Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3978
Gene Symbol: LIG1
LIG1
CUI: C1306460
Disease: Primary malignant neoplasm of lung
Primary malignant neoplasm of lung 		0.060 GeneticVariation BEFREE Our meta-analysis suggested that the rs156641 polymorphism in the LIG1 gene might be associated with an increased risk of lung cancer. 27352326

2015
Entrez Id: 3978
Gene Symbol: LIG1
LIG1
CUI: C1306460
Disease: Primary malignant neoplasm of lung
Primary malignant neoplasm of lung 		0.060 GeneticVariation BEFREE Individuals carrying the LIG1 rs1050298 T genotype had higher risks of lung cancer, especially those with squamous cell carcinoma. 24929328

2014
Entrez Id: 3978
Gene Symbol: LIG1
LIG1
CUI: C1306460
Disease: Primary malignant neoplasm of lung
Primary malignant neoplasm of lung 		0.060 GeneticVariation BEFREE In addition, rs3730859 in LIG1 was also moderately associated with increased risk for lung cancer among Caucasian smokers. 22139380

2012
Entrez Id: 3978
Gene Symbol: LIG1
LIG1
CUI: C1306460
Disease: Primary malignant neoplasm of lung
Primary malignant neoplasm of lung 		0.060 GeneticVariation BEFREE Among African Americans, His/His genotype of ERCC5 His1104Asp (rs17655) was associated with increased lung cancer risk (OR = 1.78; 95% CI: 1.09-2.91), and LIG1 haplotype GGGAA (rs20581, rs156641, rs3730931, rs20579 and rs439132) was associated with reduced lung cancer risk (OR = 0.61; 95% CI: 0.42-0.88). 18709642

2008
Entrez Id: 3978
Gene Symbol: LIG1
LIG1
CUI: C1306460
Disease: Primary malignant neoplasm of lung
Primary malignant neoplasm of lung 		0.060 GeneticVariation BEFREE No association of DNA ligase-I polymorphism with the risk of lung cancer in north-Indian population. 16907646

2006
Entrez Id: 3978
Gene Symbol: LIG1
LIG1
CUI: C1306460
Disease: Primary malignant neoplasm of lung
Primary malignant neoplasm of lung 		0.060 GeneticVariation BEFREE The results of this large case-control study suggest that this LIG1 polymorphism may not play an important role in susceptibility to lung cancer. 12009232

2002