LEP, leptin, 3952

N. diseases: 114; N. variants: 3
Source: CURATED ×
Disease Type Disease Class Semantic Type N. genes d N. SNPs d Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
CUI: C0028754
Disease: Obesity
Obesity 		disease Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases Disease or Syndrome 205 266 0.700 None 0.952 14 1973 2020
CUI: C0043094
Disease: Weight Gain
Weight Gain 		phenotype Pathological Conditions, Signs and Symptoms Finding 102 12 0.300 None 1.000 8 2004 2018
CUI: C0015695
Disease: Fatty Liver
Fatty Liver 		disease Digestive System Diseases Disease or Syndrome 88 0.600 None 1.000 6 2003 2020
CUI: C0038358
Disease: Gastric ulcer
Gastric ulcer 		disease Digestive System Diseases Disease or Syndrome 18 0.300 None 1.000 6 1999 2008
CUI: C2711227
Disease: Steatohepatitis
Steatohepatitis 		disease Digestive System Diseases Disease or Syndrome 88 9 0.400 None 1.000 6 2000 2020
CUI: C0011581
Disease: Depressive disorder
Depressive disorder 		disease Mental Disorders Mental or Behavioral Dysfunction 289 7 0.400 None 1.000 5 2007 2019
CUI: C0011570
Disease: Mental Depression
Mental Depression 		disease Behavior and Behavior Mechanisms Mental or Behavioral Dysfunction 254 0.400 None 1.000 5 2007 2019
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		group Cardiovascular Diseases Disease or Syndrome 190 233 0.600 None 0.972 4 1998 2020
CUI: C0236663
Disease: Alcohol withdrawal syndrome
Alcohol withdrawal syndrome 		disease Chemically-Induced Disorders; Mental Disorders Disease or Syndrome 8 1 0.330 None 1.000 3 2004 2019
CUI: C0021655
Disease: Insulin Resistance
Insulin Resistance 		phenotype Nutritional and Metabolic Diseases Pathologic Function 60 53 0.500 None 1.000 3 2000 2014
CUI: C0023893
Disease: Liver Cirrhosis, Experimental
Liver Cirrhosis, Experimental 		disease Pathological Conditions, Signs and Symptoms; Digestive System Diseases Experimental Model of Disease 774 0.500 None 1.000 3 2003 2018
CUI: C0920563
Disease: Insulin Sensitivity
Insulin Sensitivity 		phenotype Nutritional and Metabolic Diseases Pathologic Function 60 0.300 None 1.000 3 2000 2014
CUI: C0271650
Disease: Impaired glucose tolerance
Impaired glucose tolerance 		phenotype Nutritional and Metabolic Diseases Disease or Syndrome 25 1 0.600 None 0.944 2 1996 2020
CUI: C0021368
Disease: Inflammation
Inflammation 		phenotype Pathological Conditions, Signs and Symptoms Pathologic Function 127 0.370 None 1.000 2 2003 2017
CUI: C0036341
Disease: Schizophrenia
Schizophrenia 		disease Mental Disorders Mental or Behavioral Dysfunction 883 1629 0.400 None 1.000 2 2005 2019
CUI: C0020619
Disease: Hypogonadism
Hypogonadism 		disease Endocrine System Diseases Disease or Syndrome 16 6 0.650 None 1.000 2 1998 2017
CUI: C0033975
Disease: Psychotic Disorders
Psychotic Disorders 		group Mental Disorders Mental or Behavioral Dysfunction 101 68 0.350 None 1.000 2 2005 2019
CUI: C0271623
Disease: Hypogonadotropic hypogonadism
Hypogonadotropic hypogonadism 		disease Endocrine System Diseases Disease or Syndrome 15 1 0.350 None 1.000 2 1998 2019
CUI: C0020505
Disease: Hyperphagia
Hyperphagia 		phenotype Pathological Conditions, Signs and Symptoms Finding 4 3 0.400 None 1.000 2 2014 2015
CUI: C0556385
Disease: Craving for alcohol
Craving for alcohol 		phenotype Finding 3 0.300 None 1.000 2 2010 2015
CUI: C0020456
Disease: Hyperglycemia
Hyperglycemia 		disease Nutritional and Metabolic Diseases Disease or Syndrome 30 30 0.400 None 1.000 2 2009 2019
CUI: C0948896
Disease: Primary hypogonadism
Primary hypogonadism 		disease Endocrine System Diseases Disease or Syndrome 15 5 0.400 None 1.000 2 1998 2004
CUI: C1855520
Disease: Hyperglycemia, Postprandial
Hyperglycemia, Postprandial 		phenotype Nutritional and Metabolic Diseases Finding 30 0.300 None 1.000 2 2009 2011
CUI: C3489396
Disease: Hypogonadism, Isolated Hypogonadotropic
Hypogonadism, Isolated Hypogonadotropic 		disease Endocrine System Diseases Disease or Syndrome 15 1 0.300 None 1.000 2 1998 2004
CUI: C0028756
Disease: Obesity, Morbid
Obesity, Morbid 		disease Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases Disease or Syndrome 7 1 0.400 None 0.969 2 1997 2020