Disease: Fanconi Anemia
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
EXO1 Q9UQ84 exonuclease 1 Enzyme 8.1E-13 0.578 0.692
DNA2 P51530 DNA replication helicase/nuclease 2 1.3E-18 0.626 0.731
FEN1 P39748 flap structure-specific endonuclease 1 Enzyme 4.8E-05 0.550 0.731
BRIP1 Q9BX63 BRCA1 interacting protein C-terminal helicase 1 Enzyme 6.2E-17 0.507 0.731
XRCC6 P12956 X-ray repair cross complementing 6 Enzyme 1.00 0.552 0.769
POLD1 P28340 DNA polymerase delta 1, catalytic subunit 2.4E-06 0.507 0.769
NEIL1 Q96FI4 nei like DNA glycosylase 1 5.0E-07 0.623 0.769
BLM P54132 BLM RecQ like helicase 1.5E-15 0.535 0.808
H2AX P16104 H2A.X variant histone Nucleic acid binding 0.18 0.484 0.808
MLH1 P40692 mutL homolog 1 Nucleic acid binding 3.4E-05 0.399 0.808
MRE11 P49959 MRE11 homolog, double strand break repair nuclease 1.3E-12 0.527 0.808
NBN O60934 nibrin Nucleic acid binding 2.2E-16 0.467 0.808
WRN Q14191 WRN RecQ like helicase Enzyme 2.6E-34 0.524 0.808
XRCC5 P13010 X-ray repair cross complementing 5 Enzyme 1.00 0.554 0.808
RECQL4 O94761 RecQ like helicase 4 Enzyme 3.3E-35 0.496 0.808
CDC42 P60953 cell division cycle 42 Enzyme modulator 0.79 0.458 0.846
ERCC1 P07992 ERCC excision repair 1, endonuclease non-catalytic subunit Enzyme 1.6E-07 0.445 0.846
ERCC4 Q92889 ERCC excision repair 4, endonuclease catalytic subunit Enzyme 1.4E-12 0.468 0.846
INSR P06213 insulin receptor Kinase 3.6E-05 0.432 0.846
MECP2 P51608 methyl-CpG binding protein 2 Epigenetic regulator 0.89 0.414 0.846
PCNA P12004 proliferating cell nuclear antigen Nucleic acid binding 0.98 0.382 0.846
RAD51 Q06609 RAD51 recombinase 2.7E-02 0.447 0.846
ATM Q13315 ATM serine/threonine kinase Kinase 5.6E-47 0.374 0.885
FANCD2 Q9BXW9 FA complementation group D2 1.1E-30 0.479 0.885
MTOR P42345 mechanistic target of rapamycin kinase Kinase 1.00 0.343 0.885