Source: LHGDN

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 2950
Gene Symbol: GSTP1
GSTP1
CUI: C0005695
Disease: Bladder Neoplasm
Bladder Neoplasm
0.600 GeneticVariation LHGDN Data indicated that in Caucasians exposed to aromatic amines the GSTP1 A1578G polymorphism did not appear to play a significant role as a predisposing factor for bladder cancer incidence. 18569592

2008

Entrez Id: 2950
Gene Symbol: GSTP1
GSTP1
CUI: C0005695
Disease: Bladder Neoplasm
Bladder Neoplasm
0.600 GeneticVariation LHGDN No association was found between the genetic polymorphisms investigated and BC risk according to coffee consumption apart of a significant increased BC risk among GSTP1 105-114 Val carriers heavy coffee drinkers (>3 cups/day) (OR 3.18, 95% CI 1.06-9.55). 18365755

2008

Entrez Id: 2950
Gene Symbol: GSTP1
GSTP1
CUI: C0005695
Disease: Bladder Neoplasm
Bladder Neoplasm
0.600 GeneticVariation LHGDN GSTM1, GSTT1 and GSTP1 genotype frequencies were determined in bladder cancer cases (n=72) and healthy controls with no history of malignancies (n=82) using PCR-based techniques. 15832776

2005

Entrez Id: 2950
Gene Symbol: GSTP1
GSTP1
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
0.600 GeneticVariation LHGDN CYP1B1, CYP1A1, MPO, and GSTP1 polymorphisms and lung cancer risk in never-smoking Korean women. 17980933

2008

Entrez Id: 2950
Gene Symbol: GSTP1
GSTP1
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
0.600 GeneticVariation LHGDN Genetic polymorphisms of glutathione S-transferases as modulators of lung cancer susceptibility. 12189190

2002

Entrez Id: 2950
Gene Symbol: GSTP1
GSTP1
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
0.600 Biomarker LHGDN Genetic determinants of lung cancer short-term survival: the role of glutathione-related genes. 11844594

2002

Entrez Id: 2950
Gene Symbol: GSTP1
GSTP1
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
0.600 AlteredExpression LHGDN Identification of postoperative adjuvant chemotherapy responders in non-small cell lung cancer by novel biomarker. 15900595

2005

Entrez Id: 2950
Gene Symbol: GSTP1
GSTP1
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
0.600 GeneticVariation LHGDN Glutathione S-transferase M1 and P1 metabolic polymorphism and lung cancer predisposition. 14628089

2003

Entrez Id: 2950
Gene Symbol: GSTP1
GSTP1
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
0.600 Biomarker LHGDN Smoking and the risk of lung cancer: susceptibility with GSTP1 polymorphisms. 14501269

2003

Entrez Id: 2950
Gene Symbol: GSTP1
GSTP1
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
0.600 GeneticVariation LHGDN Associations between carcinogen-DNA damage, glutathione S-transferase genotypes, and risk of lung cancer in the prospective Physicians' Health Cohort Study. 12376472

2002

Entrez Id: 2950
Gene Symbol: GSTP1
GSTP1
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
0.600 AlteredExpression LHGDN Expression of glutathione S-transferase pi and glutathione synthase correlates with survival in early stage non-small cell carcinomas of the lung. 17234469

2007

Entrez Id: 2950
Gene Symbol: GSTP1
GSTP1
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
0.600 AlteredExpression LHGDN Transcripts in pretreatment biopsies from a three-arm randomized trial in metastatic non-small-cell lung cancer. 12789263

2003

Entrez Id: 2950
Gene Symbol: GSTP1
GSTP1
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
0.600 GeneticVariation LHGDN Combined effects of genetic polymorphisms in six selected genes on lung cancer susceptibility. 17428572

2007

Entrez Id: 2950
Gene Symbol: GSTP1
GSTP1
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
0.600 GeneticVariation LHGDN Combined effect of GSTM1, GSTT1 and GSTP1 polymorphisms on histological subtypes of lung cancer. 18415801

2008

Entrez Id: 2950
Gene Symbol: GSTP1
GSTP1
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
0.600 GeneticVariation LHGDN A literature review of molecular markers predictive of clinical response to cytotoxic chemotherapy in patients with lung cancer. 17409824

2006

Entrez Id: 2950
Gene Symbol: GSTP1
GSTP1
CUI: C0004096
Disease: Asthma
Asthma
0.400 GeneticVariation LHGDN The effect of GSTM1 null/present genotype on the association between GSTP1 Ile105Val and asthma was also investigated. 17643058

2007

Entrez Id: 2950
Gene Symbol: GSTP1
GSTP1
CUI: C0004096
Disease: Asthma
Asthma
0.400 GeneticVariation LHGDN The associations of GSTP1 variants with asthma and wheezing were assessed among white children in the Children's Health Study (CHS). 18335111

2008

Entrez Id: 2950
Gene Symbol: GSTP1
GSTP1
CUI: C0004096
Disease: Asthma
Asthma
0.400 GeneticVariation LHGDN Subjects with the GSTP1 homozygous Val/Val genotype had a 3.55-fold increased risk of having atopic asthma compared to nonatopic asthma (OR = 3.55; 95% CI, 1.10-12.56). 15612961

2004

Entrez Id: 2950
Gene Symbol: GSTP1
GSTP1
CUI: C0004096
Disease: Asthma
Asthma
0.400 GeneticVariation LHGDN GSTM1 null was independently associated with an increased risk of asthma and showed little variation with air pollution or GSTP1 genotype. 18988661

2009

Entrez Id: 2950
Gene Symbol: GSTP1
GSTP1
CUI: C0004096
Disease: Asthma
Asthma
0.400 Biomarker LHGDN These data suggest that homozygosity for the GSTP1*Val allele confers protection against TDI-induced asthma and airway hyperresponsiveness. 11994713

2002

Entrez Id: 2950
Gene Symbol: GSTP1
GSTP1
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.400 GeneticVariation LHGDN Gluthatione-S-transferase P1 polymorphism I105V in familial and sporadic prostate cancer. 15527908

2004

Entrez Id: 2950
Gene Symbol: GSTP1
GSTP1
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.400 GeneticVariation LHGDN Association of CYP17, GSTP1, and PON1 polymorphisms with the risk of prostate cancer. 15538743

2005

Entrez Id: 2950
Gene Symbol: GSTP1
GSTP1
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.400 PosttranslationalModification LHGDN Hypermethylation of the CpG islands in the promoter region flanking GSTP1 gene is a potential plasma DNA biomarker for detecting prostate carcinoma. 17291695

2007

Entrez Id: 2950
Gene Symbol: GSTP1
GSTP1
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.400 AlteredExpression LHGDN Glutathione S-transferase pi is upregulated in the stromal compartment of hormone independent prostate cancer. 12746833

2003

Entrez Id: 2950
Gene Symbol: GSTP1
GSTP1
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.400 AlteredExpression LHGDN Reversal of GSTP1 CpG island hypermethylation and reactivation of pi-class glutathione S-transferase (GSTP1) expression in human prostate cancer cells by treatment with procainamide. 11751372

2001