| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
tumor protein p53 | 0.236 | 0.962 | 0.53 |
|
group | 0.700 | None | 0.984 | 257 | 90 | 1982 | 2020 | ||||||||
|
BRCA1 DNA repair associated | 0.367 | 0.923 | 9.2E-29 |
|
group | 0.500 | None | 0.976 | 340 | 62 | 1976 | 2019 | ||||||||
|
BRCA2 DNA repair associated | 0.379 | 0.846 | 2.4E-25 |
|
group | 0.500 | None | 0.987 | 153 | 50 | 1995 | 2019 | ||||||||
|
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | 0.292 | 0.923 | 1.00 |
|
group | 0.500 | None | 0.978 | 89 | 34 | 2004 | 2020 | ||||||||
|
erb-b2 receptor tyrosine kinase 2 | 0.328 | 0.923 | 6.0E-03 |
|
group | 0.500 | None | 0.975 | 677 | 16 | 1987 | 2020 | ||||||||
|
phosphatase and tensin homolog | 0.305 | 0.923 | 0.26 |
|
group | 0.500 | None | 1.000 | 43 | 9 | 1998 | 2019 | ||||||||
|
estrogen receptor 1 | 0.324 | 0.962 | 1.00 |
|
group | 0.500 | None | 0.978 | 551 | 8 | 1988 | 2020 | ||||||||
|
HRas proto-oncogene, GTPase | 0.378 | 0.885 | 8.0E-02 |
|
group | 0.450 | None | 1.000 | 11 | 8 | 1988 | 2016 | ||||||||
|
checkpoint kinase 2 | 0.460 | 0.808 | 1.2E-24 |
|
group | 0.500 | None | 0.964 | 55 | 7 | 2002 | 2017 | ||||||||
|
microRNA 4728 | 0.769 | 0.269 |
|
group | 0.020 | None | 1.000 | 2 | 6 | 2015 | 2018 | |||||||||
|
partner and localizer of BRCA2 | 0.485 | 0.769 | 3.0E-19 |
|
group | 0.500 | None | 1.000 | 15 | 5 | 2006 | 2020 | ||||||||
|
mechanistic target of rapamycin kinase | 0.343 | 0.885 | 1.00 |
|
group | 0.500 | None | 1.000 | 12 | 5 | 2003 | 2019 | ||||||||
|
fibroblast growth factor receptor 2 | 0.380 | 0.808 | 1.00 |
|
group | 0.500 | None | 0.950 | 20 | 4 | 1991 | 2016 | ||||||||
|
F-box and WD repeat domain containing 7 | 0.465 | 0.808 | 1.00 |
|
group | 0.420 | None | 0.667 | 3 | 4 | 2008 | 2016 | ||||||||
|
ATM serine/threonine kinase | 0.374 | 0.885 | 5.6E-47 |
|
group | 0.500 | None | 0.974 | 39 | 3 | 1996 | 2018 | ||||||||
|
erb-b2 receptor tyrosine kinase 3 | 0.448 | 0.808 | 1.7E-15 |
|
group | 0.500 | None | 1.000 | 26 | 3 | 1999 | 2018 | ||||||||
|
ras homolog family member A | 0.502 | 0.808 | 0.60 |
|
group | 0.140 | None | 1.000 | 5 | 3 | 2004 | 2016 | ||||||||
|
HECT and RLD domain containing E3 ubiquitin protein ligase 2 | 0.568 | 0.692 | 1.00 |
|
group | 0.100 | None | 1.000 | 2 | 3 | 2006 | 2013 | ||||||||
|
erb-b2 receptor tyrosine kinase 4 | 0.455 | 0.846 | 1.00 |
|
group | 0.100 | None | 0.882 | 17 | 2 | 1998 | 2018 | ||||||||
|
methylenetetrahydrofolate reductase | 0.337 | 0.885 | 3.2E-10 |
|
group | 0.400 | None | 0.941 | 17 | 2 | 2004 | 2017 | ||||||||
|
mutL homolog 1 | 0.399 | 0.808 | 3.4E-05 |
|
group | 0.070 | None | 1.000 | 7 | 2 | 1999 | 2014 | ||||||||
|
SMAD family member 4 | 0.401 | 0.808 | 1.00 |
|
group | 0.150 | None | 1.000 | 6 | 2 | 1997 | 2016 | ||||||||
|
BRCA1 associated RING domain 1 | 0.597 | 0.538 | 1.4E-24 |
|
group | 0.450 | None | 1.000 | 5 | 2 | 2004 | 2008 | ||||||||
|
exportin 1 | 0.504 | 0.692 | 1.00 |
|
group | 0.120 | None | 1.000 | 3 | 2 | 2016 | 2019 | ||||||||
|
DNA polymerase epsilon, catalytic subunit | 0.526 | 0.731 | 8.0E-27 |
|
group | 0.110 | None | 1.000 | 2 | 2 | 2009 | 2016 |