Source: LHGDN

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
SPP1 P10451 secreted phosphoprotein 1 2.1E-06 0.353 0.885 50
TNFRSF11B O00300 TNF receptor superfamily member 11b 0.16 0.422 0.808 50
ABCB1 P08183 ATP binding cassette subfamily B member 1 Transporter 1.3E-05 0.344 0.885 49
CCL5 P13501 C-C motif chemokine ligand 5 Signaling 1.8E-03 0.403 0.885 49
CXCR4 P61073 C-X-C motif chemokine receptor 4 G-protein coupled receptor 1.8E-02 0.362 0.923 49
MIF P14174 macrophage migration inhibitory factor 1.2E-02 0.412 0.885 49
SELE P16581 selectin E 7.9E-10 0.447 0.808 49
MMP1 P03956 matrix metallopeptidase 1 Enzyme 7.7E-18 0.385 0.885 48
CD44 P16070 CD44 molecule (Indian blood group) 2.4E-07 0.363 0.962 47
BCL2L1 Q07817 BCL2 like 1 Signaling 0.94 0.493 0.885 46
CASP3 P42574 caspase 3 Enzyme 0.10 0.351 0.923 46
HLA-G P17693 major histocompatibility complex, class I, G 1.4E-11 0.461 0.769 46
PLAU P00749 plasminogen activator, urokinase Enzyme 2.3E-06 0.425 0.923 46
BAX Q07812 BCL2 associated X, apoptosis regulator Signaling 0.32 0.417 0.885 44
GHRL Q9UBU3 ghrelin and obestatin prepropeptide 1.4E-11 0.517 0.769 43
IGFBP3 P17936 insulin like growth factor binding protein 3 Enzyme modulator 0.91 0.439 0.808 43
AGER Q15109 advanced glycosylation end-product specific receptor Receptor 6.4E-16 0.420 0.885 42
MET P08581 MET proto-oncogene, receptor tyrosine kinase Kinase 0.97 0.380 0.846 42
HLA-B P01889 major histocompatibility complex, class I, B 3.9E-05 0.379 0.885 41
MDM2 Q00987 MDM2 proto-oncogene Nucleic acid binding 1.00 0.362 0.846 41
CYP1A1 P04798 cytochrome P450 family 1 subfamily A member 1 Enzyme 1.1E-17 0.436 0.846 40
MAPK1 P28482 mitogen-activated protein kinase 1 Kinase 1.00 0.330 0.923 40
MLH1 P40692 mutL homolog 1 Nucleic acid binding 3.4E-05 0.399 0.808 40
CD40LG P29965 CD40 ligand Signaling 0.72 0.414 0.846 39