Source: ANIMAL_MODELS

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 639
Gene Symbol: PRDM1
PRDM1
CUI: C0024141
Disease: Lupus Erythematosus, Systemic
Lupus Erythematosus, Systemic
0.550 Biomarker MGD

Entrez Id: 9474
Gene Symbol: ATG5
ATG5
CUI: C0024141
Disease: Lupus Erythematosus, Systemic
Lupus Erythematosus, Systemic
0.390 Biomarker MGD

Entrez Id: 51284
Gene Symbol: TLR7
TLR7
CUI: C0024141
Disease: Lupus Erythematosus, Systemic
Lupus Erythematosus, Systemic
0.300 Biomarker MGD

Entrez Id: 959
Gene Symbol: CD40LG
CD40LG
CUI: C0024141
Disease: Lupus Erythematosus, Systemic
Lupus Erythematosus, Systemic
0.300 Biomarker MGD

Entrez Id: 5468
Gene Symbol: PPARG
PPARG
CUI: C0024141
Disease: Lupus Erythematosus, Systemic
Lupus Erythematosus, Systemic
0.230 Biomarker MGD

Entrez Id: 3726
Gene Symbol: JUNB
JUNB
CUI: C0024141
Disease: Lupus Erythematosus, Systemic
Lupus Erythematosus, Systemic
0.230 Biomarker MGD

Entrez Id: 8678
Gene Symbol: BECN1
BECN1
CUI: C0024141
Disease: Lupus Erythematosus, Systemic
Lupus Erythematosus, Systemic
0.210 Biomarker MGD

Entrez Id: 3635
Gene Symbol: INPP5D
INPP5D
CUI: C0024141
Disease: Lupus Erythematosus, Systemic
Lupus Erythematosus, Systemic
0.210 Biomarker MGD

Entrez Id: 10533
Gene Symbol: ATG7
ATG7
CUI: C0024141
Disease: Lupus Erythematosus, Systemic
Lupus Erythematosus, Systemic
0.210 Biomarker MGD

Entrez Id: 2033
Gene Symbol: EP300
EP300
CUI: C0024141
Disease: Lupus Erythematosus, Systemic
Lupus Erythematosus, Systemic
0.200 Biomarker MGD

Entrez Id: 6256
Gene Symbol: RXRA
RXRA
CUI: C0024141
Disease: Lupus Erythematosus, Systemic
Lupus Erythematosus, Systemic
0.200 Biomarker MGD

Entrez Id: 355
Gene Symbol: FAS
FAS
CUI: C0024141
Disease: Lupus Erythematosus, Systemic
Lupus Erythematosus, Systemic
0.400 Biomarker MGD Spontaneous murine lupus-like syndromes. Clinical and immunopathological manifestations in several strains. 309911

1978

Entrez Id: 355
Gene Symbol: FAS
FAS
CUI: C0024141
Disease: Lupus Erythematosus, Systemic
Lupus Erythematosus, Systemic
0.400 Biomarker MGD Distribution of lymphocytes identified by surface markers in murine strains with systemic lupus erythematosus-like syndromes. 762500

1979

Entrez Id: 355
Gene Symbol: FAS
FAS
CUI: C0024141
Disease: Lupus Erythematosus, Systemic
Lupus Erythematosus, Systemic
0.400 Biomarker MGD Splenic immunoglobulin-secreting cells and their regulation in autoimmune mice. 6444324

1980

Entrez Id: 355
Gene Symbol: FAS
FAS
CUI: C0024141
Disease: Lupus Erythematosus, Systemic
Lupus Erythematosus, Systemic
0.400 Biomarker MGD Deficient interleukin 2 activity in MRL/Mp and C57BL/6J mice bearing the lpr gene. 6975351

1981

Entrez Id: 355
Gene Symbol: FAS
FAS
CUI: C0024141
Disease: Lupus Erythematosus, Systemic
Lupus Erythematosus, Systemic
0.400 Biomarker MGD Dissociation of severe lupus-like disease from polyclonal B cell activation and IL 2 deficiency in C3H-lpr/lpr mice. 6610701

1984

Entrez Id: 355
Gene Symbol: FAS
FAS
CUI: C0024141
Disease: Lupus Erythematosus, Systemic
Lupus Erythematosus, Systemic
0.400 Biomarker MGD Phenotypic, functional, and molecular genetic comparisons of the abnormal lymphoid cells of C3H-lpr/lpr and C3H-gld/gld mice. 3009614

1986

Entrez Id: 355
Gene Symbol: FAS
FAS
CUI: C0024141
Disease: Lupus Erythematosus, Systemic
Lupus Erythematosus, Systemic
0.400 Biomarker MGD Comparative influence of steroid hormones and immunosuppressive agents on autoimmune expression in lacrimal glands of a female mouse model of Sjögren's syndrome. 8163351

1994

Entrez Id: 355
Gene Symbol: FAS
FAS
CUI: C0024141
Disease: Lupus Erythematosus, Systemic
Lupus Erythematosus, Systemic
0.400 Biomarker MGD Transfer of Sjögren's syndrome-like autoimmune lesions into SCID mice and prevention of lesions by anti-CD4 and anti-T cell receptor antibody treatment. 7957574

1994

Entrez Id: 355
Gene Symbol: FAS
FAS
CUI: C0024141
Disease: Lupus Erythematosus, Systemic
Lupus Erythematosus, Systemic
0.400 Biomarker MGD Reduced cell-cell communication in a spontaneous murine model of autoimmune thyroid disease. 7628400

1995

Entrez Id: 4124
Gene Symbol: MAN2A1
MAN2A1
CUI: C0024141
Disease: Lupus Erythematosus, Systemic
Lupus Erythematosus, Systemic
0.210 Biomarker MGD Alpha-mannosidase-II deficiency results in dyserythropoiesis and unveils an alternate pathway in oligosaccharide biosynthesis. 9230311

1997

Entrez Id: 5133
Gene Symbol: PDCD1
PDCD1
CUI: C0024141
Disease: Lupus Erythematosus, Systemic
Lupus Erythematosus, Systemic
0.800 Biomarker MGD Immunological studies on PD-1 deficient mice: implication of PD-1 as a negative regulator for B cell responses. 9796923

1998

Entrez Id: 712
Gene Symbol: C1QA
C1QA
CUI: C0024141
Disease: Lupus Erythematosus, Systemic
Lupus Erythematosus, Systemic
0.670 Biomarker MGD Homozygous C1q deficiency causes glomerulonephritis associated with multiple apoptotic bodies. 9590289

1998

Entrez Id: 22806
Gene Symbol: IKZF3
IKZF3
CUI: C0024141
Disease: Lupus Erythematosus, Systemic
Lupus Erythematosus, Systemic
0.330 Biomarker MGD Aiolos regulates B cell activation and maturation to effector state. 9806640

1998

Entrez Id: 5133
Gene Symbol: PDCD1
PDCD1
CUI: C0024141
Disease: Lupus Erythematosus, Systemic
Lupus Erythematosus, Systemic
0.800 Biomarker MGD Development of lupus-like autoimmune diseases by disruption of the PD-1 gene encoding an ITIM motif-carrying immunoreceptor. 10485649

1999