TFPI, tissue factor pathway inhibitor, 7035

N. diseases: 230; N. variants: 6
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs4140885
rs4140885
Entrez Id: 7035;105373786
Gene Symbol: TFPI;LOC105373786
TFPI;LOC105373786
CUI: C0018810
Disease:
heart rate 		A 0.800 GeneticVariation GWASDB Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders. 23583979 2013
dbSNP: rs4140885
rs4140885
Entrez Id: 7035;105373786
Gene Symbol: TFPI;LOC105373786
TFPI;LOC105373786
CUI: C0018810
Disease:
heart rate 		A 0.800 GeneticVariation GWASCAT Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders. 23583979 2013
dbSNP: rs8176433
rs8176433
Entrez Id: 7035;105373786
Gene Symbol: TFPI;LOC105373786
TFPI;LOC105373786
CUI: C0428474
Disease:
Serum LDL cholesterol measurement 		0.700 GeneticVariation GWASDB Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci. 23063622 2012
dbSNP: rs8176433
rs8176433
Entrez Id: 7035;105373786
Gene Symbol: TFPI;LOC105373786
TFPI;LOC105373786
CUI: C0202117
Disease:
Low density lipoprotein cholesterol measurement 		0.700 GeneticVariation GWASDB Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci. 23063622 2012
dbSNP: rs8176433
rs8176433
Entrez Id: 7035;105373786
Gene Symbol: TFPI;LOC105373786
TFPI;LOC105373786
CUI: C1445957
Disease:
Serum total cholesterol measurement 		0.700 GeneticVariation GWASDB Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci. 23063622 2012
dbSNP: rs8176445
rs8176445
Entrez Id: 7035;105373786
Gene Symbol: TFPI;LOC105373786
TFPI;LOC105373786
CUI: C0428474
Disease:
Serum LDL cholesterol measurement 		0.700 GeneticVariation GWASDB Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci. 23063622 2012
dbSNP: rs8176445
rs8176445
Entrez Id: 7035;105373786
Gene Symbol: TFPI;LOC105373786
TFPI;LOC105373786
CUI: C1445957
Disease:
Serum total cholesterol measurement 		0.700 GeneticVariation GWASDB Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci. 23063622 2012
dbSNP: rs8176445
rs8176445
Entrez Id: 7035;105373786
Gene Symbol: TFPI;LOC105373786
TFPI;LOC105373786
CUI: C0202117
Disease:
Low density lipoprotein cholesterol measurement 		0.700 GeneticVariation GWASDB Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci. 23063622 2012
dbSNP: rs8176445
rs8176445
Entrez Id: 7035;105373786
Gene Symbol: TFPI;LOC105373786
TFPI;LOC105373786
CUI: C0202236
Disease:
Triglycerides measurement 		0.700 GeneticVariation GWASDB Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci. 23063622 2012
dbSNP: rs6434222
rs6434222
Entrez Id: 7035;105373786
Gene Symbol: TFPI;LOC105373786
TFPI;LOC105373786
CUI: C1956346
Disease:
Coronary Artery Disease 		0.010 GeneticVariation BEFREE Meanwhile, two SNPs of TFPI (rs7586970 and rs6434222) were found to be associated with CAD in both groups. 28716011 2017
dbSNP: rs7586970
rs7586970
Entrez Id: 7035;105373786
Gene Symbol: TFPI;LOC105373786
TFPI;LOC105373786
CUI: C1956346
Disease:
Coronary Artery Disease 		0.010 GeneticVariation BEFREE Meanwhile, two SNPs of TFPI (rs7586970 and rs6434222) were found to be associated with CAD in both groups. 28716011 2017
dbSNP: rs7586970
rs7586970
Entrez Id: 7035;105373786
Gene Symbol: TFPI;LOC105373786
TFPI;LOC105373786
CUI: C0149871
Disease:
Deep Vein Thrombosis 		0.010 GeneticVariation BEFREE Thus, the Asn2</span>21Ser mutation occurring in the TFPI-beta form was associated with the total TFPI level, but not a risk for DVT. 20523161 2009
dbSNP: rs5940
rs5940
Entrez Id: 7035;105373786
Gene Symbol: TFPI;LOC105373786
TFPI;LOC105373786
CUI: C0149871
Disease:
Deep Vein Thrombosis 		0.010 GeneticVariation BEFREE Analysis of Val264Met in 317 patients with deep vein thrombosis (DVT) and 292 controls showed no association between Val264Met and DVT. 11380428 2001
dbSNP: rs5940
rs5940
Entrez Id: 7035;105373786
Gene Symbol: TFPI;LOC105373786
TFPI;LOC105373786
CUI: C0948089
Disease:
Acute Coronary Syndrome 		0.010 GeneticVariation BEFREE The V264M polymorphism was found in 9.2% of the cases and 4.9% of the controls; the associated odds ratio (OR) for acute coronary syndromes was 2.0 (95% confidence interval [CI], 0.7 to 5.1). 10195910 1999
dbSNP: rs5940
rs5940
Entrez Id: 7035;105373786
Gene Symbol: TFPI;LOC105373786
TFPI;LOC105373786
CUI: C0027051
Disease:
Myocardial Infarction 		0.010 GeneticVariation BEFREE The possible link between the V264M polymorphism and coronary heart disease was checked in a large case-control study of myocardial infarction (Etude Cas-Témoins de l'Infarctus du Myocarde [the ECTIM Study]). 10195910 1999