Source: ANIMAL_MODELS

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5905
Gene Symbol: RANGAP1
RANGAP1
CUI: C0149940
Disease: Sciatic Neuropathy
Sciatic Neuropathy
0.200 Biomarker RGD Localized regulation of axonal RanGTPase controls retrograde injury signaling in peripheral nerve. 18667152

2008

Entrez Id: 8911
Gene Symbol: CACNA1I
CACNA1I
CUI: C0149940
Disease: Sciatic Neuropathy
Sciatic Neuropathy
0.200 Biomarker RGD Upregulation of T-type Ca2+ channels in primary sensory neurons in spinal nerve injury. 22972512

2013

Entrez Id: 5159
Gene Symbol: PDGFRB
PDGFRB
CUI: C0149940
Disease: Sciatic Neuropathy
Sciatic Neuropathy
0.200 Biomarker RGD Activation of MAP kinases, Akt and PDGF receptors in injured peripheral nerves. 19909480

2009

Entrez Id: 3735
Gene Symbol: KARS1
KARS1
CUI: C0149940
Disease: Sciatic Neuropathy
Sciatic Neuropathy
0.200 Biomarker RGD Expression profile of aminoacyl-tRNA synthetases in dorsal root ganglion neurons after peripheral nerve injury. 25467976

2015

Entrez Id: 4741
Gene Symbol: NEFM
NEFM
CUI: C0149940
Disease: Sciatic Neuropathy
Sciatic Neuropathy
0.200 Therapeutic RGD Thyroid hormones stimulate expression and modification of cytoskeletal protein during rat sciatic nerve regeneration. 12445968

2002

Entrez Id: 5054
Gene Symbol: SERPINE1
SERPINE1
CUI: C0149940
Disease: Sciatic Neuropathy
Sciatic Neuropathy
0.200 Therapeutic RGD Chinese tuina downregulates the elevated levels of tissue plasminogen activator in sciatic nerve injured Sprague-Dawley rats. 25967608

2017

Entrez Id: 3084
Gene Symbol: NRG1
NRG1
CUI: C0149940
Disease: Sciatic Neuropathy
Sciatic Neuropathy
0.200 Therapeutic RGD Secretion of EGF-like domain of heregulinβ promotes axonal growth and functional recovery of injured sciatic nerve. 20957456

2010

Entrez Id: 56963
Gene Symbol: RGMA
RGMA
CUI: C0149940
Disease: Sciatic Neuropathy
Sciatic Neuropathy
0.200 Biomarker RGD Induction of repulsive guidance molecule in neurons following sciatic nerve injury. 16863689

2006

Entrez Id: 2902
Gene Symbol: GRIN1
GRIN1
CUI: C0149940
Disease: Sciatic Neuropathy
Sciatic Neuropathy
0.200 Biomarker RGD Hippocampal NMDAR-Wnt-Catenin signaling disrupted with cognitive deficits in adolescent offspring exposed to prenatal hypoxia. 26656067

2016

Entrez Id: 5376
Gene Symbol: PMP22
PMP22
CUI: C0149940
Disease: Sciatic Neuropathy
Sciatic Neuropathy
0.200 Biomarker RGD Characterization of a novel peripheral nervous system myelin protein (PMP-22/SR13). 1556154

1992

Entrez Id: 3749
Gene Symbol: KCNC4
KCNC4
CUI: C0149940
Disease: Sciatic Neuropathy
Sciatic Neuropathy
0.200 Biomarker RGD Reduced expression of A-type potassium channels in primary sensory neurons induces mechanical hypersensitivity. 17855600

2007

Entrez Id: 1996
Gene Symbol: ELAVL4
ELAVL4
CUI: C0149940
Disease: Sciatic Neuropathy
Sciatic Neuropathy
0.200 Biomarker RGD Increased expression and localization of the RNA-binding protein HuD and GAP-43 mRNA to cytoplasmic granules in DRG neurons during nerve regeneration. 12957493

2003

Entrez Id: 5156
Gene Symbol: PDGFRA
PDGFRA
CUI: C0149940
Disease: Sciatic Neuropathy
Sciatic Neuropathy
0.200 Biomarker RGD Activation of MAP kinases, Akt and PDGF receptors in injured peripheral nerves. 19909480

2009

Entrez Id: 4035
Gene Symbol: LRP1
LRP1
CUI: C0149940
Disease: Sciatic Neuropathy
Sciatic Neuropathy
0.200 Biomarker RGD Hippocampal NMDAR-Wnt-Catenin signaling disrupted with cognitive deficits in adolescent offspring exposed to prenatal hypoxia. 26656067

2016

Entrez Id: 840
Gene Symbol: CASP7
CASP7
CUI: C0149940
Disease: Sciatic Neuropathy
Sciatic Neuropathy
0.200 Biomarker RGD Evaluation of apoptotic pathways in dorsal root ganglion neurons following peripheral nerve injury. 29659443

2018

Entrez Id: 83700
Gene Symbol: JAM3
JAM3
CUI: C0149940
Disease: Sciatic Neuropathy
Sciatic Neuropathy
0.200 Biomarker RGD The spatiotemporal localization of JAM-C following sciatic nerve crush in adult rats. 22950044

2012

Entrez Id: 1627
Gene Symbol: DBN1
DBN1
CUI: C0149940
Disease: Sciatic Neuropathy
Sciatic Neuropathy
0.200 Biomarker RGD Drebrin expression is increased in spinal motoneurons of rats after axotomy. 11578820

2001

Entrez Id: 6647
Gene Symbol: SOD1
SOD1
CUI: C0149940
Disease: Sciatic Neuropathy
Sciatic Neuropathy
0.200 Therapeutic RGD Superoxide dismutase isoforms 1 and 2 in lumbar spinal cord of neonatal rats after sciatic nerve transection and melatonin treatment. 15707675

2005

Entrez Id: 824
Gene Symbol: CAPN2
CAPN2
CUI: C0149940
Disease: Sciatic Neuropathy
Sciatic Neuropathy
0.200 Biomarker RGD Influence of electrical stimulation on calpain and ubiquitin-proteasome systems in the denervated and unloaded rat tibialis anterior muscles. 24745757

2014

Entrez Id: 3921
Gene Symbol: RPSA
RPSA
CUI: C0149940
Disease: Sciatic Neuropathy
Sciatic Neuropathy
0.200 Biomarker RGD Upregulation in rat spinal cord microglia of the nonintegrin laminin receptor 37 kDa-LRP following activation by a traumatic lesion or peripheral injury. 19196078

2009

Entrez Id: 7133
Gene Symbol: TNFRSF1B
TNFRSF1B
CUI: C0149940
Disease: Sciatic Neuropathy
Sciatic Neuropathy
0.200 Biomarker RGD Axonal transport of TNF-alpha in painful neuropathy: distribution of ligand tracer and TNF receptors. 11240015

2001

Entrez Id: 1269
Gene Symbol: CNR2
CNR2
CUI: C0149940
Disease: Sciatic Neuropathy
Sciatic Neuropathy
0.200 Therapeutic RGD Depression-like behaviour in rats with mononeuropathy is reduced by the CB2-selective agonist GW405833. 19345493

2009

Entrez Id: 1027
Gene Symbol: CDKN1B
CDKN1B
CUI: C0149940
Disease: Sciatic Neuropathy
Sciatic Neuropathy
0.200 Biomarker RGD Dynamic changes of PIRH2 and p27kip1 expression in injured rat sciatic nerve. 21959983

2012

Entrez Id: 5111
Gene Symbol: PCNA
PCNA
CUI: C0149940
Disease: Sciatic Neuropathy
Sciatic Neuropathy
0.200 Biomarker RGD Changes in CLIP3 expression after sciatic nerve injury in adult rats. 23014974

2012

Entrez Id: 57030
Gene Symbol: SLC17A7
SLC17A7
CUI: C0149940
Disease: Sciatic Neuropathy
Sciatic Neuropathy
0.200 Biomarker RGD Differential effects of natural rewards and pain on vesicular glutamate transporter expression in the nucleus accumbens. 23835161

2013