin-sensitive nerves and histamine H1, H2, and H3 receptors in the gastroprotective effect of histamine against stress ulcers in rats. 15680274

2005

Entrez Id: 4322
Gene Symbol: MMP13
MMP13
CUI: C0038358
Disease: Gastric ulcer
Gastric ulcer
0.200 Biomarker RGD During gastric ulcer healing, MMP-2, MMP-3, and MMP-13 RNA expression was increased in stromal cells of the gastric mucosa bordering the ulcer, suggesting a prevalent role of non-epithelial cells in pericellular proteolysis. 15375341

2004

Entrez Id: 4314
Gene Symbol: MMP3
MMP3
CUI: C0038358
Disease: Gastric ulcer
Gastric ulcer
0.200 Biomarker RGD During gastric ulcer healing, MMP-2, MMP-3, and MMP-13 RNA expression was increased in stromal cells of the gastric mucosa bordering the ulcer, suggesting a prevalent role of non-epithelial cells in pericellular proteolysis. 15375341

2004