Source: LHGDN

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 999
Gene Symbol: CDH1
CDH1
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms 		0.600 GeneticVariation LHGDN Identification of seven novel germline mutations in the human E-cadherin (CDH1) gene. 17221870

2007
Entrez Id: 999
Gene Symbol: CDH1
CDH1
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms 		0.600 GeneticVariation LHGDN A novel mutation in the E-cadherin gene in the first family with hereditary diffuse gastric cancer reported in Spain. 16870389

2006
Entrez Id: 999
Gene Symbol: CDH1
CDH1
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms 		0.600 GeneticVariation LHGDN CDH1/E-cadherin germline mutations in early-onset gastric cancer. 16801346

2006
Entrez Id: 999
Gene Symbol: CDH1
CDH1
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms 		0.600 Biomarker LHGDN Frequent loss of membranous E-cadherin in gastric cancers: A cross-talk with Wnt in determining the fate of beta-catenin. 16132582

2005
Entrez Id: 999
Gene Symbol: CDH1
CDH1
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms 		0.600 GeneticVariation LHGDN Characterization of a recurrent germ line mutation of the E-cadherin gene: implications for genetic testing and clinical management. 16061854

2005
Entrez Id: 999
Gene Symbol: CDH1
CDH1
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms 		0.600 GeneticVariation LHGDN CDH1 associated gastric cancer: a report of a family and review of the literature. 15780560

2005
Entrez Id: 999
Gene Symbol: CDH1
CDH1
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms 		0.600 Biomarker LHGDN Clinical significance of dysadherin expression in gastric cancer patients. 15102690

2004
Entrez Id: 999
Gene Symbol: CDH1
CDH1
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms 		0.600 GeneticVariation LHGDN Germline E-cadherin mutations in hereditary diffuse gastric cancer: assessment of 42 new families and review of genetic screening criteria. 15235021

2004
Entrez Id: 999
Gene Symbol: CDH1
CDH1
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms 		0.600 PosttranslationalModification LHGDN Prognostic analysis of E-cadherin gene promoter hypermethylation in patients with surgically resected, node-positive, diffuse gastric cancer. 15102685

2004
Entrez Id: 999
Gene Symbol: CDH1
CDH1
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms 		0.600 GeneticVariation LHGDN Association of CDH1 haplotypes with susceptibility to sporadic diffuse gastric cancer. 12444556

2002
Entrez Id: 999
Gene Symbol: CDH1
CDH1
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms 		0.600 GeneticVariation LHGDN E-cadherin gene variants in gastric cancer families whose probands are diagnosed with diffuse gastric cancer. 12216071

2002
Entrez Id: 4233
Gene Symbol: MET
MET
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms 		0.580 AlteredExpression LHGDN Gastrin and c-met protein expression were significantly higher in gastric tumor tissue than in IM (P<0.0001). 14719064

2004
Entrez Id: 1026
Gene Symbol: CDKN1A
CDKN1A
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms 		0.520 Biomarker LHGDN Upregulation of heme oxygenase-1 and p21 confers resistance to apoptosis in human gastric cancer cells. 14647439

2004
Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms 		0.500 AlteredExpression LHGDN Maspin and p53 protein expression in gastric adenocarcinoma and its clinical applications. 18091326

2008
Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms 		0.500 Biomarker LHGDN p53 is an indicator of tumor progression in early but not advanced gastric carcinomas. 18251181

2008
Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms 		0.500 Biomarker LHGDN Clinicopathologic significance of HIF-1alpha, p53, and VEGF expression and preoperative serum VEGF level in gastric cancer. 18452596

2008
Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms 		0.500 GeneticVariation LHGDN Prognostic role of p53 codon 72 polymorphism in gastric cancer patients treated with fluorouracil-based adjuvant chemotherapy. 18357466

2008
Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms 		0.500 Biomarker LHGDN Restoration of tumor suppressor miR-34 inhibits human p53-mutant gastric cancer tumorspheres. 18803879

2008
Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms 		0.500 Biomarker LHGDN Class I phosphatidylinositol 3-kinase inhibitor LY294002 activates autophagy and induces apoptosis through p53 pathway in gastric cancer cell line SGC7901. 18330473

2008
Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms 		0.500 GeneticVariation LHGDN A solitary colonic metastasis from gastric cancer detected at an early stage. 18291388

2008
Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms 		0.500 GeneticVariation LHGDN P53 codon 72 polymorphism and gastric cancer: a meta-analysis of the literature. 17546594

2007
Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms 		0.500 GeneticVariation LHGDN Interaction of P53 Arg72Pro and MDM2 T309G polymorphisms and their associations with risk of gastric cardia cancer. 17638920

2007
Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms 		0.500 AlteredExpression LHGDN The data on p53 abnormalities, when considered separately, could be of relative value for predicting the behavior of gastric tumors. 17436385

2007
Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms 		0.500 AlteredExpression LHGDN Identification and characterization of a novel germ line p53 mutation in familial gastric cancer in the Japanese population. 17690113

2007
Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms 		0.500 GeneticVariation LHGDN A p53 genetic polymorphism of gastric cancer: difference between early gastric cancer and advanced gastric cancer. 17072987

2006