| Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI g | DPI g | Num. diseases | Num. SNPs |
|---|---|---|---|---|---|---|---|---|
| BTK | Q06187 | Bruton tyrosine kinase | Kinase | 1.00 | 0.464 | 0.808 | 8 | 83 |
| SF3B1 | O75533 | splicing factor 3b subunit 1 | Nucleic acid binding | 1.00 | 0.511 | 0.731 | 8 | 9 |
| BARD1 | Q99728 | BRCA1 associated RING domain 1 | 1.4E-24 | 0.597 | 0.538 | 7 | 145 | |
| RHOA | P61586 | ras homolog family member A | Enzyme modulator | 0.60 | 0.502 | 0.808 | 7 | 4 |
| ALK | Q9UM73 | ALK receptor tyrosine kinase | Kinase | 3.2E-06 | 0.396 | 0.846 | 6 | 21 |
| XPO1 | O14980 | exportin 1 | Receptor | 1.00 | 0.504 | 0.692 | 5 | 2 |
| ESR1 | P03372 | estrogen receptor 1 | Nuclear receptor | 1.00 | 0.324 | 0.962 | 4 | 11 |
| FGFR4 | P22455 | fibroblast growth factor receptor 4 | Kinase | 7.2E-13 | 0.490 | 0.769 | 3 | 4 |
| ROCK1 | Q13464 | Rho associated coiled-coil containing protein kinase 1 | Kinase | 1.00 | 0.513 | 0.731 | 2 | 1 |