|
rs4961
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The Gly460Trp variant of alpha-adducin is not associated with hypertension in white Anglo-Australians.
|
10371374 |
1999 |
|
rs4961
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The Gly460Trp variant of the alpha-adducin gene has been associated with renal sodium retention and salt-sensitive hypertension.
|
18458162 |
2008 |
|
rs4961
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The Gly460Trp variant of the alpha-adducin gene has been associated with the salt-sensitive and diuretic responsive form of hypertension.
|
19145769 |
2009 |
|
rs4961
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The ACE I/D, alpha-adducin Gly460Trp and aldosterone synthase -344C/T polymorphisms interact to influence systolic blood pressure in Chinese, suggesting that these genes might indeed predispose to hypertension, especially in an ecogenetic context characterized by a high salt intake.
|
15097233 |
2004 |
|
rs4961
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The ADD1 Gly460Trp polymorphism is significantly associated with an increased risk of coronary artery disease as well as blood pressure, indicating that ADD1 plays a role in the pathogenesis of coronary artery disease as well as hypertension.
|
17984662 |
2007 |
|
rs4961
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The ADD1 G460W-dominant model for the G allele was significantly associated with hypertension of IgAN patients (P = 0.001, Pc = 0.031 and OR = 1.37).
|
24271554 |
2014 |
|
rs4961
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The alpha-adducin (ADD1) Gly460Trp polymorphism has been associated with hypertension and response to diuretic therapy, but controversy exists.
|
18657677 |
2008 |
|
rs4961
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The alpha-adducin Gly460Trp polymorphism and the antihypertensive effects of exercise among men with high blood pressure.
|
17472579 |
2007 |
|
rs4961
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The angiotensin-converting enzyme (ACE) insertion/deletion (I/D) polymorphism and the Adducin-1 (ADD1) G460W nonsense single nucleotide polymorphism (SNP) have previously been associated to hypertension, whereas their association with preeclampsia (PE) and gestational hypertension (GH) is still controversial.
|
19443911 |
2009 |
|
rs4961
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The present study suggests that Gly460Trp polymorphism of the a-adducin gene may be involved in hypertension, particularly the low-renin type, in Japanese individuals.
|
9582105 |
1998 |
|
rs4961
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The results rather suggest that another variant in linkage disequilibrium with the Gly460Trp polymorphism increases susceptibility for hypertension.
|
10673730 |
2000 |
|
rs4961
|
|
|
0.100 |
GeneticVariation |
BEFREE |
These findings suggest that the Gly460Trp polymorphism of ADD-1 is not associated with hypertension.
|
15608390 |
2004 |
|
rs4961
|
|
|
0.100 |
GeneticVariation |
BEFREE |
These findings suggest the possibility that the Gly460Trp polymorphism of ADD-1 is associated with low renin hypertension.
|
12195119 |
2002 |
|
rs4961
|
|
|
0.100 |
GeneticVariation |
BEFREE |
This study examined the SNPs AGT rs699 (Met235Thr), ADD1 rs4961 (Gly460Trp), NPPA rs5063 (Val32Met), GPX1 rs1050450 (Pro198Leu), and AGTR1 rs5186 (A1166C) in relation to hypertension and salt sensitivity.
|
27480094 |
2017 |
|
rs4961
|
|
|
0.100 |
GeneticVariation |
BEFREE |
This study focused on 3 genetic polymorphisms that have previously been implicated in hypertension: the alpha-adducin (ADD1/Gly460Trp), beta1-adrenoreceptor (ADRB1/Arg389Gly), and G-protein beta3 subunit (GNB3/C825T) gene polymorphisms.
|
15055253 |
2004 |
|
rs372777117
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Two point mutations in MHS alpha- (F316Y) and beta- (Q529R) adducin genes have been shown to be associated with hypertension in genetic crosses of MHS and MNS rats.
|
9678591 |
1998 |
|
rs1255327081
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Two point mutations in MHS alpha- (F316Y) and beta- (Q529R) adducin genes have been shown to be associated with hypertension in genetic crosses of MHS and MNS rats.
|
9678591 |
1998 |
|
rs4961
|
|
|
0.100 |
GeneticVariation |
BEFREE |
We recently found that femoral intima media thickness, as well as the incidence of hypertension, is influenced by genes encoding the angiotensin-converting enzyme (ACE; insertion/deletion [I/D]) polymorphism, alpha-adducin (Gly460Trp), and aldosterone synthase (-344C/T).
|
11728946 |
2001 |