×
Entrez Id:
2950
Gene Symbol:
GSTP1
GSTP1
Bladder Neoplasm
0.600
GeneticVariation
LHGDN
Data indicated that in Caucasians exposed to aromatic amines the GSTP1 A1578G polymorphism did not appear to play a significant role as a predisposing factor for bladder cancer incidence.
18569592
2008
×
Entrez Id:
2950
Gene Symbol:
GSTP1
GSTP1
Bladder Neoplasm
0.600
GeneticVariation
LHGDN
No association was found between the genetic polymorphisms investigated and BC risk according to coffee consumption apart of a significant increased BC risk among GSTP1 105-114 Val carriers heavy coffee drinkers (>3 cups/day) (OR 3.18, 95% CI 1.06-9.55).
18365755
2008
×
Entrez Id:
2950
Gene Symbol:
GSTP1
GSTP1
Bladder Neoplasm
0.600
GeneticVariation
LHGDN
GSTM1, GSTT1 and GSTP1 genotype frequencies were determined in bladder cancer cases (n=72) and healthy controls with no history of malignancies (n=82) using PCR-based techniques.
15832776
2005
×
Entrez Id:
2950
Gene Symbol:
GSTP1
GSTP1
Lung Neoplasms
0.600
GeneticVariation
LHGDN
CYP1B1, CYP1A1, MPO, and GSTP1 polymorphisms and lung cancer risk in never-smoking Korean women.
17980933
2008
×
Entrez Id:
2950
Gene Symbol:
GSTP1
GSTP1
Lung Neoplasms
0.600
GeneticVariation
LHGDN
Genetic polymorphisms of glutathione S-transferases as modulators of lung cancer susceptibility.
12189190
2002
×
Entrez Id:
2950
Gene Symbol:
GSTP1
GSTP1
Lung Neoplasms
0.600
Biomarker
LHGDN
Genetic determinants of lung cancer short-term survival: the role of glutathione-related genes.
11844594
2002
×
Entrez Id:
2950
Gene Symbol:
GSTP1
GSTP1
Lung Neoplasms
0.600
AlteredExpression
LHGDN
Identification of postoperative adjuvant chemotherapy responders in non-small cell lung cancer by novel biomarker.
15900595
2005
×
Entrez Id:
2950
Gene Symbol:
GSTP1
GSTP1
Lung Neoplasms
0.600
GeneticVariation
LHGDN
Glutathione S-transferase M1 and P1 metabolic polymorphism and lung cancer predisposition.
14628089
2003
×
Entrez Id:
2950
Gene Symbol:
GSTP1
GSTP1
Lung Neoplasms
0.600
Biomarker
LHGDN
Smoking and the risk of lung cancer: susceptibility with GSTP1 polymorphisms.
14501269
2003
×
Entrez Id:
2950
Gene Symbol:
GSTP1
GSTP1
Lung Neoplasms
0.600
GeneticVariation
LHGDN
Associations between carcinogen-DNA damage, glutathione S-transferase genotypes, and risk of lung cancer in the prospective Physicians' Health Cohort Study.
12376472
2002
×
Entrez Id:
2950
Gene Symbol:
GSTP1
GSTP1
Lung Neoplasms
0.600
AlteredExpression
LHGDN
Expression of glutathione S-transferase pi and glutathione synthase correlates with survival in early stage non-small cell carcinomas of the lung.
17234469
2007
×
Entrez Id:
2950
Gene Symbol:
GSTP1
GSTP1
Lung Neoplasms
0.600
AlteredExpression
LHGDN
Transcripts in pretreatment biopsies from a three-arm randomized trial in metastatic non-small-cell lung cancer.
12789263
2003
×
Entrez Id:
2950
Gene Symbol:
GSTP1
GSTP1
Lung Neoplasms
0.600
GeneticVariation
LHGDN
Combined effects of genetic polymorphisms in six selected genes on lung cancer susceptibility.
17428572
2007
×
Entrez Id:
2950
Gene Symbol:
GSTP1
GSTP1
Lung Neoplasms
0.600
GeneticVariation
LHGDN
Combined effect of GSTM1, GSTT1 and GSTP1 polymorphisms on histological subtypes of lung cancer.
18415801
2008
×
Entrez Id:
2950
Gene Symbol:
GSTP1
GSTP1
Lung Neoplasms
0.600
GeneticVariation
LHGDN
A literature review of molecular markers predictive of clinical response to cytotoxic chemotherapy in patients with lung cancer.
17409824
2006
×
Entrez Id:
2950
Gene Symbol:
GSTP1
GSTP1
Asthma
0.400
GeneticVariation
LHGDN
The effect of GSTM1 null/present genotype on the association between GSTP1 Ile105Val and asthma was also investigated.
17643058
2007
×
Entrez Id:
2950
Gene Symbol:
GSTP1
GSTP1
Asthma
0.400
GeneticVariation
LHGDN
The associations of GSTP1 variants with asthma and wheezing were assessed among white children in the Children's Health Study (CHS).
18335111
2008
×
Entrez Id:
2950
Gene Symbol:
GSTP1
GSTP1
Asthma
0.400
GeneticVariation
LHGDN
Subjects with the GSTP1 homozygous Val/Val genotype had a 3.55-fold increased risk of having atopic asthma compared to nonatopic asthma (OR = 3.55; 95% CI, 1.10-12.56).
15612961
2004
×
Entrez Id:
2950
Gene Symbol:
GSTP1
GSTP1
Asthma
0.400
GeneticVariation
LHGDN
GSTM1 null was independently associated with an increased risk of asthma and showed little variation with air pollution or GSTP1 genotype.
18988661
2009
×
Entrez Id:
2950
Gene Symbol:
GSTP1
GSTP1
Asthma
0.400
Biomarker
LHGDN
These data suggest that homozygosity for the GSTP1 *Val allele confers protection against TDI-induced asthma and airway hyperresponsiveness.
11994713
2002
×
Entrez Id:
2950
Gene Symbol:
GSTP1
GSTP1
Prostatic Neoplasms
0.400
GeneticVariation
LHGDN
Gluthatione-S-transferase P1 polymorphism I105V in familial and sporadic prostate cancer.
15527908
2004
×
Entrez Id:
2950
Gene Symbol:
GSTP1
GSTP1
Prostatic Neoplasms
0.400
GeneticVariation
LHGDN
Association of CYP17, GSTP1, and PON1 polymorphisms with the risk of prostate cancer.
15538743
2005
×
Entrez Id:
2950
Gene Symbol:
GSTP1
GSTP1
Prostatic Neoplasms
0.400
PosttranslationalModification
LHGDN
Hypermethylation of the CpG islands in the promoter region flanking GSTP1 gene is a potential plasma DNA biomarker for detecting prostate carcinoma.
17291695
2007
×
Entrez Id:
2950
Gene Symbol:
GSTP1
GSTP1
Prostatic Neoplasms
0.400
AlteredExpression
LHGDN
Glutathione S-transferase pi is upregulated in the stromal compartment of hormone independent prostate cancer.
12746833
2003
×
Entrez Id:
2950
Gene Symbol:
GSTP1
GSTP1
Prostatic Neoplasms
0.400
AlteredExpression
LHGDN
Reversal of GSTP1 CpG island hypermethylation and reactivation of pi-class glutathione S-transferase (GSTP1) expression in human prostate cancer cells by treatment with procainamide.
11751372
2001