Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
TLR2 O60603 toll like receptor 2 1.0E-06 0.361 0.923 53
PON1 P27169 paraoxonase 1 9.8E-11 0.409 0.885 52
SPP1 P10451 secreted phosphoprotein 1 2.1E-06 0.353 0.885 50
ABCB1 P08183 ATP binding cassette subfamily B member 1 Transporter 1.3E-05 0.344 0.885 49
MIF P14174 macrophage migration inhibitory factor 1.2E-02 0.412 0.885 49
MMP1 P03956 matrix metallopeptidase 1 Enzyme 7.7E-18 0.385 0.885 48
HLA-G P17693 major histocompatibility complex, class I, G 1.4E-11 0.461 0.769 46
CD14 P08571 CD14 molecule 4.9E-05 0.392 0.885 43
SLC6A4 P31645 solute carrier family 6 member 4 Transporter 0.25 0.429 0.808 41
MLH1 P40692 mutL homolog 1 Nucleic acid binding 3.4E-05 0.399 0.808 40
CD40LG P29965 CD40 ligand Signaling 0.72 0.414 0.846 39
CD40 P25942 CD40 molecule 0.85 0.396 0.846 36
CXCL10 P02778 C-X-C motif chemokine ligand 10 Signaling 0.37 0.378 0.885 36
FOXP3 Q9BZS1 forkhead box P3 0.99 0.368 0.846 36
MMP7 P09237 matrix metallopeptidase 7 Enzyme 1.0E-09 0.446 0.885 36
LEPR P48357 leptin receptor Signaling 0.99 0.433 0.808 33
IGF2 P01344 insulin like growth factor 2 4.4E-02 0.390 0.885 31
TNFRSF1B P20333 TNF receptor superfamily member 1B 0.50 0.425 0.885 29
IL12B P29460 interleukin 12B Signaling 1.1E-04 0.480 0.885 28
IL13 P35225 interleukin 13 1.4E-02 0.386 0.846 28
LPL P06858 lipoprotein lipase Enzyme 1.3E-09 0.474 0.808 28
SOCS1 O15524 suppressor of cytokine signaling 1 Enzyme modulator 0.59 0.445 0.808 26
NOD2 Q9HC29 nucleotide binding oligomerization domain containing 2 Enzyme 2.0E-30 0.423 0.923 25
RELA Q04206 RELA proto-oncogene, NF-kB subunit Transcription factor 1.00 0.406 0.885 24