| Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI g | DPI g | Num. diseases | Num. SNPs |
|---|---|---|---|---|---|---|---|---|
| FGFR4 | P22455 | fibroblast growth factor receptor 4 | Kinase | 7.2E-13 | 0.490 | 0.769 | 3 | 4 |
| ROCK1 | Q13464 | Rho associated coiled-coil containing protein kinase 1 | Kinase | 1.00 | 0.513 | 0.731 | 2 | 1 |
| ESR1 | P03372 | estrogen receptor 1 | Nuclear receptor | 1.00 | 0.324 | 0.962 | 4 | 11 |
| BRCA2 | P51587 | BRCA2 DNA repair associated | Nucleic acid binding | 2.4E-25 | 0.379 | 0.846 | 68 | 2953 |
| SF3B1 | O75533 | splicing factor 3b subunit 1 | Nucleic acid binding | 1.00 | 0.511 | 0.731 | 8 | 9 |
| XPO1 | O14980 | exportin 1 | Receptor | 1.00 | 0.504 | 0.692 | 5 | 2 |
| TP53 | P04637 | tumor protein p53 | Transcription factor | 0.53 | 0.236 | 0.962 | 84 | 390 |
| MED12 | Q93074 | mediator complex subunit 12 | Transcription factor | 1.00 | 0.476 | 0.769 | 25 | 18 |
| SMAD4 | Q13485 | SMAD family member 4 | Transcription factor | 1.00 | 0.401 | 0.808 | 16 | 133 |