Source: GENOMICS_ENGLAND

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
TKFC Q3LXA3 triokinase and FMN cyclase 3.2E-12 0.839 0.192 4
TAOK1 Q7L7X3 TAO kinase 1 Kinase 1.00 0.792 0.269 4
GABRA2 P47869 gamma-aminobutyric acid type A receptor subunit alpha2 Ion channel 1.00 0.641 0.346 3
ACTL6A O96019 actin like 6A Cellular structure 1.00 0.678 0.346 3
AP4S1 Q9Y587 adaptor related protein complex 4 subunit sigma 1 Transporter 1.7E-06 0.674 0.385 4
STT3B Q8TCJ2 STT3 oligosaccharyltransferase complex catalytic subunit B Enzyme 1.00 0.760 0.385 4
TRAPPC12 Q8WVT3 trafficking protein particle complex 12 Enzyme 5.4E-16 0.751 0.385 3
GABRA5 P31644 gamma-aminobutyric acid type A receptor subunit alpha5 Ion channel 0.91 0.621 0.385 2
ALKBH8 Q96BT7 alkB homolog 8, tRNA methyltransferase 2.0E-04 0.716 0.423 4
SZT2 Q5T011 SZT2 subunit of KICSTOR complex 2.3E-14 0.670 0.423 3
TCF20 Q9UGU0 transcription factor 20 Transcription factor 1.00 0.644 0.423 3
PNPT1 Q8TCS8 polyribonucleotide nucleotidyltransferase 1 Enzyme 4.0E-04 0.653 0.462 7
PIBF1 Q8WXW3 progesterone immunomodulatory binding factor 1 1.9E-11 0.670 0.462 6
ZNF335 Q9H4Z2 zinc finger protein 335 Transcription factor 6.9E-07 0.711 0.462 4
UBTF P17480 upstream binding transcription factor 1.00 0.705 0.462 4
TBC1D20 Q96BZ9 TBC1 domain family member 20 0.93 0.621 0.500 5
GLRA1 P23415 glycine receptor alpha 1 Ion channel 1.6E-04 0.628 0.500 4
KDM5C P41229 lysine demethylase 5C 1.00 0.581 0.538 7
ABAT P80404 4-aminobutyrate aminotransferase Enzyme 6.3E-03 0.628 0.538 3
SLC5A6 Q9Y289 solute carrier family 5 member 6 Transporter 6.1E-03 0.674 0.577 18
PIGQ Q9BRB3 phosphatidylinositol glycan anchor biosynthesis class Q Enzyme 1.4E-06 0.610 0.577 6
STT3A P46977 STT3 oligosaccharyltransferase complex catalytic subunit A Enzyme 2.0E-03 0.670 0.577 4
CACNA2D2 Q9NY47 calcium voltage-gated channel auxiliary subunit alpha2delta 2 Ion channel 1.00 0.626 0.615 6
DIAPH1 O60610 diaphanous related formin 1 0.92 0.623 0.654 6