Orthostatic intolerance
|
0.610 |
Biomarker
|
phenotype |
CTD_human |
Here the hypothesis that abnormal norepinephrine transporter (NET) function might contribute to the pathophysiology in some patients with OI was tested.
|
11458707 |
2001 |
Orthostatic intolerance
|
0.610 |
GeneticVariation
|
phenotype |
UNIPROT |
In a patient with orthostatic intolerance and her relatives, we measured postural blood pressure, heart rate, plasma catecholamines, and systemic norepinephrine spillover and clearance, and we sequenced the norepinephrine-transporter gene and evaluated its function.
|
10684912 |
2000 |
Orthostatic intolerance
|
0.610 |
GermlineCausalMutation
|
phenotype |
ORPHANET |
In a patient with orthostatic intolerance and her relatives, we measured postural blood pressure, heart rate, plasma catecholamines, and systemic norepinephrine spillover and clearance, and we sequenced the norepinephrine-transporter gene and evaluated its function.
|
10684912 |
2000 |
Mental Depression
|
0.600 |
Biomarker
|
disease |
PSYGENET |
Our results suggest that a NET 182C and 5-HTTLPR polymorphism interaction is associated with susceptibility to treatment resistant depression and ECT treatment response in antidepressant resistant depression patients.
|
25650523 |
2015 |
Mental Depression
|
0.600 |
Biomarker
|
disease |
PSYGENET |
Genetic moderation of child maltreatment effects on depression and internalizing symptoms by serotonin transporter linked polymorphic region (5-HTTLPR), brain-derived neurotrophic factor (BDNF), norepinephrine transporter (NET), and corticotropin releasing hormone receptor 1 (CRHR1) genes in African American children.
|
25422957 |
2014 |
Mental Depression
|
0.600 |
Biomarker
|
disease |
PSYGENET |
Although several studies have investigated possible associations between norepinephrine neurotransmitter transporter gene (SLC6A2) polymorphisms and depression, few studies have examined associations between SLC6A2 polymorphisms and suicide.
|
24655776 |
2014 |
Mental Depression
|
0.600 |
Biomarker
|
disease |
PSYGENET |
Compared with VM rats, the PM rats showed significant relief of depression-like behaviors, decrease in the malondialdehyde level, increase in superoxide dismutase and catalase activities, and increase in 5-HTT and NET expression.
|
23636256 |
2013 |
Mental Depression
|
0.600 |
Biomarker
|
disease |
PSYGENET |
The results from our study do not suggest SLC6A2 as a susceptibility gene for depression in the Danish population.
|
23969988 |
2013 |
Depressive disorder
|
0.400 |
Biomarker
|
disease |
PSYGENET |
Our results suggest that a NET 182C and 5-HTTLPR polymorphism interaction is associated with susceptibility to treatment resistant depression and ECT treatment response in antidepressant resistant depression patients.
|
25650523 |
2015 |
Unipolar Depression
|
0.400 |
Biomarker
|
disease |
PSYGENET |
SLC6A2 variants may predict remission from major depression after venlafaxine treatment in Han Chinese population.
|
25512257 |
2015 |
Unipolar Depression
|
0.400 |
Biomarker
|
disease |
PSYGENET |
Serotonin transporter (5-HTTLPR) and norepinephrine transporter (NET) gene polymorphisms: susceptibility and treatment response of electroconvulsive therapy in treatment resistant depression.
|
25650523 |
2015 |
Unipolar Depression
|
0.400 |
Biomarker
|
disease |
PSYGENET |
This study attempted to examine the relationship between polymorphisms of NET gene and MD.
|
26061302 |
2015 |
Major Depressive Disorder
|
0.400 |
Biomarker
|
disease |
PSYGENET |
This study attempted to examine the relationship between polymorphisms of NET gene and MD.
|
26061302 |
2015 |
Major Depressive Disorder
|
0.400 |
Biomarker
|
disease |
PSYGENET |
Serotonin transporter (5-HTTLPR) and norepinephrine transporter (NET182C) polymorphisms are associated with susceptibility and treatment response in major depressive disorder (MDD).
|
25650523 |
2015 |
Major Depressive Disorder
|
0.400 |
Biomarker
|
disease |
PSYGENET |
The aim of this study was to examine whether polymorphisms in the norepinephrine transporter gene (SLC6A2) associate with remission after venlafaxine treatment for MDD.
|
25512257 |
2015 |
Depressive disorder
|
0.400 |
Biomarker
|
disease |
PSYGENET |
Although several studies have investigated possible associations between norepinephrine neurotransmitter transporter gene (SLC6A2) polymorphisms and depression, few studies have examined associations between SLC6A2 polymorphisms and suicide.
|
24655776 |
2014 |
Depressive disorder
|
0.400 |
Biomarker
|
disease |
PSYGENET |
Genetic moderation of child maltreatment effects on depression and internalizing symptoms by serotonin transporter linked polymorphic region (5-HTTLPR), brain-derived neurotrophic factor (BDNF), norepinephrine transporter (NET), and corticotropin releasing hormone receptor 1 (CRHR1) genes in African American children.
|
25422957 |
2014 |
Unipolar Depression
|
0.400 |
Biomarker
|
disease |
PSYGENET |
Association between norepinephrine transporter gene (SLC6A2) polymorphisms and suicide in patients with major depressive disorder.
|
24655776 |
2014 |
Major Depressive Disorder
|
0.400 |
Biomarker
|
disease |
PSYGENET |
There were no relationships between lethality scores and SLC6A2 polymorphisms in suicidal MDD.
|
24655776 |
2014 |
Depressive disorder
|
0.400 |
Biomarker
|
disease |
PSYGENET |
The results from our study do not suggest SLC6A2 as a susceptibility gene for depression in the Danish population.
|
23969988 |
2013 |
Depressive disorder
|
0.400 |
Biomarker
|
disease |
PSYGENET |
Compared with VM rats, the PM rats showed significant relief of depression-like behaviors, decrease in the malondialdehyde level, increase in superoxide dismutase and catalase activities, and increase in 5-HTT and NET expression.
|
23636256 |
2013 |
Unipolar Depression
|
0.400 |
Biomarker
|
disease |
PSYGENET |
Methylation of the SLC6a2 gene promoter in major depression and panic disorder.
|
24312678 |
2013 |
Major Depressive Disorder
|
0.400 |
Biomarker
|
disease |
PSYGENET |
Patients with MDD or panic disorder were not found to differ significantly from healthy controls in the pattern of methylation of the SLC6a2 gene promotor.
|
24312678 |
2013 |
Hypertensive disease
|
0.360 |
Biomarker
|
group |
CTD_human |
Effect of the rs168924 single-nucleotide polymorphism in the SLC6A2 catecholamine transporter gene on blood pressure in Caucasians.
|
22533655 |
2012 |
Schizophrenia
|
0.350 |
Biomarker
|
disease |
PSYGENET |
Dysregulation of the norepinephrine transporter sustains cortical hypodopaminergia and schizophrenia-like behaviors in neuronal rictor null mice.
|
20543991 |
2010 |