Source: LHGDN

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
ESR1 P03372 estrogen receptor 1 Nuclear receptor 1.00 0.324 0.962 71
ADIPOQ Q15848 adiponectin, C1Q and collagen domain containing 4.6E-09 0.376 0.885 67
IL4 P05112 interleukin 4 4.7E-03 0.332 0.962 67
FASLG P48023 Fas ligand Signaling 0.18 0.430 0.885 66
TERT O14746 telomerase reverse transcriptase Enzyme 0.99 0.374 0.846 66
CCND1 P24385 cyclin D1 Enzyme modulator 0.89 0.344 0.923 65
STAT3 P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1.00 0.320 0.923 64
EDN1 P05305 endothelin 1 Signaling 0.46 0.380 0.846 63
GSTM1 P09488 glutathione S-transferase mu 1 2.1E-03 0.380 0.923 62
VDR P11473 vitamin D receptor Nuclear receptor 1.7E-05 0.352 0.885 61
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962 60
CDKN1A P38936 cyclin dependent kinase inhibitor 1A 1.9E-03 0.403 0.769 59
HIF1A Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 0.98 0.327 0.923 59
GSTP1 P09211 glutathione S-transferase pi 1 1.4E-02 0.383 0.923 58
GSTT1 P30711 glutathione S-transferase theta 1 1.5E-04 0.393 0.923 55
IL1RN P18510 interleukin 1 receptor antagonist 3.1E-02 0.373 0.923 55
TNFSF10 P50591 TNF superfamily member 10 Signaling 0.13 0.413 0.885 54
CTNNB1 P35222 catenin beta 1 1.00 0.303 0.885 53
CXCL12 P48061 C-X-C motif chemokine ligand 12 0.12 0.379 0.846 53
CDKN1B P46527 cyclin dependent kinase inhibitor 1B 0.62 0.409 0.769 52
MMP3 P08254 matrix metallopeptidase 3 Enzyme 5.7E-15 0.408 0.885 52
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923 51
BIRC5 O15392 baculoviral IAP repeat containing 5 Enzyme modulator 5.6E-02 0.495 0.731 50
CDH1 P12830 cadherin 1 0.15 0.401 0.808 50