Source: GENOMICS_ENGLAND

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
GABRA5 P31644 gamma-aminobutyric acid type A receptor subunit alpha5 Ion channel 0.91 0.621 0.385 2
ABAT P80404 4-aminobutyrate aminotransferase Enzyme 6.3E-03 0.628 0.538 3
ACTL6A O96019 actin like 6A Cellular structure 1.00 0.678 0.346 3
DEGS1 O15121 delta 4-desaturase, sphingolipid 1 0.14 0.621 0.731 3
GABRA2 P47869 gamma-aminobutyric acid type A receptor subunit alpha2 Ion channel 1.00 0.641 0.346 3
IGF1R P08069 insulin like growth factor 1 receptor Kinase 0.97 0.399 0.885 3
KDM1A O60341 lysine demethylase 1A Epigenetic regulator 1.00 0.512 0.808 3
RAC1 P63000 Rac family small GTPase 1 Enzyme modulator 0.76 0.429 0.962 3
SZT2 Q5T011 SZT2 subunit of KICSTOR complex 2.3E-14 0.670 0.423 3
TCF20 Q9UGU0 transcription factor 20 Transcription factor 1.00 0.644 0.423 3
TRAPPC12 Q8WVT3 trafficking protein particle complex 12 Enzyme 5.4E-16 0.751 0.385 3
TRIT1 Q9H3H1 tRNA isopentenyltransferase 1 Enzyme 4.1E-11 0.621 0.692 3
ALKBH8 Q96BT7 alkB homolog 8, tRNA methyltransferase 2.0E-04 0.716 0.423 4
AP4S1 Q9Y587 adaptor related protein complex 4 subunit sigma 1 Transporter 1.7E-06 0.674 0.385 4
GLRA1 P23415 glycine receptor alpha 1 Ion channel 1.6E-04 0.628 0.500 4
SPART Q8N0X7 spartin 3.0E-07 0.588 0.654 4
STT3A P46977 STT3 oligosaccharyltransferase complex catalytic subunit A Enzyme 2.0E-03 0.670 0.577 4
STT3B Q8TCJ2 STT3 oligosaccharyltransferase complex catalytic subunit B Enzyme 1.00 0.760 0.385 4
TAOK1 Q7L7X3 TAO kinase 1 Kinase 1.00 0.792 0.269 4
TKFC Q3LXA3 triokinase and FMN cyclase 3.2E-12 0.839 0.192 4
UBTF P17480 upstream binding transcription factor 1.00 0.705 0.462 4
ZNF335 Q9H4Z2 zinc finger protein 335 Transcription factor 6.9E-07 0.711 0.462 4
GNB1 P62873 G protein subunit beta 1 Enzyme 1.00 0.617 0.731 5
TBC1D20 Q96BZ9 TBC1 domain family member 20 0.93 0.621 0.500 5