Source: BEFREE

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
JAG1 P78504 jagged canonical Notch ligand 1 1.00 0.429 0.808 322 5
BCR P11274 BCR activator of RhoGEF and GTPase Enzyme modulator 0.99 0.431 0.885 319 6
RUNX3 Q13761 RUNX family transcription factor 3 Transcription factor 0.84 0.459 0.731 256 8
MYCN P04198 MYCN proto-oncogene, bHLH transcription factor Transcription factor 0.89 0.454 0.808 253 7
RARA P10276 retinoic acid receptor alpha Nuclear receptor 0.96 0.470 0.846 225 3
ATR Q13535 ATR serine/threonine kinase Kinase 3.5E-09 0.456 0.923 223 7
SYK P43405 spleen associated tyrosine kinase Kinase 1.00 0.475 0.808 219 4
CAD P27708 carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase Enzyme 1.00 0.482 0.846 216 3
PML P29590 promyelocytic leukemia 0.21 0.477 0.846 210 5
PAX5 Q02548 paired box 5 1.00 0.487 0.654 191 9
B3GAT1 Q9P2W7 beta-1,3-glucuronyltransferase 1 Enzyme 0.14 0.494 0.769 191 0
CTNND1 O60716 catenin delta 1 Cellular structure 1.00 0.500 0.808 174 1
ASXL1 Q8IXJ9 ASXL transcriptional regulator 1 1.3E-14 0.482 0.808 165 2
BCAR1 P56945 BCAR1 scaffold protein, Cas family member 1.00 0.518 0.846 163 1
LBR Q14739 lamin B receptor Enzyme 0.18 0.473 0.808 161 2
CSE1L P55060 chromosome segregation 1 like Enzyme modulator 1.00 0.521 0.808 157 0
AURKB Q96GD4 aurora kinase B Kinase 4.5E-03 0.510 0.769 154 3
UROD P06132 uroporphyrinogen decarboxylase 1.3E-08 0.521 0.769 146 6
TMX2-CTNND1 TMX2-CTNND1 readthrough (NMD candidate) 0.538 0.769 138 2
S100A10 P60903 S100 calcium binding protein A10 Calcium-binding protein 0.17 0.528 0.769 135 1
PPM1D O15297 protein phosphatase, Mg2+/Mn2+ dependent 1D Enzyme 2.2E-11 0.513 0.808 135 0
RUNX1T1 Q06455 RUNX1 partner transcriptional co-repressor 1 Transcription factor 0.98 0.530 0.808 133 5
RTL1 A6NKG5 retrotransposon Gag like 1 5.6E-03 0.554 0.808 117 0
TCL1A P56279 T cell leukemia/lymphoma 1A 5.7E-10 0.558 0.500 105 2