Source: CURATED ×
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs2274223
rs2274223
PLCE1
0.900 GeneticVariation GWASDB Genotypic variants at 2q33 and risk of esophageal squamous cell carcinoma in China: a meta-analysis of genome-wide association studies. 22323360

2012
dbSNP: rs2274223
rs2274223
PLCE1
G 0.900 GeneticVariation GWASCAT Genome-wide association study identifies three new susceptibility loci for esophageal squamous-cell carcinoma in Chinese populations. 21642993

2011
dbSNP: rs2274223
rs2274223
PLCE1
0.900 GeneticVariation GWASDB Genome-wide association study of esophageal squamous cell carcinoma in Chinese subjects identifies susceptibility loci at PLCE1 and C20orf54. 20729853

2010
dbSNP: rs671
rs671
ALDH2
0.880 GeneticVariation GWASDB Strong interaction between the effects of alcohol consumption and smoking on oesophageal squamous cell carcinoma among individuals with ADH1B and/or ALDH2 risk alleles. 20833657

2010
dbSNP: rs671
rs671
ALDH2
A 0.880 GeneticVariation GWASCAT Functional variants in ADH1B and ALDH2 coupled with alcohol and smoking synergistically enhance esophageal cancer risk. 19698717

2009
dbSNP: rs1229984
rs1229984
ADH1B
0.840 GeneticVariation GWASDB Strong interaction between the effects of alcohol consumption and smoking on oesophageal squamous cell carcinoma among individuals with ADH1B and/or ALDH2 risk alleles. 20833657

2010
dbSNP: rs1229984
rs1229984
ADH1B
G 0.840 GeneticVariation GWASCAT Functional variants in ADH1B and ALDH2 coupled with alcohol and smoking synergistically enhance esophageal cancer risk. 19698717

2009
dbSNP: rs3765524
rs3765524
PLCE1
0.820 GeneticVariation GWASDB Genotypic variants at 2q33 and risk of esophageal squamous cell carcinoma in China: a meta-analysis of genome-wide association studies. 22323360

2012
dbSNP: rs3765524
rs3765524
PLCE1
T 0.820 GeneticVariation GWASDB A shared susceptibility locus in PLCE1 at 10q23 for gastric adenocarcinoma and esophageal squamous cell carcinoma. 20729852

2010
dbSNP: rs3765524
rs3765524
PLCE1
T 0.820 GeneticVariation GWASCAT A shared susceptibility locus in PLCE1 at 10q23 for gastric adenocarcinoma and esophageal squamous cell carcinoma. 20729852

2010
dbSNP: rs738722
rs738722
CHEK2
T 0.810 GeneticVariation GWASCAT A shared susceptibility locus in PLCE1 at 10q23 for gastric adenocarcinoma and esophageal squamous cell carcinoma. 20729852

2010
dbSNP: rs738722
rs738722
CHEK2
T 0.810 GeneticVariation GWASDB A shared susceptibility locus in PLCE1 at 10q23 for gastric adenocarcinoma and esophageal squamous cell carcinoma. 20729852

2010
dbSNP: rs1042026
rs1042026
ADH1B
0.800 GeneticVariation GWASDB Genome-wide association analyses of esophageal squamous cell carcinoma in Chinese identify multiple susceptibility loci and gene-environment interactions. 22960999

2012
dbSNP: rs1042026
rs1042026
ADH1B
0.800 GeneticVariation GWASCAT Genome-wide association analyses of esophageal squamous cell carcinoma in Chinese identify multiple susceptibility loci and gene-environment interactions. 22960999

2012
dbSNP: rs17450420
rs17450420 		0.800 GeneticVariation GWASDB Genome-wide association analyses of esophageal squamous cell carcinoma in Chinese identify multiple susceptibility loci and gene-environment interactions. 22960999

2012
dbSNP: rs17450420
rs17450420 		0.800 GeneticVariation GWASCAT Genome-wide association analyses of esophageal squamous cell carcinoma in Chinese identify multiple susceptibility loci and gene-environment interactions. 22960999

2012
dbSNP: rs17761864
rs17761864
SMG6
A 0.800 GeneticVariation GWASDB Genome-wide association analyses of esophageal squamous cell carcinoma in Chinese identify multiple susceptibility loci and gene-environment interactions. 22960999

2012
dbSNP: rs17761864
rs17761864
SMG6
A 0.800 GeneticVariation GWASCAT Genome-wide association analyses of esophageal squamous cell carcinoma in Chinese identify multiple susceptibility loci and gene-environment interactions. 22960999

2012
dbSNP: rs2239612
rs2239612
ST6GAL1
T 0.800 GeneticVariation GWASDB Genome-wide association analyses of esophageal squamous cell carcinoma in Chinese identify multiple susceptibility loci and gene-environment interactions. 22960999

2012
dbSNP: rs2239612
rs2239612
ST6GAL1
T 0.800 GeneticVariation GWASCAT Genome-wide association analyses of esophageal squamous cell carcinoma in Chinese identify multiple susceptibility loci and gene-environment interactions. 22960999

2012
dbSNP: rs2239815
rs2239815
XBP1
T 0.800 GeneticVariation GWASDB Genome-wide association analyses of esophageal squamous cell carcinoma in Chinese identify multiple susceptibility loci and gene-environment interactions. 22960999

2012
dbSNP: rs2239815
rs2239815
XBP1
T 0.800 GeneticVariation GWASCAT Genome-wide association analyses of esophageal squamous cell carcinoma in Chinese identify multiple susceptibility loci and gene-environment interactions. 22960999

2012
dbSNP: rs2847281
rs2847281
PTPN2
C 0.800 GeneticVariation GWASCAT Genome-wide association analyses of esophageal squamous cell carcinoma in Chinese identify multiple susceptibility loci and gene-environment interactions. 22960999

2012
dbSNP: rs2847281
rs2847281
PTPN2
C 0.800 GeneticVariation GWASDB Genome-wide association analyses of esophageal squamous cell carcinoma in Chinese identify multiple susceptibility loci and gene-environment interactions. 22960999

2012
dbSNP: rs3805322
rs3805322
ADH4 ; LOC100507053
0.800 GeneticVariation GWASDB Genome-wide association analyses of esophageal squamous cell carcinoma in Chinese identify multiple susceptibility loci and gene-environment interactions. 22960999

2012