Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 8991
Gene Symbol: SELENBP1
SELENBP1
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.100 Biomarker BEFREE We assessed the role of SBP VVV on the development of CKD in patients with type 2 diabetes (T2D) and hypertension in real life. 30624364

2019

Entrez Id: 8991
Gene Symbol: SELENBP1
SELENBP1
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.100 GeneticVariation BEFREE Using data for 2,180 self-identified White, Black, Chinese, Japanese, and Hispanic participants from the Study of Women's Health Across the Nation, we examined associations among exposure to (higher vs. lower) everyday discrimination at baseline and BP and hypertension (HTN; systolic blood pressure [SBP] ≥ 140 mmHg; diastolic blood pressure [DBP] ≥ 90 mmHg; or self-reported HTN medication use) risk over a 10 year period. 30247506

2019

Entrez Id: 8991
Gene Symbol: SELENBP1
SELENBP1
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.100 GeneticVariation BEFREE This is a pilot randomized-cross-over study in 38 hemodialysis patients (age: 60.4 ± 11.1 years, men: 65.8%) with intradialytic hypertension (intradialytic SBP rise ≥10 mmHg at ≥4 over six consecutive sessions]. 30063644

2019

Entrez Id: 8991
Gene Symbol: SELENBP1
SELENBP1
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.100 GeneticVariation BEFREE After stratifying the subjects according to blood pressure and blood glucose, the positive relationship between RHR and UACR remained in the subjects with normal blood pressure and normal glucose tolerance, while in the hypertension (SBP ≥ 140 mmHg and/or DBP ≥ 90 mmHg) group and the diabetic mellitus (FPG ≥ 7.0 mmol/L and/or PPG ≥ 11.1 mmol/L) group, the relationship disappeared. 31534974

2019

Entrez Id: 8991
Gene Symbol: SELENBP1
SELENBP1
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.100 Biomarker BEFREE <b>Abbreviations:</b> AAP: American Academy of Pediatrics; BMI: body mass index; BP: blood pressure; cm: centimeter; DBP: diastolic blood pressure; HT: hypertension; kg: kilograms; m: meter; NHANES: National Health and Nutrition Examination Survey; ROC: receiver operating characteristic curve; SBP: systolic blood pressure; SBPHR: systolic blood pressure-to-height ratio; SD: standard deviation; WC: waist circumference; WHR: waist-to-height ratio. 31038015

2019

Entrez Id: 8991
Gene Symbol: SELENBP1
SELENBP1
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.100 Biomarker BEFREE Multiple linear regression analysis revealed that baseline ABI was positively and independently associated with the yearly change in brachial SBP and hypertension incidence. 30640883

2019

Entrez Id: 8991
Gene Symbol: SELENBP1
SELENBP1
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.100 Biomarker BEFREE Incident hypertension has been defined as the increase of SBP values over 140 mmHg and/or of DBP over 90 mmHg and or the beginning of an antihypertensive treatment. 30817453

2019

Entrez Id: 8991
Gene Symbol: SELENBP1
SELENBP1
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.100 AlteredExpression BEFREE Mapuche and European schoolchildren show higher levels of SBP with a decrease in sleep time of 30 min; however, there is a higher prevalence of hypertension and obesity in ethnic Mapuches than in European schoolchildren. 31361065

2019

Entrez Id: 8991
Gene Symbol: SELENBP1
SELENBP1
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.100 Biomarker BEFREE We determined the SBP responses to acute antihypertensive drug protocols and the 2-year natural history of patients presenting with severe hypertension. 30520848

2019

Entrez Id: 8991
Gene Symbol: SELENBP1
SELENBP1
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.100 Biomarker BEFREE In deoxycorticosterone acetate (DOCA)-salt hypertension mice, chronic injection of FR (0.3 mg/kg, s.c., daily for seven days) reversed hypertension (vehicle SBP: 149 ± 5 vs. FR SBP: 117 ± 7 mmHg), without any effect on heart rate. 30634050

2019

Entrez Id: 8991
Gene Symbol: SELENBP1
SELENBP1
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.100 GeneticVariation BEFREE Newly defined stage 1 hypertension and elevated BP were associated with increased risk of incident CVD, whereas long-term changes of SBP and DBP had effects of varying degree on CVD incidence. 31116159

2019

Entrez Id: 8991
Gene Symbol: SELENBP1
SELENBP1
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.100 Biomarker BEFREE Chronic VNS therapy slowed the progression of HTN through an attenuation of SBP and by preserving HRV. 30766489

2019

Entrez Id: 8991
Gene Symbol: SELENBP1
SELENBP1
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.100 GeneticVariation BEFREE Inclusion criteria were age between 18 and 75 years, diagnosis of type 2 diabetes, poorly controlled hypertension over the last 12 months (mean clinic systolic blood pressure [SBP] ≥140 mm Hg and/or diastolic blood pressure [DBP] ≥90 mm Hg), access to a mobile phone, and ability to receive text messages and emails. 30964439

2019

Entrez Id: 8991
Gene Symbol: SELENBP1
SELENBP1
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.100 Biomarker BEFREE Moreover, baPWV was only positively correlated with age, hypertension and SBP and inversely correlated with SEVR and ED in multivariable regression model. 30938496

2019

Entrez Id: 8991
Gene Symbol: SELENBP1
SELENBP1
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.100 Biomarker BEFREE Achievement of target SBP without attention to decrease in DBP can increase cardiovascular morbidity in treated arterial hypertension: the Campania Salute Network. 31205199

2019

Entrez Id: 8991
Gene Symbol: SELENBP1
SELENBP1
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.100 Biomarker BEFREE Moreover, increased blood Se concentrations were associated with body mass index (BMI) [odds ratio (OR): 2.56; 95% CI, 1.11, 5.93], high blood pressure [for both systolic and diastolic blood pressures (SBP and DBP); OR: 3.82; 95% CI, 1.47, 7.31 for SBP and OR: 2.56; 95% CI, 1.18, 5.59 for DBP], and hypertriglyceridemia (OR: 3.3; 95% CI, 1.51, 7.2). 30771749

2019

Entrez Id: 8991
Gene Symbol: SELENBP1
SELENBP1
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.100 Biomarker BEFREE One month after discharge, clinic SBP was measured at hypertension unit. 30950973

2019

Entrez Id: 8991
Gene Symbol: SELENBP1
SELENBP1
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.100 Biomarker BEFREE In the prospective cohort, we observed an increased risk for incident hypertension for the upper METS-IR tercile (METS-IR ≥ 46.42; HR: 1.81, 95% CI: 1.41-2.34), adjusted for known cardiovascular risk factors, and observed that METS-IR had greater increases in the predictive capacity for hypertension along with SBP and the Framingham Hypertension Risk Prediction Model compared with other non-insulin-based IR indexes. 31318156

2019

Entrez Id: 8991
Gene Symbol: SELENBP1
SELENBP1
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.100 Biomarker BEFREE Hypertension was defined as SBP at least 140 mmHg and/or DBP at least 90 mmHg, or current hypertension treatment, and was age-standardized to WHO world population. 30817448

2019

Entrez Id: 8991
Gene Symbol: SELENBP1
SELENBP1
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.100 Biomarker BEFREE We defined hypertension as SBP of 140 mmHg or less and/or DBP of at least 90 mmHg, according to the 2010 Chinese guidelines for the management of hypertension. 30817449

2019

Entrez Id: 8991
Gene Symbol: SELENBP1
SELENBP1
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.100 GeneticVariation BEFREE Patients with hypertension have a wide variation in BV parameters.BV does not correlate with SBP. 31463701

2019

Entrez Id: 8991
Gene Symbol: SELENBP1
SELENBP1
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.100 Biomarker BEFREE Hypertension was defined as SBP ≥ 140 mmHg and/or DBP ≥ 90 mmHg or currently taking antihypertensive medicines. 29553846

2019

Entrez Id: 8991
Gene Symbol: SELENBP1
SELENBP1
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.100 Biomarker BEFREE In men, associations with SBP (0.52 mmHg; 95% CI: -0.82, 1.8), DBP (0.41 mmHg; 95% CI: -0.69, 1.5), and hypertension (2% higher odds; 95% CI: -2%, 6%) were weaker.No associations were observed with BC. 31162282

2019

Entrez Id: 8991
Gene Symbol: SELENBP1
SELENBP1
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.100 Biomarker BEFREE A linear relationship was revealed between intradialytic SBP in IDH patients, indicating that the pre-HD and intra-HD SBP were correlated with post-HD SBP. 30325241

2019

Entrez Id: 8991
Gene Symbol: SELENBP1
SELENBP1
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.100 AlteredExpression BEFREE High blood pressure levels at 10 gestational weeks significantly increased the risk of SGA birth (SBP: RR = 1.32, 95% CI: 1.11-1.56; DBP: RR = 1.10, 95% CI: 1.05-1.14). 30631132

2019