Source: CURATED ×
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs121913530
rs121913530
A 0.880 CausalMutation CLINVAR

dbSNP: rs121913530
rs121913530
0.880 GeneticVariation UNIPROT

dbSNP: rs1051730
rs1051730
T 0.800 GeneticVariation GWASCAT Identification of susceptibility pathways for the role of chromosome 15q25.1 in modifying lung cancer risk. 30104567

2018

dbSNP: rs121909071
rs121909071
0.800 GeneticVariation UNIPROT Non-small cell lung cancer and precision medicine: a model for the incorporation of genomic features into clinical trial design. 24846033

2014

dbSNP: rs121909071
rs121909071
0.800 GeneticVariation UNIPROT Molecular testing for selection of patients with lung cancer for epidermal growth factor receptor and anaplastic lymphoma kinase tyrosine kinase inhibitors: American Society of Clinical Oncology endorsement of the College of American Pathologists/International Association for the study of lung cancer/association for molecular pathology guideline. 25311215

2014

dbSNP: rs121909071
rs121909071
0.800 GeneticVariation UNIPROT Guideline Recommendations for Testing of ALK Gene Rearrangement in Lung Cancer: A Proposal of the Korean Cardiopulmonary Pathology Study Group. 24627688

2014

dbSNP: rs121913351
rs121913351
0.800 GeneticVariation UNIPROT Guideline Recommendations for Testing of ALK Gene Rearrangement in Lung Cancer: A Proposal of the Korean Cardiopulmonary Pathology Study Group. 24627688

2014

dbSNP: rs121913351
rs121913351
0.800 GeneticVariation UNIPROT Non-small cell lung cancer and precision medicine: a model for the incorporation of genomic features into clinical trial design. 24846033

2014

dbSNP: rs121913351
rs121913351
0.800 GeneticVariation UNIPROT Molecular testing for selection of patients with lung cancer for epidermal growth factor receptor and anaplastic lymphoma kinase tyrosine kinase inhibitors: American Society of Clinical Oncology endorsement of the College of American Pathologists/International Association for the study of lung cancer/association for molecular pathology guideline. 25311215

2014

dbSNP: rs121913529
rs121913529
T 0.800 GeneticVariation CLINVAR Prospective enterprise-level molecular genotyping of a cohort of cancer patients. 25157968

2014

dbSNP: rs121913529
rs121913529
T 0.800 GeneticVariation CLINVAR Phase II study of the GI-4000 KRAS vaccine after curative therapy in patients with stage I-III lung adenocarcinoma harboring a KRAS G12C, G12D, or G12V mutation. 25044103

2014

dbSNP: rs121909071
rs121909071
0.800 GeneticVariation UNIPROT Guideline Recommendations for EGFR Mutation Testing in Lung Cancer: Proposal of the Korean Cardiopulmonary Pathology Study Group. 23667368

2013

dbSNP: rs121909071
rs121909071
0.800 GeneticVariation UNIPROT Molecular testing guideline for selection of lung cancer patients for EGFR and ALK tyrosine kinase inhibitors: guideline from the College of American Pathologists, International Association for the Study of Lung Cancer, and Association for Molecular Pathology. 23562183

2013

dbSNP: rs121913351
rs121913351
0.800 GeneticVariation UNIPROT Guideline Recommendations for EGFR Mutation Testing in Lung Cancer: Proposal of the Korean Cardiopulmonary Pathology Study Group. 23667368

2013

dbSNP: rs121913351
rs121913351
A 0.800 CausalMutation CLINVAR Clinical, pathologic, and biologic features associated with BRAF mutations in non-small cell lung cancer. 23833300

2013

dbSNP: rs121913351
rs121913351
0.800 GeneticVariation UNIPROT Molecular testing guideline for selection of lung cancer patients for EGFR and ALK tyrosine kinase inhibitors: guideline from the College of American Pathologists, International Association for the Study of Lung Cancer, and Association for Molecular Pathology. 23562183

2013

dbSNP: rs13181
rs13181
C 0.800 GeneticVariation GWASCAT Genome-wide association study reveals novel genetic determinants of DNA repair capacity in lung cancer. 23108145

2013

dbSNP: rs121913351
rs121913351
A 0.800 CausalMutation CLINVAR Kinase-impaired BRAF mutations in lung cancer confer sensitivity to dasatinib. 22649091

2012

dbSNP: rs121913529
rs121913529
T 0.800 GeneticVariation CLINVAR Molecular epidemiology of EGFR and KRAS mutations in 3,026 lung adenocarcinomas: higher susceptibility of women to smoking-related KRAS-mutant cancers. 23014527

2012

dbSNP: rs2736100
rs2736100
G 0.800 GeneticVariation GWASCAT Genome-wide association analysis identifies new lung cancer susceptibility loci in never-smoking women in Asia. 23143601

2012

dbSNP: rs121913351
rs121913351
A 0.800 CausalMutation CLINVAR Clinical characteristics of patients with lung adenocarcinomas harboring BRAF mutations. 21483012

2011

dbSNP: rs2736100
rs2736100
C 0.800 GeneticVariation GWASCAT The combined analyses identified six well-replicated SNPs with independent effects and significant lung cancer associations (P < 5.0 × 10(-8)) located in TP63 (rs4488809 at 3q28, P = 7.2 × 10(-26)), TERT-CLPTM1L (rs465498 and rs2736100 at 5p15.33, P = 1.2 × 10(-20) and P = 1.0 × 10(-27), respectively), MIPEP-TNFRSF19 (rs753955 at 13q12.12, P = 1.5 × 10(-12)) and MTMR3-HORMAD2-LIF (rs17728461 and rs36600 at 22q12.2, P = 1.1 × 10(-11) and P = 6.2 × 10(-13), respectively). 21725308

2011

dbSNP: rs121913351
rs121913351
A 0.800 CausalMutation CLINVAR Alterations in genes of the EGFR signaling pathway and their relationship to EGFR tyrosine kinase inhibitor sensitivity in lung cancer cell lines. 19238210

2009

dbSNP: rs8034191
rs8034191
0.800 GeneticVariation GWASCAT A meta-analysis provided increased support that variation at 15q25.1 (rs8034191; P = 3.24 x 10(-26)), 5p15.33 (rs4975616; P = 2.99 x 10(-9)), and 6p21.33 (rs3117582; P = 4.46 x 10(-10)) influences lung cancer risk. 19654303

2009

dbSNP: rs1051730
rs1051730
A 0.800 GeneticVariation GWASCAT Lung cancer susceptibility locus at 5p15.33. 18978790

2008