Source: CURATED ×
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A 		0.800 Biomarker group CTD_human Progressive silencing of p14ARF in oesophageal adenocarcinoma. 18410530 2009
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A 		0.800 GeneticVariation group UNIPROT
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.600 Biomarker group CTD_human Genomic landscape of cutaneous T cell lymphoma. 26192916 2015
Entrez Id: 1956
Gene Symbol: EGFR
EGFR 		0.600 Biomarker group CTD_human Targeting the human EGFR family in esophagogastric cancer. 21468131 2011
Entrez Id: 1956
Gene Symbol: EGFR
EGFR 		0.600 Biomarker group CTD_human MET amplification identifies a small and aggressive subgroup of esophagogastric adenocarcinoma with evidence of responsiveness to crizotinib. 22042947 2011
Entrez Id: 1956
Gene Symbol: EGFR
EGFR 		0.600 Biomarker group CTD_human The EGFR CA repeat genetic polymorphism may act as a valuable molecular predictor of clinical outcome of esophageal cancer after CCRT and esophagectomy, especially in those with good response to CCRT. 21298351 2011
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2 		0.600 Biomarker group CTD_human Cyclooxygenase-2 inhibitors demonstrate anti-proliferative effects in oesophageal cancer cells by prostaglandin E(2)-independent mechanisms. 17707579 2007
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.600 Biomarker group CTD_human Low expression of Bax predicts poor prognosis in patients with locally advanced esophageal cancer treated with definitive chemoradiotherapy. 17634542 2007
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2 		0.600 Biomarker group CTD_human We analyzed the association of COX-2 mRNA and protein expression with histomorphologic response to neoadjuvant radiochemotherapy in esophageal cancer. 16322294 2005
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2 		0.600 Biomarker group CTD_human Selective inhibition of cyclooxygenase-2 suppresses growth and induces apoptosis in human esophageal adenocarcinoma cells. 11059772 2000
Entrez Id: 1956
Gene Symbol: EGFR
EGFR 		0.600 CausalMutation group CGI
Entrez Id: 51741
Gene Symbol: WWOX
WWOX 		0.600 CausalMutation group CGI
Entrez Id: 51741
Gene Symbol: WWOX
WWOX 		0.600 Biomarker group CTD_human
Entrez Id: 11178
Gene Symbol: LZTS1
LZTS1 		0.510 CausalMutation group CGI
Entrez Id: 1630
Gene Symbol: DCC
DCC 		0.510 CausalMutation group CGI
Entrez Id: 11178
Gene Symbol: LZTS1
LZTS1 		0.510 Biomarker group CTD_human
Entrez Id: 1630
Gene Symbol: DCC
DCC 		0.510 Biomarker group CTD_human
Entrez Id: 125
Gene Symbol: ADH1B
ADH1B 		0.500 Biomarker group CTD_human Multiple ADH genes are associated with upper aerodigestive cancers. 18500343 2008
Entrez Id: 7048
Gene Symbol: TGFBR2
TGFBR2 		0.500 Biomarker group CTD_human A dominant negative mutation of transforming growth factor-beta receptor type II gene in microsatellite stable oesophageal carcinoma. 10789724 2000
Entrez Id: 217
Gene Symbol: ALDH2
ALDH2 		0.500 Biomarker group CTD_human These results suggest that to help lower their risk for esophageal cancer, persons with the ALDH2*2 allele should be encouraged to reduce their consumption of alcoholic beverages. 8850269 1996
Entrez Id: 6049
Gene Symbol: RNF6
RNF6 		0.500 Biomarker group CTD_human
Entrez Id: 7048
Gene Symbol: TGFBR2
TGFBR2 		0.500 CausalMutation group CGI
Entrez Id: 6049
Gene Symbol: RNF6
RNF6 		0.500 CausalMutation group CGI
Entrez Id: 841
Gene Symbol: CASP8
CASP8 		0.410 Biomarker group CTD_human Association between polymorphisms in cancer-related genes and early onset of esophageal adenocarcinoma. 21472143 2011
Entrez Id: 841
Gene Symbol: CASP8
CASP8 		0.410 Biomarker group CTD_human A six-nucleotide insertion-deletion polymorphism in the CASP8 promoter is associated with susceptibility to multiple cancers. 17450141 2007