Source: ANIMAL_MODELS

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962 101
CCL2 P13500 C-C motif chemokine ligand 2 Signaling 0.61 0.321 0.962 94
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962 92
PTGS2 P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1.00 0.314 0.962 76
IL10 P22301 interleukin 10 5.9E-03 0.281 0.923 59
IL6 P05231 interleukin 6 0.32 0.248 0.962 54
HIF1A Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 0.98 0.327 0.923 47
NOS1 P29475 nitric oxide synthase 1 1.00 0.408 0.885 46
MTOR P42345 mechanistic target of rapamycin kinase Kinase 1.00 0.343 0.885 44
AGER Q15109 advanced glycosylation end-product specific receptor Receptor 6.4E-16 0.420 0.885 43
CAT P04040 catalase Enzyme 1.6E-10 0.359 0.962 41
IL18 Q14116 interleukin 18 3.1E-02 0.365 0.923 41
TLR4 O00206 toll like receptor 4 4.6E-09 0.321 0.962 41
BECN1 Q14457 beclin 1 Enzyme modulator 0.94 0.432 0.846 40
CCL5 P13501 C-C motif chemokine ligand 5 Signaling 1.8E-03 0.403 0.885 40
MFN2 O95140 mitofusin 2 Enzyme 0.99 0.471 0.846 38
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923 35
C3 P01024 complement C3 Enzyme modulator 0.90 0.445 0.885 34
ANXA1 P04083 annexin A1 1.2E-07 0.442 0.885 30
GJA1 P17302 gap junction protein alpha 1 Cell-cell junction 0.16 0.393 0.885 28
CX3CL1 P78423 C-X3-C motif chemokine ligand 1 Signaling 0.61 0.478 0.808 27
CX3CR1 P49238 C-X3-C motif chemokine receptor 1 G-protein coupled receptor 6.1E-02 0.457 0.885 27
IL17A Q16552 interleukin 17A 4.3E-02 0.324 0.923 27
CCR5 P51681 C-C motif chemokine receptor 5 (gene/pseudogene) G-protein coupled receptor 4.3E-10 0.398 0.885 26