Source: CURATED

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
ADORA2A P29274 adenosine A2a receptor G-protein coupled receptor 0.60 0.526 0.769 101 0
TRH P20396 thyrotropin releasing hormone 8.9E-04 0.519 0.846 100 1
CCND1 P24385 cyclin D1 Enzyme modulator 0.89 0.344 0.923 96 6
CYP2D6 P10635 cytochrome P450 family 2 subfamily D member 6 1.1E-25 0.437 0.885 93 2
HTR1A P08908 5-hydroxytryptamine receptor 1A G-protein coupled receptor 0.20 0.522 0.846 93 1
NOS1 P29475 nitric oxide synthase 1 1.00 0.408 0.885 89 9
HIF1A Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 0.98 0.327 0.923 89 2
FGFR1 P11362 fibroblast growth factor receptor 1 Kinase 1.00 0.362 0.885 87 79
GDNF P39905 glial cell derived neurotrophic factor Signaling 0.20 0.434 0.885 85 5
ABCB1 P08183 ATP binding cassette subfamily B member 1 Transporter 1.3E-05 0.344 0.885 84 4
COMT P21964 catechol-O-methyltransferase Enzyme 1.1E-06 0.400 0.923 82 6
FGF2 P09038 fibroblast growth factor 2 Signaling 1.8E-02 0.383 0.923 81 2
CRP P02741 C-reactive protein 3.7E-03 0.299 0.962 80 6
AVP P01185 arginine vasopressin Signaling 7.4E-02 0.437 0.846 78 18
SLC6A4 P31645 solute carrier family 6 member 4 Transporter 0.25 0.429 0.808 75 6
ESR2 Q92731 estrogen receptor 2 Nuclear receptor 4.5E-08 0.400 0.923 73 19
TERT O14746 telomerase reverse transcriptase Enzyme 0.99 0.374 0.846 72 75
MTOR P42345 mechanistic target of rapamycin kinase Kinase 1.00 0.343 0.885 68 36
GHRL Q9UBU3 ghrelin and obestatin prepropeptide 1.4E-11 0.517 0.769 68 4
DRD3 P35462 dopamine receptor D3 G-protein coupled receptor 2.4E-03 0.529 0.692 67 0
HP P00738 haptoglobin Enzyme 1.7E-05 0.412 0.885 62 2
HTR2A P28223 5-hydroxytryptamine receptor 2A G-protein coupled receptor 0.51 0.473 0.846 60 1
NTRK2 Q16620 neurotrophic receptor tyrosine kinase 2 Kinase 1.00 0.479 0.808 58 9
SST P61278 somatostatin Signaling 0.34 0.399 0.885 56 0