| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
cystathionine beta-synthase | 0.465 | 0.885 | 3.1E-05 |
|
disease | 0.600 | None | 0.941 | 46 | 5 | 1995 | 2019 | ||||||||
|
methylenetetrahydrofolate reductase | 0.337 | 0.885 | 3.2E-10 |
|
disease | 0.400 | None | 0.927 | 259 | 6 | 1995 | 2019 | ||||||||
|
5-methyltetrahydrofolate-homocysteine methyltransferase reductase | 0.502 | 0.808 | 2.2E-14 |
|
disease | 0.370 | None | 1.000 | 6 | 2 | 1999 | 2018 | ||||||||
|
paraoxonase 1 | 0.409 | 0.885 | 9.8E-11 |
|
disease | 0.360 | None | 1.000 | 6 | 1 | 2006 | 2018 | ||||||||
|
tumor necrosis factor | 0.231 | 0.962 | 0.80 |
|
disease | 0.340 | None | 1.000 | 4 | 1 | 2003 | 2019 | ||||||||
|
caspase 1 | 0.413 | 0.885 | 3.5E-05 |
|
disease | 0.310 | None | 1.000 | 1 | 0 | 2012 | 2017 | ||||||||
|
coagulation factor II, thrombin | 0.415 | 0.885 | 1.1E-03 |
|
disease | 0.300 | None | 1.000 | 15 | 2 | 1997 | 2016 | ||||||||
|
apolipoprotein E | 0.338 | 0.962 | 1.9E-03 |
|
disease | 0.300 | None | 0.929 | 13 | 0 | 2004 | 2018 | ||||||||
|
C-C motif chemokine ligand 2 | 0.321 | 0.962 | 0.61 |
|
disease | 0.270 | None | 1.000 | 7 | 0 | 2006 | 2019 | ||||||||
|
adenosylhomocysteinase | 0.582 | 0.692 | 3.6E-02 |
|
disease | 0.220 | None | 1.000 | 2 | 0 | 2002 | 2019 | ||||||||
|
coagulation factor VIII | 0.542 | 0.769 | 1.00 |
|
disease | 0.220 | None | 1.000 | 2 | 0 | 2005 | 2019 | ||||||||
|
glutamate ionotropic receptor NMDA type subunit 2A | 0.522 | 0.808 | 1.00 |
|
disease | 0.210 | None | 1.000 | 1 | 0 | 2015 | 2019 | ||||||||
|
butyrylcholinesterase | 0.447 | 0.923 | 1.1E-13 |
|
disease | 0.210 | None | 1.000 | 1 | 0 | 2006 | 2009 | ||||||||
|
cystathionine beta-synthase like | 0.540 | 0.808 |
|
disease | 0.100 | None | 0.971 | 35 | 0 | 1995 | 2019 | |||||||||
|
coagulation factor V | 0.441 | 0.846 | 5.9E-15 |
|
disease | 0.100 | None | 0.960 | 24 | 1 | 1998 | 2017 | ||||||||
|
5-methyltetrahydrofolate-homocysteine methyltransferase | 0.482 | 0.808 | 2.4E-12 |
|
disease | 0.090 | None | 1.000 | 8 | 2 | 1996 | 2019 | ||||||||
|
nitric oxide synthase 3 | 0.378 | 0.885 | 6.7E-07 |
|
disease | 0.080 | None | 1.000 | 8 | 2 | 2003 | 2013 | ||||||||
|
cytochrome c oxidase subunit 8A | 0.400 | 0.846 | 0.12 |
|
disease | 0.070 | None | 1.000 | 7 | 0 | 2001 | 2019 | ||||||||
|
betaine--homocysteine S-methyltransferase | 0.595 | 0.731 | 3.7E-14 |
|
disease | 0.070 | None | 1.000 | 7 | 1 | 2000 | 2019 | ||||||||
|
lipoprotein(a) | 0.444 | 0.769 | 6.6E-89 |
|
disease | 0.060 | None | 1.000 | 6 | 0 | 2001 | 2016 | ||||||||
|
serpin family E member 1 | 0.359 | 0.885 | 4.4E-02 |
|
disease | 0.050 | None | 1.000 | 5 | 1 | 2000 | 2019 | ||||||||
|
NLR family pyrin domain containing 3 | 0.361 | 0.962 | 8.1E-04 |
|
disease | 0.040 | None | 1.000 | 4 | 0 | 2017 | 2019 | ||||||||
|
nuclear factor, erythroid 2 like 2 | 0.357 | 0.885 | 3.6E-03 |
|
disease | 0.040 | None | 1.000 | 4 | 0 | 2018 | 2019 | ||||||||
|
sirtuin 1 | 0.378 | 0.885 | 8.7E-02 |
|
disease | 0.040 | None | 1.000 | 4 | 0 | 2015 | 2020 | ||||||||
|
toll like receptor 4 | 0.321 | 0.962 | 4.6E-09 |
|
disease | 0.040 | None | 1.000 | 4 | 0 | 2017 | 2019 |