Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR
methylenetetrahydrofolate reductase 0.337 0.885 3.2E-10
CUI: C0598608
Disease: Hyperhomocysteinemia
Hyperhomocysteinemia
disease 0.400 None 0.927 259 6 1995 2019
Entrez Id: 875
Gene Symbol: CBS
CBS
cystathionine beta-synthase 0.465 0.885 3.1E-05
CUI: C0598608
Disease: Hyperhomocysteinemia
Hyperhomocysteinemia
disease 0.600 None 0.941 46 5 1995 2019
Entrez Id: 102724560
Gene Symbol: CBSL
CBSL
cystathionine beta-synthase like 0.540 0.808
CUI: C0598608
Disease: Hyperhomocysteinemia
Hyperhomocysteinemia
disease 0.100 None 0.971 35 0 1995 2019
Entrez Id: 2153
Gene Symbol: F5
F5
coagulation factor V 0.441 0.846 5.9E-15
CUI: C0598608
Disease: Hyperhomocysteinemia
Hyperhomocysteinemia
disease 0.100 None 0.960 24 1 1998 2017
Entrez Id: 2147
Gene Symbol: F2
F2
coagulation factor II, thrombin 0.415 0.885 1.1E-03
CUI: C0598608
Disease: Hyperhomocysteinemia
Hyperhomocysteinemia
disease 0.300 None 1.000 15 2 1997 2016
Entrez Id: 348
Gene Symbol: APOE
APOE
apolipoprotein E 0.338 0.962 1.9E-03
CUI: C0598608
Disease: Hyperhomocysteinemia
Hyperhomocysteinemia
disease 0.300 None 0.929 13 0 2004 2018
Entrez Id: 4548
Gene Symbol: MTR
MTR
5-methyltetrahydrofolate-homocysteine methyltransferase 0.482 0.808 2.4E-12
CUI: C0598608
Disease: Hyperhomocysteinemia
Hyperhomocysteinemia
disease 0.090 None 1.000 8 2 1996 2019
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
nitric oxide synthase 3 0.378 0.885 6.7E-07
CUI: C0598608
Disease: Hyperhomocysteinemia
Hyperhomocysteinemia
disease 0.080 None 1.000 8 2 2003 2013
Entrez Id: 1351
Gene Symbol: COX8A
COX8A
cytochrome c oxidase subunit 8A 0.400 0.846 0.12
CUI: C0598608
Disease: Hyperhomocysteinemia
Hyperhomocysteinemia
disease 0.070 None 1.000 7 0 2001 2019
Entrez Id: 6347
Gene Symbol: CCL2
CCL2
C-C motif chemokine ligand 2 0.321 0.962 0.61
CUI: C0598608
Disease: Hyperhomocysteinemia
Hyperhomocysteinemia
disease 0.270 None 1.000 7 0 2006 2019
Entrez Id: 635
Gene Symbol: BHMT
BHMT
betaine--homocysteine S-methyltransferase 0.595 0.731 3.7E-14
CUI: C0598608
Disease: Hyperhomocysteinemia
Hyperhomocysteinemia
disease 0.070 None 1.000 7 1 2000 2019
Entrez Id: 5444
Gene Symbol: PON1
PON1
paraoxonase 1 0.409 0.885 9.8E-11
CUI: C0598608
Disease: Hyperhomocysteinemia
Hyperhomocysteinemia
disease 0.360 None 1.000 6 1 2006 2018
Entrez Id: 4018
Gene Symbol: LPA
LPA
lipoprotein(a) 0.444 0.769 6.6E-89
CUI: C0598608
Disease: Hyperhomocysteinemia
Hyperhomocysteinemia
disease 0.060 None 1.000 6 0 2001 2016
Entrez Id: 4552
Gene Symbol: MTRR
MTRR
5-methyltetrahydrofolate-homocysteine methyltransferase reductase 0.502 0.808 2.2E-14
CUI: C0598608
Disease: Hyperhomocysteinemia
Hyperhomocysteinemia
disease 0.370 None 1.000 6 2 1999 2018
Entrez Id: 5054
Gene Symbol: SERPINE1
SERPINE1
serpin family E member 1 0.359 0.885 4.4E-02
CUI: C0598608
Disease: Hyperhomocysteinemia
Hyperhomocysteinemia
disease 0.050 None 1.000 5 1 2000 2019
Entrez Id: 7124
Gene Symbol: TNF
TNF
tumor necrosis factor 0.231 0.962 0.80
CUI: C0598608
Disease: Hyperhomocysteinemia
Hyperhomocysteinemia
disease 0.340 None 1.000 4 1 2003 2019
Entrez Id: 114548
Gene Symbol: NLRP3
NLRP3
NLR family pyrin domain containing 3 0.361 0.962 8.1E-04
CUI: C0598608
Disease: Hyperhomocysteinemia
Hyperhomocysteinemia
disease 0.040 None 1.000 4 0 2017 2019
Entrez Id: 4780
Gene Symbol: NFE2L2
NFE2L2
nuclear factor, erythroid 2 like 2 0.357 0.885 3.6E-03
CUI: C0598608
Disease: Hyperhomocysteinemia
Hyperhomocysteinemia
disease 0.040 None 1.000 4 0 2018 2019
Entrez Id: 23411
Gene Symbol: SIRT1
SIRT1
sirtuin 1 0.378 0.885 8.7E-02
CUI: C0598608
Disease: Hyperhomocysteinemia
Hyperhomocysteinemia
disease 0.040 None 1.000 4 0 2015 2020
Entrez Id: 7099
Gene Symbol: TLR4
TLR4
toll like receptor 4 0.321 0.962 4.6E-09
CUI: C0598608
Disease: Hyperhomocysteinemia
Hyperhomocysteinemia
disease 0.040 None 1.000 4 0 2017 2019
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
matrix metallopeptidase 9 0.305 0.923 1.9E-17
CUI: C0598608
Disease: Hyperhomocysteinemia
Hyperhomocysteinemia
disease 0.040 None 1.000 4 0 2001 2019
Entrez Id: 2551
Gene Symbol: GABPA
GABPA
GA binding protein transcription factor subunit alpha 0.379 0.885 1.00
CUI: C0598608
Disease: Hyperhomocysteinemia
Hyperhomocysteinemia
disease 0.030 None 1.000 3 0 2018 2019
Entrez Id: 5315
Gene Symbol: PKM
PKM
pyruvate kinase M1/2 0.482 0.808 0.85
CUI: C0598608
Disease: Hyperhomocysteinemia
Hyperhomocysteinemia
disease 0.030 None 1.000 3 0 2017 2020
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
interleukin 1 beta 0.276 0.962 0.13
CUI: C0598608
Disease: Hyperhomocysteinemia
Hyperhomocysteinemia
disease 0.030 None 1.000 3 0 2017 2020
Entrez Id: 4313
Gene Symbol: MMP2
MMP2
matrix metallopeptidase 2 0.333 0.923 0.84
CUI: C0598608
Disease: Hyperhomocysteinemia
Hyperhomocysteinemia
disease 0.030 None 1.000 3 0 2006 2019