Source: CURATED ×
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 673
Gene Symbol: BRAF
BRAF 		P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 115 0.319 0.846 1.00 0.700 None 1.000 1 12 2002 2019
Entrez Id: 3845
Gene Symbol: KRAS
KRAS 		P01116 KRAS proto-oncogene, GTPase Enzyme modulator 164 0.320 0.923 7.9E-04 0.700 None 0.980 0 4 1985 2020
Entrez Id: 5002
Gene Symbol: SLC22A18
SLC22A18 		Q96BI1 solute carrier family 22 member 18 Transporter 13 0.595 0.692 6.5E-06 0.600 None 1.000 1 1 1998 1998
Entrez Id: 2067
Gene Symbol: ERCC1
ERCC1 		P07992 ERCC excision repair 1, endonuclease non-catalytic subunit Enzyme 42 0.445 0.846 1.6E-07 0.600 None 0.949 0 0 2005 2019
Entrez Id: 1956
Gene Symbol: EGFR
EGFR 		P00533 epidermal growth factor receptor Kinase 124 0.295 0.885 0.37 0.500 None 0.985 0 2 1988 2020
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA 		P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 98 0.292 0.923 1.00 0.500 None 0.972 0 2 2002 2019
Entrez Id: 5071
Gene Symbol: PRKN
PRKN 		O60260 parkin RBR E3 ubiquitin protein ligase Enzyme 42 0.431 0.846 6.9E-07 0.500 moderate 1.000 0 1 2011 2020
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2 		P51587 BRCA2 DNA repair associated Nucleic acid binding 56 0.379 0.846 2.4E-25 0.500 None 0.846 0 2 2000 2018
Entrez Id: 7157
Gene Symbol: TP53
TP53 		P04637 tumor protein p53 Transcription factor 232 0.236 0.962 0.53 0.500 None 0.942 0 1 1989 2020
Entrez Id: 8626
Gene Symbol: TP63
TP63 		Q9H3D4 tumor protein p63 Transcription factor 56 0.362 0.769 1.00 0.500 None 0.958 0 2 1999 2019
Entrez Id: 2074
Gene Symbol: ERCC6
ERCC6 		P0DP91 Q03468 ERCC excision repair 6, chromatin remodeling factor 36 0.507 0.808 5.2E-22 0.430 limited 1.000 0 4 2000 2009
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2 		P04626 erb-b2 receptor tyrosine kinase 2 Kinase 83 0.328 0.923 6.0E-03 0.400 None 0.972 1 1 1989 2020
Entrez Id: 5728
Gene Symbol: PTEN
PTEN 		P60484 phosphatase and tensin homolog Enzyme 182 0.305 0.923 0.26 0.400 None 0.979 0 0 1985 2019
Entrez Id: 4915
Gene Symbol: NTRK2
NTRK2 		Q16620 neurotrophic receptor tyrosine kinase 2 Kinase 58 0.479 0.808 1.00 0.350 None 1.000 0 1 2013 2019
Entrez Id: 2042
Gene Symbol: EPHA3
EPHA3 		P29320 EPH receptor A3 Kinase 11 0.497 0.692 1.2E-05 0.350 None 1.000 0 1 1999 2018
Entrez Id: 253260
Gene Symbol: RICTOR
RICTOR 		Q6R327 RPTOR independent companion of MTOR complex 2 3 0.592 0.615 1.00 0.330 None 1.000 0 0 2015 2017
Entrez Id: 5885
Gene Symbol: RAD21
RAD21 		O60216 RAD21 cohesin complex component 17 0.528 0.846 1.00 0.310 None 1.000 0 0 2019 2019
Entrez Id: 4916
Gene Symbol: NTRK3
NTRK3 		Q16288 neurotrophic receptor tyrosine kinase 3 Kinase 27 0.522 0.692 1.00 0.310 None 1.000 0 0 2017 2017
Entrez Id: 3659
Gene Symbol: IRF1
IRF1 		P10914 interferon regulatory factor 1 Transcription factor 14 0.468 0.769 0.99 0.310 limited 1.000 0 0 2018 2018
Entrez Id: 283106
Gene Symbol: CSNK2A3
CSNK2A3 		Q8NEV1 casein kinase 2 alpha 3 Kinase 1 0.821 0.077 2.1E-10 0.310 None 1.000 0 1 2010 2010
Entrez Id: 25878
Gene Symbol: MXRA5
MXRA5 		Q9NR99 matrix remodeling associated 5 2 0.839 0.192 4.3E-02 0.300 None 1.000 1 5 2012 2012
Entrez Id: 6016
Gene Symbol: RIT1
RIT1 		Q92963 Ras like without CAAX 1 Enzyme modulator 12 0.527 0.808 0.13 0.300 None 0 0
Entrez Id: 894
Gene Symbol: CCND2
CCND2 		P30279 cyclin D2 Enzyme modulator 42 0.477 0.808 0.99 0.300 None 0 0