SNCA, synuclein alpha, 6622

N. diseases: 36; N. variants: 44
Source: CURATED ×
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs10005233
rs10005233
Entrez Id: 6622
Gene Symbol: SNCA
SNCA
CUI: C0003467
Disease:
Anxiety 		C 0.700 GeneticVariation GWASCAT Meta-analysis of genome-wide association studies for neuroticism in 449,484 individuals identifies novel genetic loci and pathways. 29942085 2018
dbSNP: rs1372518
rs1372518
Entrez Id: 6622;644248
Gene Symbol: SNCA;SNCA-AS1
SNCA;SNCA-AS1
CUI: C2985280
Disease:
Blood Protein Measurement 		C 0.700 GeneticVariation GWASCAT Co-regulatory networks of human serum proteins link genetics to disease. 30072576 2018
dbSNP: rs2245801
rs2245801
Entrez Id: 6622;644248
Gene Symbol: SNCA;SNCA-AS1
SNCA;SNCA-AS1
CUI: C2985280
Disease:
Blood Protein Measurement 		C 0.700 GeneticVariation GWASCAT Genomic atlas of the human plasma proteome. 29875488 2018
dbSNP: rs2737002
rs2737002
Entrez Id: 6622
Gene Symbol: SNCA
SNCA
CUI: C2985280
Disease:
Blood Protein Measurement 		G 0.700 GeneticVariation GWASCAT Co-regulatory networks of human serum proteins link genetics to disease. 30072576 2018
dbSNP: rs104893875
rs104893875
Entrez Id: 6622
Gene Symbol: SNCA
SNCA
CUI: C0752347
Disease:
Lewy Body Disease 		0.860 GeneticVariation UNIPROT The new mutation, E46K, of alpha-synuclein causes Parkinson and Lewy body dementia. 14755719 2004
dbSNP: rs104893875
rs104893875
Entrez Id: 6622
Gene Symbol: SNCA
SNCA
CUI: C0752347
Disease:
Lewy Body Disease 		T 0.860 CausalMutation CLINVAR
dbSNP: rs104893877
rs104893877
Entrez Id: 6622
Gene Symbol: SNCA
SNCA
CUI: C0752347
Disease:
Lewy Body Disease 		T 0.760 CausalMutation CLINVAR
dbSNP: rs7681440
rs7681440
Entrez Id: 6622;644248
Gene Symbol: SNCA;SNCA-AS1
SNCA;SNCA-AS1
CUI: C0752347
Disease:
Lewy Body Disease 		0.700 GeneticVariation GWASCAT Investigating the genetic architecture of dementia with Lewy bodies: a two-stage genome-wide association study. 29263008 2018
dbSNP: rs11931074
rs11931074
Entrez Id: 6622;105377329
Gene Symbol: SNCA;LOC105377329
SNCA;LOC105377329
CUI: C0030567
Disease:
Parkinson Disease 		0.900 GeneticVariation GWASDB Web-based genome-wide association study identifies two novel loci and a substantial genetic component for Parkinson's disease. 21738487 2011
dbSNP: rs11931074
rs11931074
Entrez Id: 6622;105377329
Gene Symbol: SNCA;LOC105377329
SNCA;LOC105377329
CUI: C0030567
Disease:
Parkinson Disease 		0.900 GeneticVariation GWASCAT Genome-wide association study identifies common variants at four loci as genetic risk factors for Parkinson's disease. 19915576 2009
dbSNP: rs11931074
rs11931074
Entrez Id: 6622;105377329
Gene Symbol: SNCA;LOC105377329
SNCA;LOC105377329
CUI: C0030567
Disease:
Parkinson Disease 		0.900 GeneticVariation GWASDB Genome-wide association study reveals genetic risk underlying Parkinson's disease. 19915575 2009
dbSNP: rs11931074
rs11931074
Entrez Id: 6622;105377329
Gene Symbol: SNCA;LOC105377329
SNCA;LOC105377329
CUI: C0030567
Disease:
Parkinson Disease 		0.900 GeneticVariation GWASDB Comprehensive research synopsis and systematic meta-analyses in Parkinson's disease genetics: The PDGene database. 22438815 2012
dbSNP: rs11931074
rs11931074
Entrez Id: 6622;105377329
Gene Symbol: SNCA;LOC105377329
SNCA;LOC105377329
CUI: C0030567
Disease:
Parkinson Disease 		G 0.900 GeneticVariation GWASDB Genome-wide association study identifies common variants at four loci as genetic risk factors for Parkinson's disease. 19915576 2009
dbSNP: rs356219
rs356219
Entrez Id: 6622;105377329
Gene Symbol: SNCA;LOC105377329
SNCA;LOC105377329
CUI: C0030567
Disease:
Parkinson Disease 		0.900 GeneticVariation GWASDB Comprehensive research synopsis and systematic meta-analyses in Parkinson's disease genetics: The PDGene database. 22438815 2012
dbSNP: rs356219
rs356219
Entrez Id: 6622;105377329
Gene Symbol: SNCA;LOC105377329
SNCA;LOC105377329
CUI: C0030567
Disease:
Parkinson Disease 		0.900 GeneticVariation GWASDB Web-based genome-wide association study identifies two novel loci and a substantial genetic component for Parkinson's disease. 21738487 2011
dbSNP: rs356219
rs356219
Entrez Id: 6622;105377329
Gene Symbol: SNCA;LOC105377329
SNCA;LOC105377329
CUI: C0030567
Disease:
Parkinson Disease 		0.900 GeneticVariation GWASDB Identification of a novel Parkinson's disease locus via stratified genome-wide association study. 24511991 2014
dbSNP: rs356219
rs356219
Entrez Id: 6622;105377329
Gene Symbol: SNCA;LOC105377329
SNCA;LOC105377329
CUI: C0030567
Disease:
Parkinson Disease 		0.900 GeneticVariation GWASCAT Comprehensive research synopsis and systematic meta-analyses in Parkinson's disease genetics: The PDGene database. 22438815 2012
dbSNP: rs356219
rs356219
Entrez Id: 6622;105377329
Gene Symbol: SNCA;LOC105377329
SNCA;LOC105377329
CUI: C0030567
Disease:
Parkinson Disease 		G 0.900 GeneticVariation GWASCAT Imputation of sequence variants for identification of genetic risks for Parkinson's disease: a meta-analysis of genome-wide association studies. 21292315 2011
dbSNP: rs356219
rs356219
Entrez Id: 6622;105377329
Gene Symbol: SNCA;LOC105377329
SNCA;LOC105377329
CUI: C0030567
Disease:
Parkinson Disease 		G 0.900 GeneticVariation GWASDB Imputation of sequence variants for identification of genetic risks for Parkinson's disease: a meta-analysis of genome-wide association studies. 21292315 2011
dbSNP: rs2736990
rs2736990
Entrez Id: 6622
Gene Symbol: SNCA
SNCA
CUI: C0030567
Disease:
Parkinson Disease 		C 0.860 GeneticVariation GWASCAT Genome-wide association study reveals genetic risk underlying Parkinson's disease. 19915575 2009
dbSNP: rs2736990
rs2736990
Entrez Id: 6622
Gene Symbol: SNCA
SNCA
CUI: C0030567
Disease:
Parkinson Disease 		0.860 GeneticVariation GWASDB Comprehensive research synopsis and systematic meta-analyses in Parkinson's disease genetics: The PDGene database. 22438815 2012
dbSNP: rs2736990
rs2736990
Entrez Id: 6622
Gene Symbol: SNCA
SNCA
CUI: C0030567
Disease:
Parkinson Disease 		0.860 GeneticVariation GWASDB Identification of a novel Parkinson's disease locus via stratified genome-wide association study. 24511991 2014
dbSNP: rs2736990
rs2736990
Entrez Id: 6622
Gene Symbol: SNCA
SNCA
CUI: C0030567
Disease:
Parkinson Disease 		0.860 GeneticVariation GWASDB Web-based genome-wide association study identifies two novel loci and a substantial genetic component for Parkinson's disease. 21738487 2011
dbSNP: rs2736990
rs2736990
Entrez Id: 6622
Gene Symbol: SNCA
SNCA
CUI: C0030567
Disease:
Parkinson Disease 		C 0.860 GeneticVariation GWASDB Genome-wide association study reveals genetic risk underlying Parkinson's disease. 19915575 2009
dbSNP: rs2736990
rs2736990
Entrez Id: 6622
Gene Symbol: SNCA
SNCA
CUI: C0030567
Disease:
Parkinson Disease 		0.860 GeneticVariation GWASDB Genome-wide association study confirms SNPs in SNCA and the MAPT region as common risk factors for Parkinson disease. 20070850 2010