Source: LHGDN

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 2950
Gene Symbol: GSTP1
GSTP1
CUI: C0005695
Disease: Bladder Neoplasm
Bladder Neoplasm 		0.600 GeneticVariation LHGDN Data indicated that in Caucasians exposed to aromatic amines the GSTP1 A1578G polymorphism did not appear to play a significant role as a predisposing factor for bladder cancer incidence. 18569592

2008
Entrez Id: 2950
Gene Symbol: GSTP1
GSTP1
CUI: C0005695
Disease: Bladder Neoplasm
Bladder Neoplasm 		0.600 GeneticVariation LHGDN No association was found between the genetic polymorphisms investigated and BC risk according to coffee consumption apart of a significant increased BC risk among GSTP1 105-114 Val carriers heavy coffee drinkers (>3 cups/day) (OR 3.18, 95% CI 1.06-9.55). 18365755

2008
Entrez Id: 2950
Gene Symbol: GSTP1
GSTP1
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms 		0.600 GeneticVariation LHGDN CYP1B1, CYP1A1, MPO, and GSTP1 polymorphisms and lung cancer risk in never-smoking Korean women. 17980933

2008
Entrez Id: 2950
Gene Symbol: GSTP1
GSTP1
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms 		0.600 GeneticVariation LHGDN Combined effect of GSTM1, GSTT1 and GSTP1 polymorphisms on histological subtypes of lung cancer. 18415801

2008
Entrez Id: 2950
Gene Symbol: GSTP1
GSTP1
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms 		0.600 AlteredExpression LHGDN Expression of glutathione S-transferase pi and glutathione synthase correlates with survival in early stage non-small cell carcinomas of the lung. 17234469

2007
Entrez Id: 2950
Gene Symbol: GSTP1
GSTP1
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms 		0.600 GeneticVariation LHGDN Combined effects of genetic polymorphisms in six selected genes on lung cancer susceptibility. 17428572

2007
Entrez Id: 2950
Gene Symbol: GSTP1
GSTP1
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms 		0.600 GeneticVariation LHGDN A literature review of molecular markers predictive of clinical response to cytotoxic chemotherapy in patients with lung cancer. 17409824

2006
Entrez Id: 2950
Gene Symbol: GSTP1
GSTP1
CUI: C0005695
Disease: Bladder Neoplasm
Bladder Neoplasm 		0.600 GeneticVariation LHGDN GSTM1, GSTT1 and GSTP1 genotype frequencies were determined in bladder cancer cases (n=72) and healthy controls with no history of malignancies (n=82) using PCR-based techniques. 15832776

2005
Entrez Id: 2950
Gene Symbol: GSTP1
GSTP1
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms 		0.600 AlteredExpression LHGDN Identification of postoperative adjuvant chemotherapy responders in non-small cell lung cancer by novel biomarker. 15900595

2005
Entrez Id: 2950
Gene Symbol: GSTP1
GSTP1
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms 		0.600 GeneticVariation LHGDN Glutathione S-transferase M1 and P1 metabolic polymorphism and lung cancer predisposition. 14628089

2003
Entrez Id: 2950
Gene Symbol: GSTP1
GSTP1
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms 		0.600 Biomarker LHGDN Smoking and the risk of lung cancer: susceptibility with GSTP1 polymorphisms. 14501269

2003
Entrez Id: 2950
Gene Symbol: GSTP1
GSTP1
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms 		0.600 AlteredExpression LHGDN Transcripts in pretreatment biopsies from a three-arm randomized trial in metastatic non-small-cell lung cancer. 12789263

2003
Entrez Id: 2950
Gene Symbol: GSTP1
GSTP1
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms 		0.600 GeneticVariation LHGDN Genetic polymorphisms of glutathione S-transferases as modulators of lung cancer susceptibility. 12189190

2002
Entrez Id: 2950
Gene Symbol: GSTP1
GSTP1
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms 		0.600 Biomarker LHGDN Genetic determinants of lung cancer short-term survival: the role of glutathione-related genes. 11844594

2002
Entrez Id: 2950
Gene Symbol: GSTP1
GSTP1
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms 		0.600 GeneticVariation LHGDN Associations between carcinogen-DNA damage, glutathione S-transferase genotypes, and risk of lung cancer in the prospective Physicians' Health Cohort Study. 12376472

2002
Entrez Id: 2950
Gene Symbol: GSTP1
GSTP1
CUI: C0004096
Disease: Asthma
Asthma 		0.400 GeneticVariation LHGDN GSTM1 null was independently associated with an increased risk of asthma and showed little variation with air pollution or GSTP1 genotype. 18988661

2009
Entrez Id: 2950
Gene Symbol: GSTP1
GSTP1
CUI: C0004096
Disease: Asthma
Asthma 		0.400 GeneticVariation LHGDN The associations of GSTP1 variants with asthma and wheezing were assessed among white children in the Children's Health Study (CHS). 18335111

2008
Entrez Id: 2950
Gene Symbol: GSTP1
GSTP1
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms 		0.400 Biomarker LHGDN Glutathione S-transferase Pi mediates proliferation of androgen-independent prostate cancer cells. 18413363

2008
Entrez Id: 2950
Gene Symbol: GSTP1
GSTP1
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms 		0.400 PosttranslationalModification LHGDN Promoter hypermethylation in circulating blood cells identifies prostate cancer progression. 17960617

2008
Entrez Id: 2950
Gene Symbol: GSTP1
GSTP1
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.400 GeneticVariation LHGDN Relation of glutathione S-transferase T1, M1 and P1 genotypes and breast cancer risk. 18521819

2008
Entrez Id: 2950
Gene Symbol: GSTP1
GSTP1
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.400 Biomarker LHGDN Role of GSTM1 (Null/Present), GSTP1 (Ile105Val) and P53 (Arg72Pro) genetic polymorphisms and the risk of breast cancer: a case control study from South India. 17696741

2008
Entrez Id: 2950
Gene Symbol: GSTP1
GSTP1
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.400 GeneticVariation LHGDN Multiple Genetic Polymorphisms of GSTP1 313AG, MDR1 3435CC, and MTHFR 677CC highly correlated with early relapse of breast cancer patients in Taiwan. 18095031

2008
Entrez Id: 2950
Gene Symbol: GSTP1
GSTP1
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.400 GeneticVariation LHGDN Glutathione S-transferase M1 and P1 polymorphisms and risk of breast cancer and fibrocystic breast conditions in Chinese women. 17624589

2008
Entrez Id: 2950
Gene Symbol: GSTP1
GSTP1
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.400 GeneticVariation LHGDN Polymorphisms in manganese superoxide dismutase, myeloperoxidase and glutathione-S-transferase and survival after treatment for metastatic breast cancer. 17922231

2008
Entrez Id: 2950
Gene Symbol: GSTP1
GSTP1
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.400 GeneticVariation LHGDN Cruciferous vegetables, the GSTP1 Ile105Val genetic polymorphism, and breast cancer risk. 18326615

2008