Gene: MSH6 ×
Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1054003194
rs1054003194
MSH6 ; FBXO11
TG 0.700 CausalMutation CLINVAR

dbSNP: rs1057517551
rs1057517551
MSH6 ; FBXO11
AT 0.700 CausalMutation CLINVAR

dbSNP: rs1057517763
rs1057517763
MSH6 ; FBXO11
A 0.700 CausalMutation CLINVAR

dbSNP: rs1057517764
rs1057517764
MSH6 ; FBXO11
AT 0.700 CausalMutation CLINVAR Tumor mismatch repair immunohistochemistry and DNA MLH1 methylation testing of patients with endometrial cancer diagnosed at age younger than 60 years optimizes triage for population-level germline mismatch repair gene mutation testing. 24323032

2014
dbSNP: rs1057517764
rs1057517764
MSH6 ; FBXO11
AT 0.700 CausalMutation CLINVAR Lynch syndrome mutation spectrum in New South Wales, Australia, including 55 novel mutations. 27064304

2016
dbSNP: rs1060502875
rs1060502875
MSH6 ; FBXO11
C 0.700 CausalMutation CLINVAR

dbSNP: rs1060502876
rs1060502876
MSH6 ; FBXO11
A 0.700 CausalMutation CLINVAR The contribution of deleterious germline mutations in BRCA1, BRCA2 and the mismatch repair genes to ovarian cancer in the population. 24728189

2014
dbSNP: rs1060502881
rs1060502881
MSH6 ; FBXO11
G 0.700 CausalMutation CLINVAR

dbSNP: rs1060502882
rs1060502882
MSH6 ; FBXO11
G 0.700 CausalMutation CLINVAR

dbSNP: rs1060502886
rs1060502886
MSH6 ; FBXO11
C 0.700 CausalMutation CLINVAR Prognostic impact of mismatch repair genes germline defects in colorectal cancer patients: are all mutations equal? 26485756

2015
dbSNP: rs1060502888
rs1060502888
MSH6 ; FBXO11
A 0.700 CausalMutation CLINVAR Lynch-like syndrome: characterization and comparison with EPCAM deletion carriers. 25110875

2015
dbSNP: rs1060502890
rs1060502890
MSH6 ; FBXO11
G 0.700 CausalMutation CLINVAR

dbSNP: rs1060502891
rs1060502891
MSH6 ; FBXO11
T 0.700 CausalMutation CLINVAR

dbSNP: rs1060502903
rs1060502903
MSH6 ; FBXO11
GAAGA 0.700 CausalMutation CLINVAR

dbSNP: rs1060502918
rs1060502918
MSH6 ; FBXO11
T 0.700 CausalMutation CLINVAR

dbSNP: rs1060502926
rs1060502926
MSH6 ; FBXO11
C 0.700 GeneticVariation CLINVAR Germline MSH6 mutations are more prevalent in endometrial cancer patient cohorts than hereditary non polyposis colorectal cancer cohorts. 18269114

2008
dbSNP: rs1060502926
rs1060502926
MSH6 ; FBXO11
C 0.700 GeneticVariation CLINVAR Application of a 5-tiered scheme for standardized classification of 2,360 unique mismatch repair gene variants in the InSiGHT locus-specific database. 24362816

2014
dbSNP: rs1060502926
rs1060502926
MSH6 ; FBXO11
A 0.700 CausalMutation CLINVAR Germline MSH6 mutations are more prevalent in endometrial cancer patient cohorts than hereditary non polyposis colorectal cancer cohorts. 18269114

2008
dbSNP: rs1060502926
rs1060502926
MSH6 ; FBXO11
A 0.700 CausalMutation CLINVAR Application of a 5-tiered scheme for standardized classification of 2,360 unique mismatch repair gene variants in the InSiGHT locus-specific database. 24362816

2014
dbSNP: rs1060502926
rs1060502926
MSH6 ; FBXO11
A 0.700 CausalMutation CLINVAR Multigene panel analysis identified germline mutations of DNA repair genes in breast and ovarian cancer. 26436112

2015
dbSNP: rs1060502932
rs1060502932
MSH6 ; FBXO11
A 0.700 CausalMutation CLINVAR

dbSNP: rs1060502937
rs1060502937
MSH6 ; FBXO11
T 0.700 CausalMutation CLINVAR

dbSNP: rs1060502940
rs1060502940
MSH6 ; FBXO11
C 0.700 CausalMutation CLINVAR

dbSNP: rs1060502941
rs1060502941
MSH6 ; FBXO11
G 0.700 CausalMutation CLINVAR

dbSNP: rs1060502946
rs1060502946
MSH6 ; FBXO11
TAA 0.700 CausalMutation CLINVAR