Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7124
Gene Symbol: TNF
TNF
tumor necrosis factor 0.231 0.962 0.80
CUI: C0598608
Disease: Hyperhomocysteinemia
Hyperhomocysteinemia
disease 0.340 None 1.000 4 1 2003 2019
Entrez Id: 3569
Gene Symbol: IL6
IL6
interleukin 6 0.248 0.962 0.32
CUI: C0598608
Disease: Hyperhomocysteinemia
Hyperhomocysteinemia
disease 0.030 None 1.000 3 0 2012 2019
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
vascular endothelial growth factor A 0.266 0.923 2.4E-05
CUI: C0598608
Disease: Hyperhomocysteinemia
Hyperhomocysteinemia
disease 0.020 None 1.000 1 0 2003 2014
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
interleukin 1 beta 0.276 0.962 0.13
CUI: C0598608
Disease: Hyperhomocysteinemia
Hyperhomocysteinemia
disease 0.030 None 1.000 3 0 2017 2020
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
transforming growth factor beta 1 0.287 0.962 3.7E-02
CUI: C0598608
Disease: Hyperhomocysteinemia
Hyperhomocysteinemia
disease 0.020 None 1.000 2 0 2006 2019
Entrez Id: 3458
Gene Symbol: IFNG
IFNG
interferon gamma 0.288 0.962 0.47
CUI: C0598608
Disease: Hyperhomocysteinemia
Hyperhomocysteinemia
disease 0.010 None 1.000 1 0 2019 2019
Entrez Id: 596
Gene Symbol: BCL2
BCL2
BCL2 apoptosis regulator 0.291 0.885 0.56
CUI: C0598608
Disease: Hyperhomocysteinemia
Hyperhomocysteinemia
disease 0.010 None 1.000 1 0 2019 2019
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha 0.292 0.923 1.00
CUI: C0598608
Disease: Hyperhomocysteinemia
Hyperhomocysteinemia
disease 0.010 None 1.000 1 0 2018 2018
Entrez Id: 1401
Gene Symbol: CRP
CRP
C-reactive protein 0.299 0.962 3.7E-03
CUI: C0598608
Disease: Hyperhomocysteinemia
Hyperhomocysteinemia
disease 0.030 None 1.000 3 0 2006 2019
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
matrix metallopeptidase 9 0.305 0.923 1.9E-17
CUI: C0598608
Disease: Hyperhomocysteinemia
Hyperhomocysteinemia
disease 0.040 None 1.000 4 0 2001 2019
Entrez Id: 207
Gene Symbol: AKT1
AKT1
AKT serine/threonine kinase 1 0.311 0.962 0.98
CUI: C0598608
Disease: Hyperhomocysteinemia
Hyperhomocysteinemia
disease 0.010 None 1.000 1 0 2018 2018
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
prostaglandin-endoperoxide synthase 2 0.314 0.962 1.00
CUI: C0598608
Disease: Hyperhomocysteinemia
Hyperhomocysteinemia
disease 0.010 None 1.000 1 0 2018 2018
Entrez Id: 5293
Gene Symbol: PIK3CD
PIK3CD
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta 0.319 0.885 1.00
CUI: C0598608
Disease: Hyperhomocysteinemia
Hyperhomocysteinemia
disease 0.010 None 1.000 1 0 2018 2018
Entrez Id: 5294
Gene Symbol: PIK3CG
PIK3CG
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma 0.320 0.885 1.4E-06
CUI: C0598608
Disease: Hyperhomocysteinemia
Hyperhomocysteinemia
disease 0.010 None 1.000 1 0 2018 2018
Entrez Id: 6347
Gene Symbol: CCL2
CCL2
C-C motif chemokine ligand 2 0.321 0.962 0.61
CUI: C0598608
Disease: Hyperhomocysteinemia
Hyperhomocysteinemia
disease 0.270 None 1.000 7 0 2006 2019
Entrez Id: 7099
Gene Symbol: TLR4
TLR4
toll like receptor 4 0.321 0.962 4.6E-09
CUI: C0598608
Disease: Hyperhomocysteinemia
Hyperhomocysteinemia
disease 0.040 None 1.000 4 0 2017 2019
Entrez Id: 5291
Gene Symbol: PIK3CB
PIK3CB
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta 0.322 0.885 1.00
CUI: C0598608
Disease: Hyperhomocysteinemia
Hyperhomocysteinemia
disease 0.010 None 1.000 1 0 2018 2018
Entrez Id: 3605
Gene Symbol: IL17A
IL17A
interleukin 17A 0.324 0.923 4.3E-02
CUI: C0598608
Disease: Hyperhomocysteinemia
Hyperhomocysteinemia
disease 0.010 None 1.000 1 0 2018 2018
Entrez Id: 60
Gene Symbol: ACTB
ACTB
actin beta 0.325 0.923 0.99
CUI: C0598608
Disease: Hyperhomocysteinemia
Hyperhomocysteinemia
disease 0.010 None 1.000 1 0 2019 2019
Entrez Id: 1636
Gene Symbol: ACE
ACE
angiotensin I converting enzyme 0.328 0.923 1.0E-37
CUI: C0598608
Disease: Hyperhomocysteinemia
Hyperhomocysteinemia
disease 0.030 None 1.000 2 0 2000 2017
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
erb-b2 receptor tyrosine kinase 2 0.328 0.923 6.0E-03
CUI: C0598608
Disease: Hyperhomocysteinemia
Hyperhomocysteinemia
disease 0.010 None 1.000 1 0 2013 2013
Entrez Id: 4313
Gene Symbol: MMP2
MMP2
matrix metallopeptidase 2 0.333 0.923 0.84
CUI: C0598608
Disease: Hyperhomocysteinemia
Hyperhomocysteinemia
disease 0.030 None 1.000 3 0 2006 2019
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR
methylenetetrahydrofolate reductase 0.337 0.885 3.2E-10
CUI: C0598608
Disease: Hyperhomocysteinemia
Hyperhomocysteinemia
disease 0.400 None 0.927 259 6 1995 2019
Entrez Id: 348
Gene Symbol: APOE
APOE
apolipoprotein E 0.338 0.962 1.9E-03
CUI: C0598608
Disease: Hyperhomocysteinemia
Hyperhomocysteinemia
disease 0.300 None 0.929 13 0 2004 2018
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
ATP binding cassette subfamily B member 1 0.344 0.885 1.3E-05
CUI: C0598608
Disease: Hyperhomocysteinemia
Hyperhomocysteinemia
disease 0.010 None 1.000 1 1 2013 2013