Source: LHGDN

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
ND1 P03886 NADH dehydrogenase, subunit 1 (complex I) Enzyme 0.522 0.769 13
TRNI tRNA 0.743 0.385 4
ND2 P03891 MTND2 0.601 0.615 3
LPA P08519 lipoprotein(a) Enzyme 6.6E-89 0.444 0.769 13
ROS1 P08922 ROS proto-oncogene 1, receptor tyrosine kinase Kinase 1.6E-72 0.439 0.885 2
CD36 P16671 CD36 molecule Receptor 1.1E-60 0.446 0.846 24
ACE P12821 angiotensin I converting enzyme Enzyme 1.0E-37 0.328 0.923 94
CORIN Q9Y5Q5 corin, serine peptidase 6.5E-35 0.695 0.538 2
SLC12A3 P55017 solute carrier family 12 member 3 Transporter 3.0E-32 0.493 0.808 4
SELP P16109 selectin P 5.0E-32 0.460 0.769 25
ENPEP Q07075 glutamyl aminopeptidase Enzyme 1.4E-28 0.564 0.731 1
ERAP1 Q9NZ08 endoplasmic reticulum aminopeptidase 1 Enzyme 2.1E-26 0.556 0.692 2
WNK4 Q96J92 WNK lysine deficient protein kinase 4 Kinase 6.9E-25 0.644 0.538 3
CYP4A11 Q02928 cytochrome P450 family 4 subfamily A member 11 Enzyme 1.1E-24 0.695 0.462 2
SLC6A19 Q695T7 solute carrier family 6 member 19 1.8E-24 0.695 0.577 1
CLCNKB P51801 chloride voltage-gated channel Kb Ion channel 1.4E-22 0.593 0.692 2
XDH P47989 xanthine dehydrogenase Enzyme 2.6E-22 0.529 0.846 11
EPHX2 P34913 epoxide hydrolase 2 Enzyme 1.8E-21 0.568 0.654 4
NOX4 Q9NPH5 NADPH oxidase 4 Enzyme 5.8E-20 0.471 0.885 7
CYP11B2 P19099 cytochrome P450 family 11 subfamily B member 2 7.1E-19 0.553 0.615 9
MMP9 P14780 matrix metallopeptidase 9 Enzyme 1.9E-17 0.305 0.923 149
CLCNKA P51800 chloride voltage-gated channel Ka Ion channel 4.2E-17 0.711 0.385 2
CYP3A5 P20815 cytochrome P450 family 3 subfamily A member 5 Enzyme 6.3E-17 0.511 0.846 5
CYP4F2 P78329 cytochrome P450 family 4 subfamily F member 2 Enzyme 7.6E-17 0.674 0.308 4