Source: LHGDN

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms 		0.500 GeneticVariation LHGDN Molecular detection of TP53, Ki-Ras and p16INK4A promoter methylation in plasma of patients with colorectal cancer and its association with prognosis. Results of a 3-year GOIM (Gruppo Oncologico dell'Italia Meridionale) prospective study. 16760301

2006
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms 		0.500 GeneticVariation LHGDN Frequent involvement of ras-signalling pathways in both polypoid-type and flat-type early-stage colorectal cancers. 16918136

2006
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms 		0.500 Biomarker LHGDN Transcriptional targets of hepatocyte growth factor signaling and Ki-ras oncogene activation in colorectal cancer. 16158056

2006
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms 		0.500 GeneticVariation LHGDN Approximately 50% of colorectal tumors contain K-ras gene mutations, which occur as an early step in carcinogenesis. 15514939

2005
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms 		0.500 GeneticVariation LHGDN Dual effect of Kras(D12) knockdown on tumorigenesis: increased immune-mediated tumor clearance and abrogation of tumor malignancy. 16091732

2005
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms 		0.500 GeneticVariation LHGDN APC, K-ras, and p53 gene mutations in colorectal cancer patients: correlation to clinicopathologic features and postoperative surveillance. 15943410

2005
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms 		0.500 GeneticVariation LHGDN Specific TP53 and/or Ki-ras mutations as independent predictors of clinical outcome in sporadic colorectal adenocarcinomas: results of a 5-year Gruppo Oncologico dell'Italia Meridionale (GOIM) prospective study. 15923430

2005
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms 		0.500 GeneticVariation LHGDN Prognostic and predictive factors in colorectal cancer: Kirsten Ras in CRC (RASCAL) and TP53CRC collaborative studies. 15923428

2005
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms 		0.500 GeneticVariation LHGDN Mutant KRAS, chromosomal instability and prognosis in colorectal cancer. 16112461

2005
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms 		0.500 GeneticVariation LHGDN Detection of a K-ras mutation in urine of patients with colorectal cancer. 17192038

2005
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms 		0.500 PosttranslationalModification LHGDN BRAF and KRAS Mutations in hyperplastic polyps and serrated adenomas of the colorectum: relationship to histology and CpG island methylation status. 15489648

2004
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms 		0.500 GeneticVariation LHGDN Peptide nucleic acid clamp PCR: a novel K-ras mutation detection assay for colorectal cancer micrometastases in lymph nodes. 15221969

2004
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms 		0.500 GeneticVariation LHGDN The aim of this work was to study the prevalence of mutations at codons 12, 13 and 61 of the Ki-ras gene in 37 colorectal tumors from Mexican patients and to correlate them with clinical data. 12908779

2003
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms 		0.500 Biomarker LHGDN Specific T-cell immunity against Ki-ras peptides in patients with pancreatic and colorectal cancers. 12592366

2003
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms 		0.500 GeneticVariation LHGDN K-ras mutations and RASSF1A promoter methylation in colorectal cancer. 12032847

2002
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms 		0.500 GeneticVariation LHGDN Mutations in APC, Kirsten-ras, and p53--alternative genetic pathways to colorectal cancer. 12093899

2002