Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
BRCA1 DNA repair associated | 0.367 | 0.923 | 9.2E-29 |
|
disease | 0.700 | None | 0.965 | 72 | 0 | 1992 | 2020 | ||||||||
|
BRCA2 DNA repair associated | 0.379 | 0.846 | 2.4E-25 |
|
disease | 0.900 | None | 0.947 | 51 | 0 | 1994 | 2020 | ||||||||
|
tumor protein p53 | 0.236 | 0.962 | 0.53 |
|
disease | 0.700 | None | 0.963 | 14 | 0 | 1991 | 2020 | ||||||||
|
epidermal growth factor receptor | 0.295 | 0.885 | 0.37 |
|
disease | 0.400 | None | 1.000 | 12 | 0 | 1995 | 2019 | ||||||||
|
erb-b2 receptor tyrosine kinase 2 | 0.328 | 0.923 | 6.0E-03 |
|
disease | 0.700 | None | 0.951 | 10 | 0 | 1989 | 2019 | ||||||||
|
vascular endothelial growth factor A | 0.266 | 0.923 | 2.4E-05 |
|
disease | 0.100 | None | 0.973 | 10 | 0 | 1996 | 2019 | ||||||||
|
prostaglandin-endoperoxide synthase 2 | 0.314 | 0.962 | 1.00 |
|
disease | 0.100 | None | 1.000 | 6 | 0 | 2001 | 2019 | ||||||||
|
mucin 16, cell surface associated | 0.479 | 0.808 | 8.3E-112 |
|
disease | 0.400 | None | 1.000 | 5 | 0 | 1987 | 2020 | ||||||||
|
aurora kinase A | 0.475 | 0.731 | 0.87 |
|
disease | 0.090 | None | 1.000 | 5 | 0 | 2002 | 2016 | ||||||||
|
mutL homolog 1 | 0.399 | 0.808 | 3.4E-05 |
|
disease | 0.700 | None | 0.950 | 4 | 0 | 1994 | 2019 | ||||||||
|
signal transducer and activator of transcription 3 | 0.320 | 0.923 | 1.00 |
|
disease | 0.400 | None | 1.000 | 4 | 0 | 2004 | 2019 | ||||||||
|
cyclin dependent kinase inhibitor 2A | 0.300 | 0.885 | 0.39 |
|
disease | 0.100 | None | 0.967 | 4 | 0 | 1995 | 2019 | ||||||||
|
cyclin dependent kinase inhibitor 1A | 0.403 | 0.769 | 1.9E-03 |
|
disease | 0.100 | None | 1.000 | 4 | 0 | 1999 | 2015 | ||||||||
|
matrix metallopeptidase 9 | 0.305 | 0.923 | 1.9E-17 |
|
disease | 0.100 | None | 1.000 | 4 | 0 | 1998 | 2018 | ||||||||
|
transforming growth factor beta 1 | 0.287 | 0.962 | 3.7E-02 |
|
disease | 0.100 | None | 1.000 | 4 | 0 | 1992 | 2019 | ||||||||
|
ERCC excision repair 1, endonuclease non-catalytic subunit | 0.445 | 0.846 | 1.6E-07 |
|
disease | 0.100 | None | 0.944 | 4 | 0 | 1997 | 2019 | ||||||||
|
androgen receptor | 0.351 | 0.846 | 0.99 |
|
disease | 0.100 | None | 0.895 | 4 | 0 | 1999 | 2019 | ||||||||
|
EMSY transcriptional repressor, BRCA2 interacting | 0.628 | 0.423 | 1.00 |
|
disease | 0.070 | None | 0.857 | 4 | 0 | 2003 | 2017 | ||||||||
|
integrin linked kinase | 0.503 | 0.769 | 3.8E-05 |
|
disease | 0.060 | None | 1.000 | 4 | 0 | 2003 | 2017 | ||||||||
|
ribosomal protein S6 kinase B1 | 0.511 | 0.731 | 0.97 |
|
disease | 0.060 | None | 1.000 | 4 | 0 | 2004 | 2013 | ||||||||
|
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | 0.292 | 0.923 | 1.00 |
|
disease | 0.700 | None | 0.984 | 3 | 0 | 1999 | 2019 | ||||||||
|
B-Raf proto-oncogene, serine/threonine kinase | 0.319 | 0.846 | 1.00 |
|
disease | 0.500 | None | 0.958 | 3 | 0 | 2002 | 2019 | ||||||||
|
mitogen-activated protein kinase 1 | 0.330 | 0.923 | 1.00 |
|
disease | 0.400 | None | 1.000 | 3 | 0 | 2004 | 2019 | ||||||||
|
tubulin beta 3 class III | 0.486 | 0.808 | 2.6E-10 |
|
disease | 0.390 | None | 1.000 | 3 | 0 | 2005 | 2019 | ||||||||
|
baculoviral IAP repeat containing 5 | 0.495 | 0.731 | 5.6E-02 |
|
disease | 0.370 | None | 1.000 | 3 | 0 | 2005 | 2019 |