| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
mutS homolog 6 | 0.462 | 0.731 | 3.7E-05 |
|
group | 0.110 | None | 1.000 | 190 | 331 | 1994 | 2018 | ||||||||
|
nibrin | 0.467 | 0.808 | 2.2E-16 |
|
group | 0.100 | None | 1.000 | 36 | 92 | 1998 | 2017 | ||||||||
|
succinate dehydrogenase complex subunit D | 0.472 | 0.885 | 0.34 |
|
group | 0.100 | None | 1.000 | 72 | 31 | 1998 | 2016 | ||||||||
|
succinate dehydrogenase complex iron sulfur subunit B | 0.474 | 0.846 | 2.4E-04 |
|
group | 0.110 | None | 1.000 | 126 | 71 | 1995 | 2018 | ||||||||
|
PMS1 homolog 2, mismatch repair system component | 0.484 | 0.808 | 4.5E-27 |
|
group | 0.110 | None | 1.000 | 112 | 124 | 1995 | 2018 | ||||||||
|
partner and localizer of BRCA2 | 0.485 | 0.769 | 3.0E-19 |
|
group | 0.100 | None | 1.000 | 110 | 293 | 2007 | 2017 | ||||||||
|
fumarate hydratase | 0.489 | 0.846 | 8.8E-02 |
|
group | 0.150 | None | 1.000 | 70 | 63 | 1997 | 2019 | ||||||||
|
CDKN2B antisense RNA 1 | 0.491 | 0.769 |
|
group | 0.100 | None | 0 | 1 | ||||||||||||
|
melanocyte inducing transcription factor | 0.499 | 0.808 | 0.98 |
|
group | 0.100 | None | 1.000 | 22 | 1 | 1987 | 2016 | ||||||||
|
BRCA1 interacting protein C-terminal helicase 1 | 0.507 | 0.731 | 6.2E-17 |
|
group | 0.100 | None | 1.000 | 56 | 145 | 2004 | 2017 | ||||||||
|
FA complementation group C | 0.507 | 0.808 | 2.8E-13 |
|
group | 0.100 | None | 1.000 | 23 | 6 | 1993 | 2017 | ||||||||
|
DNA polymerase delta 1, catalytic subunit | 0.507 | 0.769 | 2.4E-06 |
|
group | 0.100 | None | 1.000 | 7 | 2 | 2006 | 2017 | ||||||||
|
X-ray repair cross complementing 2 | 0.512 | 0.731 | 4.0E-07 |
|
group | 0.100 | None | 1.000 | 3 | 2 | 2012 | 2017 | ||||||||
|
succinate dehydrogenase complex flavoprotein subunit A | 0.517 | 0.731 | 2.6E-10 |
|
group | 0.100 | None | 1.000 | 42 | 28 | 1995 | 2018 | ||||||||
|
succinate dehydrogenase complex subunit C | 0.517 | 0.846 | 2.0E-04 |
|
group | 0.100 | None | 1.000 | 35 | 16 | 2003 | 2018 | ||||||||
|
mutY DNA glycosylase | 0.521 | 0.769 | 1.3E-18 |
|
group | 0.100 | None | 1.000 | 123 | 83 | 2001 | 2017 | ||||||||
|
bone morphogenetic protein receptor type 1A | 0.522 | 0.731 | 0.90 |
|
group | 0.110 | None | 1.000 | 18 | 60 | 1997 | 2019 | ||||||||
|
DNA polymerase epsilon, catalytic subunit | 0.526 | 0.731 | 8.0E-27 |
|
group | 0.100 | None | 1.000 | 6 | 2 | 1996 | 2015 | ||||||||
|
MRE11 homolog, double strand break repair nuclease | 0.527 | 0.808 | 1.3E-12 |
|
group | 0.100 | None | 1.000 | 21 | 55 | 1999 | 2017 | ||||||||
|
RAD51 paralog C | 0.533 | 0.692 | 6.2E-14 |
|
group | 0.100 | None | 1.000 | 50 | 65 | 2002 | 2017 | ||||||||
|
BLM RecQ like helicase | 0.535 | 0.808 | 1.5E-15 |
|
group | 0.100 | None | 1.000 | 26 | 10 | 1995 | 2016 | ||||||||
|
folliculin | 0.537 | 0.885 | 0.79 |
|
group | 0.100 | None | 1.000 | 59 | 58 | 2000 | 2019 | ||||||||
|
MYC associated factor X | 0.553 | 0.769 | 0.83 |
|
group | 0.100 | None | 1.000 | 6 | 9 | 2003 | 2017 | ||||||||
|
myosin phosphatase Rho interacting protein | 0.556 | 0.885 | 0.98 |
|
group | 0.100 | None | 1.000 | 37 | 25 | 2000 | 2019 | ||||||||
|
RAD50 double strand break repair protein | 0.556 | 0.808 | 3.4E-27 |
|
group | 0.100 | None | 1.000 | 31 | 164 | 1999 | 2017 |