Source: RGD

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 8678
Gene Symbol: BECN1
BECN1
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia
0.210 Biomarker RGD RNA interference-mediated downregulation of Beclin1 attenuates cerebral ischemic injury in rats. 19574998

2009

Entrez Id: 6387
Gene Symbol: CXCL12
CXCL12
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia
0.210 Biomarker RGD SDF-1alpha/CXCR4-mediated migration of systemically transplanted bone marrow stromal cells towards ischemic brain lesion in a rat model. 18206136

2008

Entrez Id: 5578
Gene Symbol: PRKCA
PRKCA
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia
0.210 Biomarker RGD Subtype activation and interaction of protein kinase C and mitogen-activated protein kinase controlling receptor expression in cerebral arteries and microvessels after subarachnoid hemorrhage. 18032736

2008

Entrez Id: 8678
Gene Symbol: BECN1
BECN1
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia
0.210 Biomarker RGD Focal cerebral ischemia induces upregulation of Beclin 1 and autophagy-like cell death. 17936001

2008

Entrez Id: 4842
Gene Symbol: NOS1
NOS1
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia
0.210 Biomarker RGD Early and sharp nitric oxide production and anoxic depolarization in the rat hippocampus during transient forebrain ischemia. 17451676

2007

Entrez Id: 285
Gene Symbol: ANGPT2
ANGPT2
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia
0.210 Biomarker RGD The effect of recombinant human erythropoietin on neurovasculature repair after focal ischemic stroke in neonatal rats. 17494864

2007

Entrez Id: 6547
Gene Symbol: SLC8A3
SLC8A3
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia
0.210 Biomarker RGD Permanent focal brain ischemia induces isoform-dependent changes in the pattern of Na+/Ca2+ exchanger gene expression in the ischemic core, periinfarct area, and intact brain regions. 16107787

2006

Entrez Id: 6543
Gene Symbol: SLC8A2
SLC8A2
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia
0.210 Biomarker RGD Permanent focal brain ischemia induces isoform-dependent changes in the pattern of Na+/Ca2+ exchanger gene expression in the ischemic core, periinfarct area, and intact brain regions. 16107787

2006

Entrez Id: 596
Gene Symbol: BCL2
BCL2
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia
0.210 Therapeutic RGD Lentiviral-mediated delivery of Bcl-2 or GDNF protects against excitotoxicity in the rat hippocampus. 15585409

2005

Entrez Id: 54207
Gene Symbol: KCNK10
KCNK10
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia
0.210 Biomarker RGD Enhanced expressions of arachidonic acid-sensitive tandem-pore domain potassium channels in rat experimental acute cerebral ischemia. 15652517

2005

Entrez Id: 6529
Gene Symbol: SLC6A1
SLC6A1
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia
0.210 Biomarker RGD Sequential release of GABA by exocytosis and reversed uptake leads to neuronal swelling in simulated ischemia of hippocampal slices. 15084665

2004

Entrez Id: 3776
Gene Symbol: KCNK2
KCNK2
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia
0.210 Biomarker RGD Alterations in the expression of lipid and mechano-gated two-pore domain potassium channel genes in rat brain following chronic cerebral ischemia. 14741413

2004

Entrez Id: 7276
Gene Symbol: TTR
TTR
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia
0.210 Biomarker RGD Combined proteomic approach with SELDI-TOF-MS and peptide mass fingerprinting identified the rapid increase of monomeric transthyretin in rat cerebrospinal fluid after transient focal cerebral ischemia. 15469881

2004

Entrez Id: 718
Gene Symbol: C3
C3
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia
0.210 Biomarker RGD Complement activation contributes to hypoxic-ischemic brain injury in neonatal rats. 14561876

2003

Entrez Id: 1020
Gene Symbol: CDK5
CDK5
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia
0.210 Biomarker RGD Cdk5 activation induces hippocampal CA1 cell death by directly phosphorylating NMDA receptors. 14502288

2003

Entrez Id: 1191
Gene Symbol: CLU
CLU
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia
0.210 Biomarker RGD Delayed, but prolonged increases in astrocytic clusterin (ApoJ) mRNA expression following acute cortical spreading depression in the rat: evidence for a role of clusterin in ischemic tolerance. 12782389

2003

Entrez Id: 2100
Gene Symbol: ESR2
ESR2
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia
0.210 Biomarker RGD Estradiol modulates bcl-2 in cerebral ischemia: a potential role for estrogen receptors. 10414967

1999

Entrez Id: 1234
Gene Symbol: CCR5
CCR5
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia
0.210 Biomarker RGD Cloning of rat HIV-1-chemokine coreceptor CKR5 from microglia and upregulation of its mRNA in ischemic and endotoxinemic rat brain. 9670989

1998

Entrez Id: 598
Gene Symbol: BCL2L1
BCL2L1
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia
0.200 Biomarker RGD Cluster analysis of mRNA expression levels identifies multiple sequential patterns following focal cerebral ischemia. 22843461

2012

Entrez Id: 2243
Gene Symbol: FGA
FGA
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia
0.200 Therapeutic RGD [Protective effects and anticoagulation effect of polysaccharides from the sea cucumber on acute incomplete cerebral ischemia in rats]. 22737923

2012

Entrez Id: 572
Gene Symbol: BAD
BAD
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia
0.200 Biomarker RGD Cluster analysis of mRNA expression levels identifies multiple sequential patterns following focal cerebral ischemia. 22843461

2012

Entrez Id: 4133
Gene Symbol: MAP2
MAP2
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia
0.200 Biomarker RGD Microtubule-associated protein 2, an early blood marker of ischemic brain injury. 21948028

2012

Entrez Id: 3654
Gene Symbol: IRAK1
IRAK1
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia
0.200 Biomarker RGD Interleukin-1 receptor associated kinases-1/4 inhibition protects against acute hypoxia/ischemia-induced neuronal injury in vivo and in vitro. 21925238

2011

Entrez Id: 9590
Gene Symbol: AKAP12
AKAP12
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia
0.200 Biomarker RGD Temporal profile of Src, SSeCKS, and angiogenic factors after focal cerebral ischemia: correlations with angiogenesis and cerebral edema. 21334414

2011

Entrez Id: 3162
Gene Symbol: HMOX1
HMOX1
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia
0.200 Biomarker RGD Tin chloride enhances parvalbumin-positive interneuron survival by modulating heme metabolism in a model of cerebral ischemia. 21276833

2011