Gene: MSH6 ×
Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1060502926
rs1060502926
MSH6 ; FBXO11
C 0.700 GeneticVariation CLINVAR Germline MSH6 mutations are more prevalent in endometrial cancer patient cohorts than hereditary non polyposis colorectal cancer cohorts. 18269114

2008
dbSNP: rs1060502926
rs1060502926
MSH6 ; FBXO11
C 0.700 GeneticVariation CLINVAR Application of a 5-tiered scheme for standardized classification of 2,360 unique mismatch repair gene variants in the InSiGHT locus-specific database. 24362816

2014
dbSNP: rs1064794075
rs1064794075
MSH6
AG 0.700 GeneticVariation CLINVAR Application of a 5-tiered scheme for standardized classification of 2,360 unique mismatch repair gene variants in the InSiGHT locus-specific database. 24362816

2014
dbSNP: rs1064794075
rs1064794075
MSH6
AG 0.700 GeneticVariation CLINVAR Germline MSH6 mutations are more prevalent in endometrial cancer patient cohorts than hereditary non polyposis colorectal cancer cohorts. 18269114

2008
dbSNP: rs1114167723
rs1114167723
MSH6 ; FBXO11
T 0.700 GeneticVariation CLINVAR Application of a 5-tiered scheme for standardized classification of 2,360 unique mismatch repair gene variants in the InSiGHT locus-specific database. 24362816

2014
dbSNP: rs1114167723
rs1114167723
MSH6 ; FBXO11
T 0.700 GeneticVariation CLINVAR Germline MSH6 mutations are more prevalent in endometrial cancer patient cohorts than hereditary non polyposis colorectal cancer cohorts. 18269114

2008
dbSNP: rs1114167725
rs1114167725
MSH6 ; FBXO11
G 0.700 GeneticVariation CLINVAR Application of a 5-tiered scheme for standardized classification of 2,360 unique mismatch repair gene variants in the InSiGHT locus-specific database. 24362816

2014
dbSNP: rs1114167725
rs1114167725
MSH6 ; FBXO11
G 0.700 GeneticVariation CLINVAR Germline MSH6 mutations are more prevalent in endometrial cancer patient cohorts than hereditary non polyposis colorectal cancer cohorts. 18269114

2008
dbSNP: rs1553331242
rs1553331242
MSH6 ; FBXO11
C 0.700 GeneticVariation CLINVAR Application of a 5-tiered scheme for standardized classification of 2,360 unique mismatch repair gene variants in the InSiGHT locus-specific database. 24362816

2014
dbSNP: rs1553331242
rs1553331242
MSH6 ; FBXO11
C 0.700 GeneticVariation CLINVAR Prospective evaluation of molecular screening for Lynch syndrome in patients with endometrial cancer ≤ 70 years. 22306203

2012
dbSNP: rs1553331242
rs1553331242
MSH6 ; FBXO11
C 0.700 GeneticVariation CLINVAR Germline MSH6 mutations are more prevalent in endometrial cancer patient cohorts than hereditary non polyposis colorectal cancer cohorts. 18269114

2008
dbSNP: rs1553332768
rs1553332768
MSH6 ; FBXO11
AG 0.700 GeneticVariation CLINVAR Application of a 5-tiered scheme for standardized classification of 2,360 unique mismatch repair gene variants in the InSiGHT locus-specific database. 24362816

2014
dbSNP: rs1553332768
rs1553332768
MSH6 ; FBXO11
AG 0.700 GeneticVariation CLINVAR Germline MSH6 mutations are more prevalent in endometrial cancer patient cohorts than hereditary non polyposis colorectal cancer cohorts. 18269114

2008
dbSNP: rs1553332776
rs1553332776
MSH6 ; FBXO11
C 0.700 GeneticVariation CLINVAR

dbSNP: rs1553333168
rs1553333168
MSH6 ; FBXO11
A 0.700 GeneticVariation CLINVAR

dbSNP: rs1553333175
rs1553333175
MSH6 ; FBXO11
A 0.700 GeneticVariation CLINVAR [Constitutional mismatch repair deficiency syndrome]. 26200421

2015
dbSNP: rs1553333175
rs1553333175
MSH6 ; FBXO11
A 0.700 GeneticVariation CLINVAR Germline MSH6 mutations are more prevalent in endometrial cancer patient cohorts than hereditary non polyposis colorectal cancer cohorts. 18269114

2008
dbSNP: rs1553333175
rs1553333175
MSH6 ; FBXO11
A 0.700 GeneticVariation CLINVAR Application of a 5-tiered scheme for standardized classification of 2,360 unique mismatch repair gene variants in the InSiGHT locus-specific database. 24362816

2014
dbSNP: rs1553333185
rs1553333185
MSH6 ; FBXO11
T 0.700 GeneticVariation CLINVAR

dbSNP: rs1553333753
rs1553333753
MSH6 ; FBXO11
ATTAT 0.700 GeneticVariation CLINVAR An Ashkenazi founder mutation in the MSH6 gene leading to HNPCC. 19851887

2010
dbSNP: rs1553333753
rs1553333753
MSH6 ; FBXO11
ATTAT 0.700 GeneticVariation CLINVAR Characterization of two Ashkenazi Jewish founder mutations in MSH6 gene causing Lynch syndrome. 21155762

2011
dbSNP: rs1558390582
rs1558390582
MSH6 ; FBXO11
T 0.700 GeneticVariation CLINVAR Application of a 5-tiered scheme for standardized classification of 2,360 unique mismatch repair gene variants in the InSiGHT locus-specific database. 24362816

2014
dbSNP: rs1558390582
rs1558390582
MSH6 ; FBXO11
T 0.700 GeneticVariation CLINVAR Germline MSH6 mutations are more prevalent in endometrial cancer patient cohorts than hereditary non polyposis colorectal cancer cohorts. 18269114

2008
dbSNP: rs267608098
rs267608098
MSH6 ; FBXO11
T 0.700 GeneticVariation CLINVAR Germline MSH6 mutations are more prevalent in endometrial cancer patient cohorts than hereditary non polyposis colorectal cancer cohorts. 18269114

2008
dbSNP: rs267608098
rs267608098
MSH6 ; FBXO11
T 0.700 GeneticVariation CLINVAR Application of a 5-tiered scheme for standardized classification of 2,360 unique mismatch repair gene variants in the InSiGHT locus-specific database. 24362816

2014