Source: LHGDN

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
IL6 P05231 interleukin 6 0.32 0.248 0.962 177
IL10 P22301 interleukin 10 5.9E-03 0.281 0.923 134
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962 112
MTHFR P42898 methylenetetrahydrofolate reductase 3.2E-10 0.337 0.885 110
CRP P02741 C-reactive protein 3.7E-03 0.299 0.962 85
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885 84
LEP P41159 leptin 0.46 0.349 0.846 78
NOS3 P29474 nitric oxide synthase 3 6.7E-07 0.378 0.885 77
NOS2 P35228 nitric oxide synthase 2 4.0E-15 0.364 0.923 67
ADIPOQ Q15848 adiponectin, C1Q and collagen domain containing 4.6E-09 0.376 0.885 67
GSTM1 P09488 glutathione S-transferase mu 1 2.1E-03 0.380 0.923 62
GSTT1 P30711 glutathione S-transferase theta 1 1.5E-04 0.393 0.923 55
IL1RN P18510 interleukin 1 receptor antagonist 3.1E-02 0.373 0.923 55
HMOX1 P09601 heme oxygenase 1 9.7E-03 0.381 0.923 53
PON1 P27169 paraoxonase 1 9.8E-11 0.409 0.885 52
TNFRSF11B O00300 TNF receptor superfamily member 11b 0.16 0.422 0.808 50
SELE P16581 selectin E 7.9E-10 0.447 0.808 49
GHRL Q9UBU3 ghrelin and obestatin prepropeptide 1.4E-11 0.517 0.769 43
NPPB P16860 natriuretic peptide B 9.9E-06 0.513 0.808 42
APOA1 P02647 apolipoprotein A1 5.5E-04 0.429 0.885 31
ENG P17813 endoglin 1.00 0.446 0.846 28
CLU P10909 clusterin 7.8E-05 0.426 0.885 26
IL15 P40933 interleukin 15 0.71 0.422 0.846 26
INS P01308 insulin 0.30 0.445 0.923 25