Source: LHGDN

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
RB1 P06400 RB transcriptional corepressor 1 Nucleic acid binding 1.00 0.444 0.885 39
SOD2 P04179 superoxide dismutase 2 Enzyme 0.15 0.379 0.923 39
MKI67 P46013 marker of proliferation Ki-67 1.3E-28 0.431 0.808 38
ESR2 Q92731 estrogen receptor 2 Nuclear receptor 4.5E-08 0.400 0.923 37
ITGB3 P05106 integrin subunit beta 3 Receptor 1.7E-03 0.485 0.846 37
CD40 P25942 CD40 molecule 0.85 0.396 0.846 36
FOXP3 Q9BZS1 forkhead box P3 0.99 0.368 0.846 36
MAPK14 Q16539 mitogen-activated protein kinase 14 Kinase 0.37 0.379 0.923 36
MMP7 P09237 matrix metallopeptidase 7 Enzyme 1.0E-09 0.446 0.885 36
FLT1 P17948 fms related receptor tyrosine kinase 1 Kinase 1.00 0.419 0.846 35
MPO P05164 myeloperoxidase Enzyme 7.1E-15 0.377 0.923 35
MSH2 P43246 mutS homolog 2 Nucleic acid binding 0.90 0.406 0.808 35
PLAUR Q03405 plasminogen activator, urokinase receptor 5.3E-03 0.536 0.731 35
ITGB1 P05556 integrin subunit beta 1 Receptor 0.98 0.496 0.808 34
PDGFRA P16234 platelet derived growth factor receptor alpha Kinase 1.00 0.415 0.808 34
CASP8 Q14790 caspase 8 Enzyme 3.7E-06 0.404 0.923 33
NAT2 P11245 N-acetyltransferase 2 Enzyme 3.3E-06 0.451 0.885 33
ATM Q13315 ATM serine/threonine kinase Kinase 5.6E-47 0.374 0.885 32
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1.00 0.319 0.846 32
APOA1 P02647 apolipoprotein A1 5.5E-04 0.429 0.885 31
LTA P01374 lymphotoxin alpha Signaling 0.20 0.434 0.885 31
MTOR P42345 mechanistic target of rapamycin kinase Kinase 1.00 0.343 0.885 31
SLC2A1 P11166 solute carrier family 2 member 1 Transporter 0.99 0.388 0.808 31
THBS1 P07996 thrombospondin 1 1.00 0.407 0.885 31