Source: HPO

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
TRMT10C Q7L0Y3 tRNA methyltransferase 10C, mitochondrial RNase P subunit 9.7E-05 0.839 0.154 10
MRPS2 Q9Y399 mitochondrial ribosomal protein S2 Nucleic acid binding 3.1E-07 0.839 0.154 9
PMPCB O75439 peptidase, mitochondrial processing subunit beta Enzyme 4.5E-08 0.769 0.192 16
MRPL3 P09001 mitochondrial ribosomal protein L3 1.3E-12 0.792 0.192 9
TRMT5 Q32P41 tRNA methyltransferase 5 Enzyme 5.0E-02 0.769 0.231 24
MRPS14 O60783 mitochondrial ribosomal protein S14 Nucleic acid binding 1.6E-04 0.805 0.231 16
NFU1 Q9UMS0 NFU1 iron-sulfur cluster scaffold 4.1E-06 0.769 0.231 12
ACAD9 Q9H845 acyl-CoA dehydrogenase family member 9 Enzyme 4.5E-08 0.722 0.269 36
EXOSC8 Q96B26 exosome component 8 Enzyme 6.9E-15 0.736 0.269 12
MED17 Q9NVC6 mediator complex subunit 17 3.1E-09 0.769 0.269 12
GPIHBP1 Q8IV16 glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1 0.14 0.686 0.269 4
NDUFAF1 Q9Y375 NADH:ubiquinone oxidoreductase complex assembly factor 1 3.6E-03 0.700 0.308 50
NDUFA11 Q86Y39 NADH:ubiquinone oxidoreductase subunit A11 1.8E-02 0.705 0.308 47
SLC34A3 Q8N130 solute carrier family 34 member 3 Transporter 5.9E-14 0.695 0.308 43
NDUFB10 O96000 NADH:ubiquinone oxidoreductase subunit B10 4.8E-03 0.729 0.308 39
ACSF3 Q4G176 acyl-CoA synthetase family member 3 Enzyme 2.3E-26 0.743 0.308 27
MCCC1 Q96RQ3 methylcrotonoyl-CoA carboxylase 1 Enzyme 4.0E-12 0.700 0.308 27
GLYCTK Q8IVS8 glycerate kinase Kinase 9.7E-11 0.751 0.308 19
CERS3 Q8IU89 ceramide synthase 3 5.7E-03 0.705 0.308 18
VPS45 Q9NRW7 vacuolar protein sorting 45 homolog Transporter 5.1E-06 0.716 0.308 10
NECAP1 Q8NC96 NECAP endocytosis associated 1 0.13 0.691 0.346 52
NDUFA6 P56556 NADH:ubiquinone oxidoreductase subunit A6 Enzyme 1.3E-04 0.711 0.346 51
AP3B2 Q13367 adaptor related protein complex 3 subunit beta 2 Transporter 0.77 0.691 0.346 51
C12orf65 Q9H3J6 chromosome 12 open reading frame 65 Nucleic acid binding 0.21 0.678 0.346 50