Source: CURATED ×
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7157
Gene Symbol: TP53
TP53 		P04637 tumor protein p53 Transcription factor 232 0.236 0.962 0.53 0.700 None 0.963 2 1 1990 2020
Entrez Id: 51741
Gene Symbol: WWOX
WWOX 		Q9NZC7 WW domain containing oxidoreductase Enzyme 39 0.453 0.808 1.2E-15 0.610 None 1.000 0 1 2004 2004
Entrez Id: 1956
Gene Symbol: EGFR
EGFR 		P00533 epidermal growth factor receptor Kinase 124 0.295 0.885 0.37 0.600 None 1.000 3 0 1988 2020
Entrez Id: 7048
Gene Symbol: TGFBR2
TGFBR2 		P37173 transforming growth factor beta receptor 2 Kinase 71 0.413 0.846 0.13 0.600 None 1.000 1 1 2000 2000
Entrez Id: 217
Gene Symbol: ALDH2
ALDH2 		P05091 aldehyde dehydrogenase 2 family member Enzyme 34 0.457 0.885 3.4E-10 0.500 None 0.982 1 2 1996 2020
Entrez Id: 125
Gene Symbol: ADH1B
ADH1B 		P00325 alcohol dehydrogenase 1B (class I), beta polypeptide Enzyme 27 0.502 0.846 9.9E-07 0.500 None 1.000 1 1 1997 2016
Entrez Id: 11178
Gene Symbol: LZTS1
LZTS1 		Q9Y250 leucine zipper tumor suppressor 1 7 0.633 0.385 0.95 0.500 None 0 0
Entrez Id: 6049
Gene Symbol: RNF6
RNF6 		Q9Y252 ring finger protein 6 7 0.656 0.615 1.4E-02 0.500 None 0 0
Entrez Id: 1630
Gene Symbol: DCC
DCC 		P43146 DCC netrin 1 receptor 21 0.471 0.808 0.99 0.500 None 0 0
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2 		P35354 prostaglandin-endoperoxide synthase 2 Enzyme 239 0.314 0.962 1.00 0.400 None 1.000 3 0 2000 2019
Entrez Id: 595
Gene Symbol: CCND1
CCND1 		P24385 cyclin D1 Enzyme modulator 96 0.344 0.923 0.89 0.400 None 0.962 1 0 1993 2019
Entrez Id: 406991
Gene Symbol: MIR21
MIR21 		microRNA 21 28 0.363 0.846 0.400 None 1.000 1 0 2011 2019
Entrez Id: 596
Gene Symbol: BCL2
BCL2 		P10415 BCL2 apoptosis regulator Signaling 141 0.291 0.885 0.56 0.400 None 1.000 1 0 1996 2020
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2 		P04626 erb-b2 receptor tyrosine kinase 2 Kinase 83 0.328 0.923 6.0E-03 0.400 None 0.944 1 0 1997 2019
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A 		P42771 Q8N726 cyclin dependent kinase inhibitor 2A 115 0.300 0.885 0.39 0.400 None 0.964 1 0 1994 2019
Entrez Id: 4233
Gene Symbol: MET
MET 		P08581 MET proto-oncogene, receptor tyrosine kinase Kinase 90 0.380 0.846 0.97 0.370 None 1.000 1 0 2006 2018
Entrez Id: 406937
Gene Symbol: MIR145
MIR145 		microRNA 145 32 0.431 0.846 0.370 None 1.000 1 0 2011 2020
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1 		P08183 ATP binding cassette subfamily B member 1 Transporter 84 0.344 0.885 1.3E-05 0.360 None 1.000 1 0 1994 2016
Entrez Id: 331
Gene Symbol: XIAP
XIAP 		P98170 X-linked inhibitor of apoptosis Enzyme modulator 15 0.447 0.808 0.92 0.350 None 1.000 1 0 2007 2019
Entrez Id: 4323
Gene Symbol: MMP14
MMP14 		P50281 matrix metallopeptidase 14 Enzyme 21 0.447 0.769 1.00 0.340 None 1.000 1 0 2000 2014
Entrez Id: 864
Gene Symbol: RUNX3
RUNX3 		Q13761 RUNX family transcription factor 3 Transcription factor 27 0.459 0.731 0.84 0.340 None 0.800 1 0 2007 2017
Entrez Id: 3958
Gene Symbol: LGALS3
LGALS3 		P17931 galectin 3 Signaling 26 0.392 0.846 2.3E-05 0.340 None 0.750 1 0 2007 2018
Entrez Id: 5052
Gene Symbol: PRDX1
PRDX1 		Q06830 peroxiredoxin 1 Enzyme 18 0.485 0.846 7.7E-10 0.340 None 0.600 1 0 2005 2017
Entrez Id: 3791
Gene Symbol: KDR
KDR 		P35968 kinase insert domain receptor Kinase 53 0.378 0.885 1.00 0.330 None 1.000 1 0 2011 2019
Entrez Id: 7001
Gene Symbol: PRDX2
PRDX2 		P32119 peroxiredoxin 2 Enzyme 25 0.474 0.885 8.7E-02 0.330 None 1.000 1 0 2005 2019