Source: ANIMAL_MODELS

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7097
Gene Symbol: TLR2
TLR2
CUI: C0024115
Disease: Lung diseases
Lung diseases 		0.250 Biomarker RGD Effect of nitric oxide on toll-like receptor 2 and 4 gene expression in rats with acute lung injury complicated by acute hemorrhage necrotizing pancreatitis. 16286274

2005
Entrez Id: 7099
Gene Symbol: TLR4
TLR4
CUI: C0024115
Disease: Lung diseases
Lung diseases 		0.240 Biomarker RGD [The role of expression of Toll-like receptor 2 and Toll-like receptor 4 in hyperoxia-induced acute lung injury in rat]. 19930876

2009
Entrez Id: 2908
Gene Symbol: NR3C1
NR3C1
CUI: C0024115
Disease: Lung diseases
Lung diseases 		0.240 Biomarker RGD Alpha glucocorticoid receptor expression in different experimental rat models of acute lung injury. 17467318

2008
Entrez Id: 7099
Gene Symbol: TLR4
TLR4
CUI: C0024115
Disease: Lung diseases
Lung diseases 		0.240 Biomarker RGD Effect of nitric oxide on toll-like receptor 2 and 4 gene expression in rats with acute lung injury complicated by acute hemorrhage necrotizing pancreatitis. 16286274

2005
Entrez Id: 2150
Gene Symbol: F2RL1
F2RL1
CUI: C0024115
Disease: Lung diseases
Lung diseases 		0.220 Biomarker RGD Gabexate mesilate inhibits the expression of HMGB1 in lipopolysaccharide-induced acute lung injury. 19766246

2011
Entrez Id: 2919
Gene Symbol: CXCL1
CXCL1
CUI: C0024115
Disease: Lung diseases
Lung diseases 		0.220 Biomarker RGD Protection against sepsis-induced lung injury by selective inhibition of protein kinase C-δ (δ-PKC). 20724665

2011
Entrez Id: 2919
Gene Symbol: CXCL1
CXCL1
CUI: C0024115
Disease: Lung diseases
Lung diseases 		0.220 Biomarker RGD Akt pathway is required for oestrogen-mediated attenuation of lung injury in a rodent model of cerulein-induced acute pancreatitis. 20709317

2011
Entrez Id: 2919
Gene Symbol: CXCL1
CXCL1
CUI: C0024115
Disease: Lung diseases
Lung diseases 		0.220 Biomarker RGD Cyclooxygenase inhibition in ventilator-induced lung injury. 21048090

2011
Entrez Id: 3162
Gene Symbol: HMOX1
HMOX1
CUI: C0024115
Disease: Lung diseases
Lung diseases 		0.220 Biomarker RGD [A study of the role of heme oxygenase-1 expression in ventilator induced lung injury and its mechanism in rats]. 20663303

2010
Entrez Id: 3586
Gene Symbol: IL10
IL10
CUI: C0024115
Disease: Lung diseases
Lung diseases 		0.220 Biomarker RGD Protective effect of carbon monoxide inhalation on lung injury after hemorrhagic shock/resuscitation in rats. 20622590

2010
Entrez Id: 3162
Gene Symbol: HMOX1
HMOX1
CUI: C0024115
Disease: Lung diseases
Lung diseases 		0.220 Biomarker RGD Heme oxygenase-1 upregulation improves lipopolysaccharide-induced acute lung injury involving suppression of macrophage migration inhibitory factor. 20638132

2010
Entrez Id: 3586
Gene Symbol: IL10
IL10
CUI: C0024115
Disease: Lung diseases
Lung diseases 		0.220 Biomarker RGD [A study of the role of heme oxygenase-1 expression in ventilator induced lung injury and its mechanism in rats]. 20663303

2010
Entrez Id: 3586
Gene Symbol: IL10
IL10
CUI: C0024115
Disease: Lung diseases
Lung diseases 		0.220 Biomarker RGD Attenuation of lipopolysaccharide-induced acute lung injury by treatment with IL-10. 19386070

2009
Entrez Id: 2919
Gene Symbol: CXCL1
CXCL1
CUI: C0024115
Disease: Lung diseases
Lung diseases 		0.220 Biomarker RGD Superimposed gastric aspiration increases the severity of inflammation and permeability injury in a rat model of lung contusion. 19515386

2009
Entrez Id: 3162
Gene Symbol: HMOX1
HMOX1
CUI: C0024115
Disease: Lung diseases
Lung diseases 		0.220 Biomarker RGD Protective effect of heme oxygenase-1 on lung injury induced by erythrocyte instillation in rats. 19024100

2008
Entrez Id: 1958
Gene Symbol: EGR1
EGR1
CUI: C0024115
Disease: Lung diseases
Lung diseases 		0.220 Biomarker RGD Early changes in lung gene expression due to high tidal volume. 12816737

2003
Entrez Id: 847
Gene Symbol: CAT
CAT
CUI: C0024115
Disease: Lung diseases
Lung diseases 		0.210 Biomarker RGD Polyphenols from Juglans regia L. (walnut) kernel modulate cigarette smoke extract induced acute inflammation, oxidative stress and lung injury in Wistar rats. 20534640

2011
Entrez Id: 2920
Gene Symbol: CXCL2
CXCL2
CUI: C0024115
Disease: Lung diseases
Lung diseases 		0.210 Biomarker RGD Protection against sepsis-induced lung injury by selective inhibition of protein kinase C-δ (δ-PKC). 20724665

2011
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
CUI: C0024115
Disease: Lung diseases
Lung diseases 		0.210 Biomarker RGD Inhibition of Rho kinase by fasudil hydrochloride attenuates lung injury induced by intestinal ischemia and reperfusion. 21056587

2011
Entrez Id: 2920
Gene Symbol: CXCL2
CXCL2
CUI: C0024115
Disease: Lung diseases
Lung diseases 		0.210 Biomarker RGD Apocynin attenuates ventilator-induced lung injury in an isolated and perfused rat lung model. 21618001

2011
Entrez Id: 2920
Gene Symbol: CXCL2
CXCL2
CUI: C0024115
Disease: Lung diseases
Lung diseases 		0.210 Biomarker RGD Akt pathway is required for oestrogen-mediated attenuation of lung injury in a rodent model of cerulein-induced acute pancreatitis. 20709317

2011
Entrez Id: 2920
Gene Symbol: CXCL2
CXCL2
CUI: C0024115
Disease: Lung diseases
Lung diseases 		0.210 Biomarker RGD Platonin mitigates acute lung injury induced by bilateral lower limb ischemia-reperfusion in rats. 20472255

2011
Entrez Id: 4843
Gene Symbol: NOS2
NOS2
CUI: C0024115
Disease: Lung diseases
Lung diseases 		0.210 Biomarker RGD A crucial role of nitric oxide in acute lung injury secondary to the acute necrotizing pancreatitis. 20144956

2010
Entrez Id: 2920
Gene Symbol: CXCL2
CXCL2
CUI: C0024115
Disease: Lung diseases
Lung diseases 		0.210 Biomarker RGD Superimposed gastric aspiration increases the severity of inflammation and permeability injury in a rat model of lung contusion. 19515386

2009
Entrez Id: 100
Gene Symbol: ADA
ADA
CUI: C0024115
Disease: Lung diseases
Lung diseases 		0.210 Biomarker RGD Zinc aspartate alleviates lung injury induced by intestinal ischemia-reperfusion in rats. 18561952

2009