Source: CURATED ×
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.700 Biomarker disease CTD_human Genomic landscape of cutaneous T cell lymphoma. 26192916 2015
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.700 Biomarker disease CTD_human Low expression of Bax predicts poor prognosis in patients with locally advanced esophageal cancer treated with definitive chemoradiotherapy. 17634542 2007
Entrez Id: 51741
Gene Symbol: WWOX
WWOX 		0.610 Biomarker disease CTD_human
Entrez Id: 51741
Gene Symbol: WWOX
WWOX 		0.610 CausalMutation disease CGI
Entrez Id: 1956
Gene Symbol: EGFR
EGFR 		0.600 Biomarker disease CTD_human Targeting the human EGFR family in esophagogastric cancer. 21468131 2011
Entrez Id: 1956
Gene Symbol: EGFR
EGFR 		0.600 Biomarker disease CTD_human The EGFR CA repeat genetic polymorphism may act as a valuable molecular predictor of clinical outcome of esophageal cancer after CCRT and esophagectomy, especially in those with good response to CCRT. 21298351 2011
Entrez Id: 1956
Gene Symbol: EGFR
EGFR 		0.600 Biomarker disease CTD_human MET amplification identifies a small and aggressive subgroup of esophagogastric adenocarcinoma with evidence of responsiveness to crizotinib. 22042947 2011
Entrez Id: 7048
Gene Symbol: TGFBR2
TGFBR2 		0.600 Biomarker disease CTD_human A dominant negative mutation of transforming growth factor-beta receptor type II gene in microsatellite stable oesophageal carcinoma. 10789724 2000
Entrez Id: 7048
Gene Symbol: TGFBR2
TGFBR2 		0.600 CausalMutation disease CGI
Entrez Id: 1956
Gene Symbol: EGFR
EGFR 		0.600 CausalMutation disease CGI
Entrez Id: 125
Gene Symbol: ADH1B
ADH1B 		0.500 Biomarker disease CTD_human Multiple ADH genes are associated with upper aerodigestive cancers. 18500343 2008
Entrez Id: 217
Gene Symbol: ALDH2
ALDH2 		0.500 Biomarker disease CTD_human These results suggest that to help lower their risk for esophageal cancer, persons with the ALDH2*2 allele should be encouraged to reduce their consumption of alcoholic beverages. 8850269 1996
Entrez Id: 6049
Gene Symbol: RNF6
RNF6 		0.500 Biomarker disease CTD_human
Entrez Id: 6049
Gene Symbol: RNF6
RNF6 		0.500 CausalMutation disease CGI
Entrez Id: 1630
Gene Symbol: DCC
DCC 		0.500 Biomarker disease CTD_human
Entrez Id: 1630
Gene Symbol: DCC
DCC 		0.500 CausalMutation disease CGI
Entrez Id: 11178
Gene Symbol: LZTS1
LZTS1 		0.500 Biomarker disease CTD_human
Entrez Id: 11178
Gene Symbol: LZTS1
LZTS1 		0.500 CausalMutation disease CGI
Entrez Id: 406991
Gene Symbol: MIR21
MIR21 		0.400 Biomarker disease CTD_human Using 98 formalin-fixed, paraffin-embedded samples obtained from patients with esophageal cancer who had received preoperative chemotherapy followed by surgery, we measured expression levels of several miRNAs that are considered to be involved in the regulation of stem cell function (e.g., let-7a, let-7g, miR-21, miR-134, miR-145, miR-155, miR-200c, miR-203, and miR-296) by real-time reverse transcriptase PCR. 21248297 2011
Entrez Id: 596
Gene Symbol: BCL2
BCL2 		0.400 Biomarker disease CTD_human Association between polymorphisms in cancer-related genes and early onset of esophageal adenocarcinoma. 21472143 2011
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2 		0.400 Biomarker disease CTD_human MET amplification identifies a small and aggressive subgroup of esophagogastric adenocarcinoma with evidence of responsiveness to crizotinib. 22042947 2011
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A 		0.400 Biomarker disease CTD_human Progressive silencing of p14ARF in oesophageal adenocarcinoma. 18410530 2009
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2 		0.400 Biomarker disease CTD_human We evaluated the effects of specific COX-2 inhibitors, NS-398 and nimesulide, on cell lines of both histological types of OC. 17707579 2007
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2 		0.400 Biomarker disease CTD_human We analyzed the association of COX-2 mRNA and protein expression with histomorphologic response to neoadjuvant radiochemotherapy in esophageal cancer. 16322294 2005
Entrez Id: 595
Gene Symbol: CCND1
CCND1 		0.400 Biomarker disease CTD_human Whereas L2D1(+) mice exhibit a histologic phenotype of oral-esophageal dysplasia, the combination of cyclin D1 expression and p53 deficiency results in invasive oral-esophageal cancer. 12235107 2002