Source: ALL

Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1052133
rs1052133
OGG1 ; CAMK1
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma 		0.100 GeneticVariation BEFREE Our novel findings therefore suggest that hOGG1 Ser326Cys polymorphism is unlikely to play a modifying role in individual susceptibility to breast cancer among Asian women. 12779082

2003
dbSNP: rs1052133
rs1052133
OGG1 ; CAMK1
CUI: C0006142
Disease: Malignant neoplasm of breast
Malignant neoplasm of breast 		0.100 GeneticVariation BEFREE Our novel findings therefore suggest that hOGG1 Ser326Cys polymorphism is unlikely to play a modifying role in individual susceptibility to breast cancer among Asian women. 12779082

2003
dbSNP: rs1052133
rs1052133
OGG1 ; CAMK1
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate 		0.070 GeneticVariation BEFREE These results suggest that hOGG1 may have a role in the repair of 8-OH-dG adducts in prostate tissue and hOGG1 Ser326Cys polymorphism is associated with prostate cancer risk. 14634453

2003
dbSNP: rs1052133
rs1052133
OGG1 ; CAMK1
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma 		0.070 GeneticVariation BEFREE These results suggest that hOGG1 may have a role in the repair of 8-OH-dG adducts in prostate tissue and hOGG1 Ser326Cys polymorphism is associated with prostate cancer risk. 14634453

2003
dbSNP: rs1052133
rs1052133
OGG1 ; CAMK1
CUI: C1867441
Disease: Pterygium Of Conjunctiva And Cornea
Pterygium Of Conjunctiva And Cornea 		0.010 GeneticVariation BEFREE Our findings suggest that the 1245C --> G transition in exon 7 of the hOGG1 gene, which results in Ser326Cys substitution of the enzyme, might play a role in the susceptibility of humans to pterygium. 14716324

2004
dbSNP: rs1052133
rs1052133
OGG1 ; CAMK1
CUI: C0033999
Disease: Pterygium
Pterygium 		0.010 GeneticVariation BEFREE Our findings suggest that the 1245C --> G transition in exon 7 of the hOGG1 gene, which results in Ser326Cys substitution of the enzyme, might play a role in the susceptibility of humans to pterygium. 14716324

2004
dbSNP: rs1052133
rs1052133
OGG1 ; CAMK1
CUI: C4520843
Disease: Pterygium of eye
Pterygium of eye 		0.010 GeneticVariation BEFREE Our findings suggest that the 1245C --> G transition in exon 7 of the hOGG1 gene, which results in Ser326Cys substitution of the enzyme, might play a role in the susceptibility of humans to pterygium. 14716324

2004
dbSNP: rs1052133
rs1052133
OGG1 ; CAMK1
CUI: C0242379
Disease: Malignant neoplasm of lung
Malignant neoplasm of lung 		0.100 GeneticVariation BEFREE These results suggest that the hOGG1 Ser326Cys polymorphism plays an important role in the risk for lung cancer and is linked to exposure to tobacco smoke. 15077011

2004
dbSNP: rs1052133
rs1052133
OGG1 ; CAMK1
CUI: C1306460
Disease: Primary malignant neoplasm of lung
Primary malignant neoplasm of lung 		0.100 GeneticVariation BEFREE These results suggest that the hOGG1 Ser326Cys polymorphism plays an important role in the risk for lung cancer and is linked to exposure to tobacco smoke. 15077011

2004
dbSNP: rs1052133
rs1052133
OGG1 ; CAMK1
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung 		0.100 GeneticVariation BEFREE These results suggest that the hOGG1 Ser326Cys polymorphism plays an important role in the risk for lung cancer and is linked to exposure to tobacco smoke. 15077011

2004
dbSNP: rs1052133
rs1052133
OGG1 ; CAMK1
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung 		0.100 GeneticVariation BEFREE We therefore examined the association between single nucleotide polymorphisms (SNPs) in four genes (AKR1C3-Gln5His, NQO1-Pro187Ser, MnSOD-Val16Ala and OGG1-Ser326Cys) that play a role in the generation, prevention or repair of oxidative damage and lung cancer risk in a population-based, case-control study of 119 cases and 113 controls in Xuan Wei, China. 15284179

2004
dbSNP: rs1052133
rs1052133
OGG1 ; CAMK1
CUI: C0242379
Disease: Malignant neoplasm of lung
Malignant neoplasm of lung 		0.100 GeneticVariation BEFREE We therefore examined the association between single nucleotide polymorphisms (SNPs) in four genes (AKR1C3-Gln5His, NQO1-Pro187Ser, MnSOD-Val16Ala and OGG1-Ser326Cys) that play a role in the generation, prevention or repair of oxidative damage and lung cancer risk in a population-based, case-control study of 119 cases and 113 controls in Xuan Wei, China. 15284179

2004
dbSNP: rs1052133
rs1052133
OGG1 ; CAMK1
CUI: C1306460
Disease: Primary malignant neoplasm of lung
Primary malignant neoplasm of lung 		0.100 GeneticVariation BEFREE We therefore examined the association between single nucleotide polymorphisms (SNPs) in four genes (AKR1C3-Gln5His, NQO1-Pro187Ser, MnSOD-Val16Ala and OGG1-Ser326Cys) that play a role in the generation, prevention or repair of oxidative damage and lung cancer risk in a population-based, case-control study of 119 cases and 113 controls in Xuan Wei, China. 15284179

2004
dbSNP: rs1052133
rs1052133
OGG1 ; CAMK1
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach 		0.100 GeneticVariation BEFREE hOGG1 Ser326Cys polymorphism, interaction with environmental exposures, and gastric cancer risk in Japanese populations. 15596047

2004
dbSNP: rs1052133
rs1052133
OGG1 ; CAMK1
CUI: C0699791
Disease: Stomach Carcinoma
Stomach Carcinoma 		0.100 GeneticVariation BEFREE hOGG1 Ser326Cys polymorphism, interaction with environmental exposures, and gastric cancer risk in Japanese populations. 15596047

2004
dbSNP: rs1052133
rs1052133
OGG1 ; CAMK1
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis 		0.040 GeneticVariation BEFREE However, we cannot exclude the possibility that the OGG1 Ser326Cys and XRCC1 Arg194Trp polymorphisms play minor roles in lung carcinogenesis. 15840879

2005
dbSNP: rs1052133
rs1052133
OGG1 ; CAMK1
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung 		0.100 GeneticVariation BEFREE GSTP1 Ile105Val and hOGG1 Ser326Cys polymorphisms were not found to be risk factors of lung cancer in this study. 15896461

2005
dbSNP: rs1052133
rs1052133
OGG1 ; CAMK1
CUI: C0242379
Disease: Malignant neoplasm of lung
Malignant neoplasm of lung 		0.100 GeneticVariation BEFREE GSTP1 Ile105Val and hOGG1 Ser326Cys polymorphisms were not found to be risk factors of lung cancer in this study. 15896461

2005
dbSNP: rs1052133
rs1052133
OGG1 ; CAMK1
CUI: C1306460
Disease: Primary malignant neoplasm of lung
Primary malignant neoplasm of lung 		0.100 GeneticVariation BEFREE GSTP1 Ile105Val and hOGG1 Ser326Cys polymorphisms were not found to be risk factors of lung cancer in this study. 15896461

2005
dbSNP: rs1052133
rs1052133
OGG1 ; CAMK1
CUI: C4722085
Disease: Malignant neoplasm of colon and/or rectum
Malignant neoplasm of colon and/or rectum 		0.100 GeneticVariation BEFREE Carriers of the variant allele OGG1 Ser326Cys polymorphism had a lowered risk of colorectal cancer, OR=0.56 (95% confidence interval 0.33-0.95), while no association were found with risk of adenomas. 15946795

2005
dbSNP: rs1052133
rs1052133
OGG1 ; CAMK1
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		0.100 GeneticVariation BEFREE Carriers of the variant allele OGG1 Ser326Cys polymorphism had a lowered risk of colorectal cancer, OR=0.56 (95% confidence interval 0.33-0.95), while no association were found with risk of adenomas. 15946795

2005
dbSNP: rs1052133
rs1052133
OGG1 ; CAMK1
CUI: C0001430
Disease: Adenoma
Adenoma 		0.010 GeneticVariation BEFREE Carriers of the variant allele OGG1 Ser326Cys polymorphism had a lowered risk of colorectal cancer, OR=0.56 (95% confidence interval 0.33-0.95), while no association were found with risk of adenomas. 15946795

2005
dbSNP: rs1052133
rs1052133
OGG1 ; CAMK1
CUI: C1302401
Disease: Adenoma of large intestine
Adenoma of large intestine 		0.010 GeneticVariation BEFREE GPX Pro198Leu and OGG1 Ser326Cys polymorphisms and risk of development of colorectal adenomas and colorectal cancer. 15946795

2005
dbSNP: rs1052133
rs1052133
OGG1 ; CAMK1
CUI: C0007847
Disease: Malignant tumor of cervix
Malignant tumor of cervix 		0.020 GeneticVariation BEFREE Association of XRCC1 Arg399Gln and OGG1 Ser326Cys polymorphisms with the risk of cervical cancer in Japanese subjects. 15990162

2005
dbSNP: rs1052133
rs1052133
OGG1 ; CAMK1
CUI: C0302592
Disease: Cervix carcinoma
Cervix carcinoma 		0.020 GeneticVariation BEFREE Association of XRCC1 Arg399Gln and OGG1 Ser326Cys polymorphisms with the risk of cervical cancer in Japanese subjects. 15990162

2005