Disease: Fanconi Anemia
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
NBN O60934 nibrin Nucleic acid binding 2.2E-16 0.467 0.808
GRAP2 O75791 GRB2 related adaptor protein 2 1.5E-04 0.394 0.923
RECQL4 O94761 RecQ like helicase 4 Enzyme 3.3E-35 0.496 0.808
AHSA1 O95433 activator of HSP90 ATPase activity 1 1.00 0.396 0.923
ABL1 P00519 ABL proto-oncogene 1, non-receptor tyrosine kinase Kinase 1.00 0.432 0.923
TGFB1 P01137 transforming growth factor beta 1 Signaling 3.7E-02 0.287 0.962
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962
GYPA P02724 glycophorin A (MNS blood group) 1.1E-03 0.538 0.885
FN1 P02751 fibronectin 1 Signaling 1.4E-03 0.365 0.962
CAT P04040 catalase Enzyme 1.6E-10 0.359 0.962
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
ICAM1 P05362 intercellular adhesion molecule 1 3.5E-02 0.364 0.962
INSR P06213 insulin receptor Kinase 3.6E-05 0.432 0.846
ERCC1 P07992 ERCC excision repair 1, endonuclease non-catalytic subunit Enzyme 1.6E-07 0.445 0.846
PARP1 P09874 poly(ADP-ribose) polymerase 1 3.3E-04 0.389 0.923
PCNA P12004 proliferating cell nuclear antigen Nucleic acid binding 0.98 0.382 0.846
XRCC6 P12956 X-ray repair cross complementing 6 Enzyme 1.00 0.552 0.769
XRCC5 P13010 X-ray repair cross complementing 5 Enzyme 1.00 0.554 0.808
H2AX P16104 H2A.X variant histone Nucleic acid binding 0.18 0.484 0.808
POLD1 P28340 DNA polymerase delta 1, catalytic subunit 2.4E-06 0.507 0.769
MAPK1 P28482 mitogen-activated protein kinase 1 Kinase 1.00 0.330 0.923
PPARG P37231 peroxisome proliferator activated receptor gamma Nuclear receptor 2.9E-02 0.358 0.885
BRCA1 P38398 BRCA1 DNA repair associated Enzyme 9.2E-29 0.367 0.923
FEN1 P39748 flap structure-specific endonuclease 1 Enzyme 4.8E-05 0.550 0.731
MLH1 P40692 mutL homolog 1 Nucleic acid binding 3.4E-05 0.399 0.808