Disease: Fanconi Anemia
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962
TGFB1 P01137 transforming growth factor beta 1 Signaling 3.7E-02 0.287 0.962
MAPK1 P28482 mitogen-activated protein kinase 1 Kinase 1.00 0.330 0.923
MTOR P42345 mechanistic target of rapamycin kinase Kinase 1.00 0.343 0.885
PPARG P37231 peroxisome proliferator activated receptor gamma Nuclear receptor 2.9E-02 0.358 0.885
CAT P04040 catalase Enzyme 1.6E-10 0.359 0.962
ICAM1 P05362 intercellular adhesion molecule 1 3.5E-02 0.364 0.962
FN1 P02751 fibronectin 1 Signaling 1.4E-03 0.365 0.962
BRCA1 P38398 BRCA1 DNA repair associated Enzyme 9.2E-29 0.367 0.923
ATM Q13315 ATM serine/threonine kinase Kinase 5.6E-47 0.374 0.885
MAPK14 Q16539 mitogen-activated protein kinase 14 Kinase 0.37 0.379 0.923
PCNA P12004 proliferating cell nuclear antigen Nucleic acid binding 0.98 0.382 0.846
PARP1 P09874 poly(ADP-ribose) polymerase 1 3.3E-04 0.389 0.923
AIMP2 Q13155 aminoacyl tRNA synthetase complex interacting multifunctional protein 2 8.0E-03 0.393 0.923
CRK P46108 CRK proto-oncogene, adaptor protein 0.96 0.394 0.923
GRAP2 O75791 GRB2 related adaptor protein 2 1.5E-04 0.394 0.923
AHSA1 O95433 activator of HSP90 ATPase activity 1 1.00 0.396 0.923
POLDIP2 Q9Y2S7 DNA polymerase delta interacting protein 2 0.41 0.396 0.923
RNF19A Q9NV58 ring finger protein 19A, RBR E3 ubiquitin protein ligase Enzyme 2.5E-02 0.397 0.923
MLH1 P40692 mutL homolog 1 Nucleic acid binding 3.4E-05 0.399 0.808
MECP2 P51608 methyl-CpG binding protein 2 Epigenetic regulator 0.89 0.414 0.846
RAC1 P63000 Rac family small GTPase 1 Enzyme modulator 0.76 0.429 0.962
ABL1 P00519 ABL proto-oncogene 1, non-receptor tyrosine kinase Kinase 1.00 0.432 0.923
INSR P06213 insulin receptor Kinase 3.6E-05 0.432 0.846