Gene: MSH6 ×
Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1064794075
rs1064794075
MSH6
AG 0.700 GeneticVariation CLINVAR Application of a 5-tiered scheme for standardized classification of 2,360 unique mismatch repair gene variants in the InSiGHT locus-specific database. 24362816

2014
dbSNP: rs1064794075
rs1064794075
MSH6
AG 0.700 GeneticVariation CLINVAR Germline MSH6 mutations are more prevalent in endometrial cancer patient cohorts than hereditary non polyposis colorectal cancer cohorts. 18269114

2008
dbSNP: rs1553408136
rs1553408136
MSH6
TG 0.700 CausalMutation CLINVAR

dbSNP: rs1553408158
rs1553408158
MSH6
A 0.700 CausalMutation CLINVAR

dbSNP: rs1553408306
rs1553408306
MSH6
G 0.700 CausalMutation CLINVAR

dbSNP: rs1553408388
rs1553408388
MSH6
T 0.700 CausalMutation CLINVAR Screening for Lynch syndrome (hereditary nonpolyposis colorectal cancer) among endometrial cancer patients. 16885385

2006
dbSNP: rs1553408388
rs1553408388
MSH6
T 0.700 CausalMutation CLINVAR Risks of Lynch syndrome cancers for MSH6 mutation carriers. 20028993

2010
dbSNP: rs1553408388
rs1553408388
MSH6
T 0.700 CausalMutation CLINVAR Identification of a Variety of Mutations in Cancer Predisposition Genes in Patients With Suspected Lynch Syndrome. 25980754

2015
dbSNP: rs1553408388
rs1553408388
MSH6
T 0.700 CausalMutation CLINVAR Comment on: Screening for Lynch Syndrome (Hereditary Nonpolyposis Colorectal Cancer) among Endometrial Cancer Patients. 17909073

2007
dbSNP: rs1558644683
rs1558644683
MSH6
CT 0.700 CausalMutation CLINVAR

dbSNP: rs1558644886
rs1558644886
MSH6
T 0.700 CausalMutation CLINVAR

dbSNP: rs1558645195
rs1558645195
MSH6
G 0.700 CausalMutation CLINVAR

dbSNP: rs786201042
rs786201042
MSH6
T 0.700 CausalMutation CLINVAR Characterization of a novel founder MSH6 mutation causing Lynch syndrome in the French Canadian population. 25318681

2015
dbSNP: rs786201042
rs786201042
MSH6
T 0.700 CausalMutation CLINVAR Risks of Lynch syndrome cancers for MSH6 mutation carriers. 20028993

2010
dbSNP: rs876660095
rs876660095
MSH6
T 0.700 GeneticVariation CLINVAR LOVD v.2.0: the next generation in gene variant databases. 21520333

2011
dbSNP: rs1054003194
rs1054003194
MSH6 ; FBXO11
TG 0.700 CausalMutation CLINVAR

dbSNP: rs1057517551
rs1057517551
MSH6 ; FBXO11
AT 0.700 CausalMutation CLINVAR

dbSNP: rs1057517763
rs1057517763
MSH6 ; FBXO11
A 0.700 CausalMutation CLINVAR

dbSNP: rs1057517764
rs1057517764
MSH6 ; FBXO11
AT 0.700 CausalMutation CLINVAR Tumor mismatch repair immunohistochemistry and DNA MLH1 methylation testing of patients with endometrial cancer diagnosed at age younger than 60 years optimizes triage for population-level germline mismatch repair gene mutation testing. 24323032

2014
dbSNP: rs1057517764
rs1057517764
MSH6 ; FBXO11
AT 0.700 CausalMutation CLINVAR Lynch syndrome mutation spectrum in New South Wales, Australia, including 55 novel mutations. 27064304

2016
dbSNP: rs1060502875
rs1060502875
MSH6 ; FBXO11
C 0.700 CausalMutation CLINVAR

dbSNP: rs1060502876
rs1060502876
MSH6 ; FBXO11
A 0.700 CausalMutation CLINVAR The contribution of deleterious germline mutations in BRCA1, BRCA2 and the mismatch repair genes to ovarian cancer in the population. 24728189

2014
dbSNP: rs1060502881
rs1060502881
MSH6 ; FBXO11
G 0.700 CausalMutation CLINVAR

dbSNP: rs1060502882
rs1060502882
MSH6 ; FBXO11
G 0.700 CausalMutation CLINVAR

dbSNP: rs1060502886
rs1060502886
MSH6 ; FBXO11
C 0.700 CausalMutation CLINVAR Prognostic impact of mismatch repair genes germline defects in colorectal cancer patients: are all mutations equal? 26485756

2015